森 佳洋

水口 峰之

篠田 裕之

水口, 峰之

森, 佳洋

篠田, 裕之

University of Toyama Repository

????? Physical Pharmacy ???????? Structural Biology  ???   ?? ??  Mineyuki Mizuguchi ? ?   ?  ??  Yoshihiro Mori ? ?   ?? ??  Hiroyuki Shinoda  ? ? ? 1) ??????????SBO 23  ???????????????????????????????????????????. ????????????? 2 ????? III. ??????????????????????????, ??????, ??, 127-132, 2006.  ? ? ? 1) Sato, T., Ando, Y., Susuki, S., Mikami, F., Ikemizu, S., Nakamura, M., Suhr, O., Anraku, M., Kai, T., Suico, M. A., Shuto, T., Mizuguchi, M., Yamagata, Y. and Kai, H. Chromium (III) ion and thyroxine cooperate to stabilize the transthyretin tetramer and suppress in vitro amyloid fibril formation. FEBS Lett. 580: 491-496, 2006. 2) Marchesini, G. R., Meulenberg, E., Haasnoot, W., Mizuguchi, M. and Irth, H. Biosensor recognition of thyroid-disrupting chemicals using transport proteins. Anal Chem, 78: 1107-1114, 2006. 3) Shinoda, H., Mori, Y. and Mizuguchi, M. Reinvestigation into the ring-opening process of monochloroethylene oxide by quantum chemical calculations. Int J Quantum Chem, 106: 952-959, 2006. 4) Tada, M., Shinohara, Y., Kato, I., Hiraga, K., Aizawa, T., Demura, M., Mori, Y., Shinoda H., Mizuguchi, M. and Kawano, K. Preparation and observation of fresh-frozen sections of the green fluorescent protein transgenic mouse head. Acta Histochem Cytochem, 39: 31-34, 2006. 5) Watanabe, S., Tada, M., Aizawa, T., Yoshida, M., Sugaya, T., Taguchi, M., Kouno, T., Nakamura, T., Mizuguchi, M., Demura, M., Hayakawa, Y. and Kawano, K. N-Terminal mutational analysis of the interaction between growth-blocking peptide (GBP) and receptor of insect immune cells. Protein Pept. Lett, 13: 815-822, 2006. 6) Mori Y., Shinoda H., Nakano T., Takasu R., and Kitagawa T.: Laser-induced formation of pyrenyloxy radical from 1-hydroxypyrene and further oxidation: Micellar effects. J. Photochem. Photobiol. A: Chemistry, 182: 168-173, 2006.  ? ???? 1) ????? ????????? ????? ?????? ?????????? ?????Pyrrolidone carboxyl peptidase? C????????????????????????????? 6??????????2006?4???? 2) ????????????????????????????????????????????????? roadblock? DL2A??????? 6??????????2006?4???? 3) ????????????????????????????????????????????????????????????? 6??????????2006?4???? 4) ????????????????????????????????????????????????????????????????? tachystatin B????????? 6??????????2006?4???? 5) ?????????????????????????????? CIDNP??????????????? 6??????????2006?4???? 6) ??????????????????????????????????????????? GBP? N-?????????????????????????????????? 6??????????2006?4???? 7) Iimura, S., Umezaki, T., Takeuchi, M., Mizuguchi, M., Ogasahara, K., Yagi, H., Akutsu, H., Noda, Y., Segawa, S. and Yutani, K. Role of the C-terminal α-helix in folding and stability of pyrrolidone carboxyl peptidase from a hyperthermophile. 20th Annual Symposium of the Protein Society & 20th Anniversary Celebration. August 5-9, 2006, San Diego, CA. USA. 8) Kouno, T., Mizuguchi, M., Mori, Y., Tanida, I., Ueno, T., Kominami, E. and Kawano, K. Observation of protein binding to membrane with photo-CIDNP technique. XXIIND International Conference on Magnetic Resonance in Biological Systems. August 20-25, 2006, Göttingen, Germany.   9) Saito, S. Aizawa, T. Kamiya, M. Kumaki, Y. Mizuguchi, M. Takiya, S. *Demura, M. and Kawano, K. Solution structure of DNA-binding units of FMBP-1 and the role of the four units in DNA-binding. XXIIND International Conference on Magnetic Resonance in Biological Systems. August 20-25, 2006, Göttingen, Germany.   10) Soejima, M., Mizuguchi, M., Igarashi, Y., Nabeshima, Y., Mori, Y., Shinoda, H. and Kawano, K. Transthyretin mutations and neurotoxicity. Fifth East Asian Biophysics Symposium & Forty-Fourth Annual Meeting of the Biophysical Society of Japan, November 12-16, 2006, Okinawa Convention Center. 11) Nagai, Y., Mizuguchi, M., Sitoh, D., Takeuchi, M., Nabeshima, Y., Mori, Y., Shinoda, H. and Kawano, K. Proline-scanning mutagenesis of transthyretin and its effect on the intermediate structure. Fifth East Asian Biophysics Symposium & Forty-Fourth Annual Meeting of the Biophysical Society of Japan, November 12-16, 2006, Okinawa Convention Center. 12) Takeuchi, M., Mizuguchi, M., Dobashi, M., Mori, Y., Shinoda, H. and Kawano, K. Amyloid fibril formation of a peptide fragment of transthyretin. Fifth East Asian Biophysics Symposium & Forty-Fourth Annual Meeting of the Biophysical Society of Japan, November 12-16, 2006, Okinawa Convention Center. 13) Bak, S., Kamiya, M., Umetsu, Y., Aizawa, T., Kouno, T., Mizuguchi, M., Kumaki, Y., Demura, M. and Kawano, K. Fast backbone amide assignment of 15N-HSQC spectrum. Fifth East Asian Biophysics Symposium & Forty-Fourth Annual Meeting of the Biophysical Society of Japan, November 12-16, 2006, Okinawa Convention Center. 14) Sugita, K., Ohkubo, T., Kamiya, M., Kamijima, T., Shimamoto, S., Tatami, F., Aizawa, T., Mizuguchi, M.,. Kawabata, S., Demura, M. and Kawano, K. Structure of tachyplesin I bound to dodecylphosphocholine micelles. Fifth East Asian Biophysics Symposium & Forty-Fourth Annual Meeting of the Biophysical Society of Japan, November 12-16, 2006, Okinawa Convention Center. Fifth East Asian Biophysics Symposium & Forty-Fourth Annual Meeting of the Biophysical Society of Japan, November 12-16, 2006, Okinawa Convention Center. 15) Umetsu, Y., Aizawa, T., Muto, K., Yamamoto, H., Kamiya, M., Kumaki, Y., Mizuguchi, M., Demura, M., Hayakawa, Y. and Kawano, K. Structure-activity relationships and C-terminal elongation effects of Growth-blocking peptide. Fifth East Asian Biophysics Symposium & Forty-Fourth Annual Meeting of the Biophysical Society of Japan, November 12-16, 2006, Okinawa Convention Center. 16) Iimura, S., Umezaki, T., Takeuchi, M., Mizuguchi, M., Ogasahara, K., Yagi, H., Akutsu, H., Noda, Y., Segawa S. and Yutani K. H/D exchange characterization of the C-terminal α-helix in the denatured state of pyrrolidone carboxyl peptidase from a hyperthermophile. Fifth East Asian Biophysics Symposium & Forty-Fourth Annual Meeting of the Biophysical Society of Japan, November 12-16, 2006, Okinawa Convention Center.  ? ??? 1) ????????????????????????????????????????????????????????????2005?3?????? ??????? 2) Takeuchi M., Mizuguchi M., Kouno T., Ohki S., Yutani K., Kawano K. :NMR investigation of the refolding intermediate of pyrrolidone carboxyl peptidase from a hyperthermophile. ??????????????????????????? 3???????????2006?1????????? ?????????????????????? 3) ??????? dynein light chain??????????? NMR???????. ?????????????????????????????????? ???????????? in???, 2006?2???????????????? 4) ??????????????????????????????????????????????????????????2006?3???????????????????? 5) ????????????????????????????????????? ?????????????????????????????????????????????????????????????????2006?12???????????????????????? 6) ?????????????????????????????????PQBP-1?? C??????? hDim1??????????????????????????????????????????????2006?12???????????????????????? 7) ?????????????????????????????????Gelsolin domain-2? amyloid beta-peptide???????????????????????????????????????????2006?12???????????????????????? 8) ?????????????????????????????????Amyloid beta-peptide???????????????????????????????????????????????2006?12???????????????????????? 9) Takeuchi, M., Mizuguchi, M., Nabeshima, Y., Yutani, K., Kawano, K. The intermediate structure of pyrrolidone carboxyl peptidase studied by site-directed spin labeling and NMR. ??????????????????????????? 4???????????2006?12?????????????? 

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Physical Pharmacy, Structural Biology

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