942,254 research outputs found
Collegiality: An Atmosphere For Expanding Intellectual Stimulation
Libraries are the arena where intellectual interaction takes place through the universal conversation of scholarship. Librarians share a common commitment to learning and service. In addition Christian librarians share a calling to knowledge and service that comes from the Holy Scriptures. Aspects of integrating our Christian faith, through the professional environment we create in our workplace, are considered. Collegiality as the means to achieve a productive library ambience for scholarship is suggested. When a Library has an atmosphere conducive to promoting learning it is a place of intellectual stimulation where the culture is collegial and the values of Christianity are practiced
Distributed Access View Integrated Database (DAVID) system
The Distributed Access View Integrated Database (DAVID) System, which was adopted by the Astrophysics Division for their Astrophysics Data System, is a solution to the system heterogeneity problem. The heterogeneous components of the Astrophysics problem is outlined. The Library and Library Consortium levels of the DAVID approach are described. The 'books' and 'kits' level is discussed. The Universal Object Typer Management System level is described. The relation of the DAVID project with the Small Business Innovative Research (SBIR) program is explained
National Library of Malaysia Annual Report 2001
This Annual Report reflects the PNM activities during 2001, to support their vision,"The National Library of Malaysia aspires to be a world class library in the provision of excellent information services towards the realization of Malaysia's vision of becoming an industrialised and developed nation by the year 2020." and mission,"To ensure that all Malaysians have equal access to library services and facilities as well the ability to utilise Malaysian and universal intellectual heritage knowledge through a national infrastructure of integrated electronic libraries.
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Fluorescent amplification for next generation sequencing (FA-NGS) library preparation.
BACKGROUND:Next generation sequencing (NGS) has become a universal practice in modern molecular biology. As the throughput of sequencing experiments increases, the preparation of conventional multiplexed libraries becomes more labor intensive. Conventional library preparation typically requires quality control (QC) testing for individual libraries such as amplification success evaluation and quantification, none of which occur until the end of the library preparation process. RESULTS:In this study, we address the need for a more streamlined high-throughput NGS workflow by tethering real-time quantitative PCR (qPCR) to conventional workflows to save time and implement single tube and single reagent QC. We modified two distinct library preparation workflows by replacing PCR and quantification with qPCR using SYBR Green I. qPCR enabled individual library quantification for pooling in a single tube without the need for additional reagents. Additionally, a melting curve analysis was implemented as an intermediate QC test to confirm successful amplification. Sequencing analysis showed comparable percent reads for each indexed library, demonstrating that pooling calculations based on qPCR allow for an even representation of sequencing reads. To aid the modified workflow, a software toolkit was developed and used to generate pooling instructions and analyze qPCR and melting curve data. CONCLUSIONS:We successfully applied fluorescent amplification for next generation sequencing (FA-NGS) library preparation to both plasmids and bacterial genomes. As a result of using qPCR for quantification and proceeding directly to library pooling, the modified library preparation workflow has fewer overall steps. Therefore, we speculate that the FA-NGS workflow has less risk of user error. The melting curve analysis provides the necessary QC test to identify and troubleshoot library failures prior to sequencing. While this study demonstrates the value of FA-NGS for plasmid or gDNA libraries, we speculate that its versatility could lead to successful application across other library types
One size fits all: equilibrating chemically different polymer liquids through universal long-wavelength description
Mesoscale behavior of polymers is frequently described by universal laws.
This physical property motivates us to propose a new modeling concept, grouping
polymers into classes with a common long-wavelength representation. In the same
class samples of different materials can be generated from this representation,
encoded in a single library system. We focus on homopolymer melts, grouped
according to the invariant degree of polymerization. They are described with a
bead-spring model, varying chain stiffness and density to mimic chemical
diversity. In a renormalization group-like fashion library samples provide a
universal blob-based description, hierarchically backmapped to create
configurations of other class-members. Thus large systems with
experimentally-relevant invariant degree of polymerizations (so far accessible
only on very coarse-grained level) can be microscopically described.
Equilibration is verified comparing conformations and melt structure with
smaller scale conventional simulations
Tight Bounds on the Synthesis of 3-bit Reversible Circuits: NFT Library
The reversible circuit synthesis problem can be reduced to permutation group.
This allows Schreier-Sims Algorithm for the strong generating set-finding
problem to be used to find tight bounds on the synthesis of 3-bit reversible
circuits using the NFT library. The tight bounds include the maximum and
minimum length of 3-bit reversible circuits, the maximum and minimum cost of
3-bit reversible circuits. The analysis shows better results than that found in
the literature for the lower bound of the cost. The analysis also shows that
there are 1960 universal reversible sub-libraries from the main NFT library.Comment: 18 pages. arXiv admin note: text overlap with arXiv:1101.438
Australian public library alliance achievements 2010-2015
Overview: The ALIA Australian Public Library Alliance (APLA) is the peak body for public libraries in Australia. Our committee comprises the chair of every state-based public library association, a senior representative from the ACT, Northern Territory and Tasmanian library services, and expert members. We represent 94% of all the 1500 public libraries across Australia through membership subscription.
APLA (or, as it was previously known, the ALIA Public Libraries Advisory Committee) was formed following a highly successful ALIA Public Libraries Summit in July 2009. At the summit, libraries leaders called for, ‘Australia’s public libraries, united behind common goals and ambitions, sharing best practice, contributing to strong communities, valued by people and government, continuing to provide universal free access to information, knowledge and ideas, and confirming the importance of their role for future generations.’
A national alliance, supported by every state and territory, and Public Libraries Australia, was the primary outcome of the summit and was ratified by the signing of a Memorandum of Collaboration in July 2010
BigraphER: rewriting and analysis engine for bigraphs
BigraphER is a suite of open-source tools providing an effi-
cient implementation of rewriting, simulation, and visualisation for bigraphs,
a universal formalism for modelling interacting systems that
evolve in time and space and first introduced by Milner. BigraphER consists
of an OCaml library that provides programming interfaces for the
manipulation of bigraphs, their constituents and reaction rules, and a
command-line tool capable of simulating Bigraphical Reactive Systems
(BRSs) and computing their transition systems. Other features are native
support for both bigraphs and bigraphs with sharing, stochastic reaction
rules, rule priorities, instantiation maps, parameterised controls, predicate
checking, graphical output and integration with the probabilistic
model checker PRISM
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