ABSTRACT The disposition of ketoprofen enantiomers has been studied in 1 2 rabbits with normal renal function (control) and in 6 of these rabbits with renal dysfunction. In control animals a mean (S.E.M.) of 0.09 (0.01) of R-ketoprofen was inverted to its S-enantiomer. The mean distribution volumes for A-and S-ketoprofen were 114 (7.4) and 29
