INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES Antibacterial activity of freshwater Mussel Parreysia corrugata (Muller 1774) from Lower Anaicut Reservoir, India

Abstract

Abstract In the present study aqueous, ethanol and methanol extracts of freshwater mussel Parreysia corrugata were screened for antibacterial activity. The extracts were obtained from the whole body tissue of the animals and tested against 5 pathogenic bacteria viz., Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella typhi, Enterococcus faecalis and Staphylococcus aureus. Ethanol extract of P.corrugata showed maximum antibacterial activity 11 mm against P.aeruginosa and the minimum activity 9 mm against K. pneumoniae. Methanol extract of P.corrugata showed Maximum inhibition 13mm against P.aeruginosa and the minimum inhibition zone of 8mm against K. pneumoniae. Aqueous extract of P.corrugata showed the maximum inhibition zone was 10mm against S.aureus and the minimum inhibition zone was 7 mm against S.typhi. Aqueous, Ethanol and Methanol extracts showed antibacterial activity against five human pathogen bacteria tested. Compare to water extracts Ethanol and Methanol extracts showed more activity against all pathogens. FTIR analysis revealed the presence of bioactive compounds signals at different ranges