A gradient of plasma polymerization of pyrrole was generated to model a chemoattractant surface; it was obtained by changing the polymerization time to manipulate the thickness and the deposited layer. The polymerization was generated with a power of 30W on a cylindrical vacuum reactor, the coverslip was polymerized covered by a cavity with a surface exposed of 0.7 cm every 35 min., the cells seeded were liver stellate cells (Ito); it was evaluated against a coverslip with continuous plasma polymerization of pyrrole (Ppy). The results show similar protein secretions, but cells proliferation was selective in the surface gradient regions