ABSTRACT Medicinal plants can provide biologically active molecules and lead structures for the development of modified derivatives with enhanced activity and or reduced toxicity. Ensuring the safety, efficacy and quality of traditional medicine is a priority in as much as it must be respected, preserved and promoted as a branch of medicine. In plants, the medicinal value of the secondary metabolites is due to the presence of chemical substances that produce a definite physiological action on the human body. Research into the isolated plant constituents is of great importance for the development of bioactive substances from ethnic medicine. With the emergence of latest technologies and enhanced knowledge about the isolated plant constituents, characterization and analytical tools, lot of compounds are efficiently isolated from potential plants and have been of great contribution to the drug discovery from ethnic plants. The present investigation is aimed at investigating the phytochemical evaluation, quantification and antioxidant studies of a medicinal plant Glycosmis mauritiana. The phytochemical quantification was done for phenolics, tannins and flavanoids. The antioxidant screening was done by FRAP assay and DPPH free radical scavenging assay, using five different solvent extracts. Significant antioxidant activity of ethanolic extracts was recorded in Glycosmis mauritiana which can be used as a potent source of natural antioxidant