Abstract As a preliminary research of development of a comprehensive management tool for organizational sustainability, this paper discusses the difficulty of achieving organizational sustainability in today's complex business environment. It explains why Analytic Network Process (ANP), a general form of Analytic Hierarchy Process (AHP), is an appropriate approach to the project portfolio management for success in organizational sustainability. It proposes a generic ANP model via the Triple Bottom Line (TBL) framework for the evaluation and prioritization of projects based on their potential contribution to an organization's sustainability initiative. The paper then demonstrates the model through an illustrative problem