Abstract: Knowledge management activity is a relevant construct for the analysis of the organization and functional behavior in primary care practices. The increased interest in knowledge management framework can be associated to many elements including the advances in information and communication technologies; data and information overload; and, the need for managing and utilizing intellectual organization resources. Various researches investigated and developed knowledge management framework to assist healthcare clinicians in managing the practices and quality care to patients. A drug rehabilitation centre confronts information overloading of drug treatment related information which lead to ineffective and inefficient of drug rehabilitation treatment and progress monitoring. Therefore, this research aims to investigate the drug rehabilitation centre on improving the dissemination of knowledge. It is an investigation research that ventures into emerging and potentially transformative research ideas which focuses on various levels of surveys, observation and interviews. This research will involve several steps including literature review and information gathering identification of initial framework properties. These steps will be performed in an incremental manner. In terms of scope it is limited to focus on the impact of knowledge management practices on measuring the effectiveness and dissemination of knowledge in drug rehabilitation centre