Enantioselective Disposition of 2-Aryipropionic Acid Nonsteroidal Anti-Inflammatory Drugs. Ill. Fenoprofen Disposition'

Abstract

ABSTRACT The formation of the acylglucuronides of clofibric acid (Odum and Orton, 1983) and diflunisal (Faed et al., 1984) has also been reported to be induced by phenobarbital. Based on the above observations we have examined the effect ofphenobarbital on fenoprofen disposition and its enantiomeric consequences. ABBREVIATIONS: Cl5