SUMMARY. Reconstruction of full-thickness defects with the use of artificial dermis has been well established in the recent literature. The capacity of artificial dermis to expand over a period of years, months, or even days is described. Three such cases are reported. Two females (aged 21 and 30 yr) post-burn contractures of the chest wall right breast hypoplasia and abdominal wall post-burn contractures. The third patient, a 14-yr-old male with a giant congenital naevus on the forearm, is also described. After excision of the contractures and the congenital naevus, the patients underwent staged reconstruction with the use of artificial dermal template and splitthickness skin autografts at monthly intervals. The 21-yr-old female also had a tissue expander placed submuscularly which six months later was replaced by a permanent silicone implant. Gradual expansion of artificial dermis within three weeks resulted in reconstruction of a breast of natural shape, size, and volume. In the second patient the artificial dermis was expanded over a period of months, until full-term pregnancy, while the third patient took years to achieve expansion naturally as he grew up. In conclusion, artificial dermis can be expanded over various periods of time (days to years), providing a reliable and safe alternative reconstructive method, particularly in areas where expansion is an absolute necessity for a good functional and aesthetic result