Comparative study of microwave assisted and conventional synthesis of novel 2-quinoxalinone3- hydrazone derivatives and its spectroscopic properties

Abstract

A series of novel quinoxalin-2(1H)-one-3-hydrazone derivatives, 2a -8d were synthesized via condensation of 3-hydrazinoquinoxalin-2(1H)-one, 1, with the corresponding ketones under microwave irradiation. The microwave assisted reaction was remarkably successful and gave hydrazones in higher yield at less reaction time compared to conventional heating method. The chemical structures of the compounds prepared were confirmed by analytical and spectral data