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Build your Responsive Open Learning Environment
The European research project ROLE (Responsive Open Learning Environments) is aiming at empowering learners for self-regulated learning within a personalised learning environment. Towards this goal, ROLE has developed a number of learning technologies, addressing a variety of learning requirements. The purpose of this roundtable is to discuss the applications of these technologies in different learning contexts, as well as the challenges associated with enabling and supporting self-regulated learning
Role of mycobacteria-induced monocyte/macrophage apoptosis in the pathogenesis of human tuberculosis
The role of biomechanics in the assessment of carotid atherosclerosis severity: a numerical approach
Numerical fluid biomechanics has been proved to be an efficient tool for understanding vascular diseases including atherosclerosis. There are many evidences that atherosclerosis plaque formation and rupture are associated with blood flow behavior. In fact, zones of low wall shear stress are vivid areas of proliferation of atherosclerosis, and in particular, in the carotid artery. In this paper a model
is presented for investigating how the presence of the plaque influences the distribution of the wall shear stress. In complement to a first approach with rigid walls, an FSI model is developed as well to simulate the coupling between the blood flow and the carotid artery deformation. The results show that the presence of the plaque causes an attenuation of the WSS in the after-plaque region as well as the emergence of recirculation areas
The cost of soil replacement : a Maltese case study
Soil erosion only enters national accounting systems when soil loss is reflected in lost agricultural productivity, or becomes manifest with costs sustained by damage through flooding, siltation of dams, landslides, and other associated phenomena. On islands that are prone to desertification, however, soil loss needs to be better accounted since the costs of soil replacement and rehabilitation are often prohibitively expensive. Circumscribed agricultural space provides the necessary incentive for investment in soil conservation measures and, in certain cases, a long history of such measures results in a wealth of soil retention structures. Soil conservation has been practised in the densely populated Maltese islands for several hundred years. Slope terracing and armouring of the terrace face with retaining dry stonewalls represents a rich resource which has not yet been quantified. Yet the cost of maintaining such soil conservation structures is becoming increasingly prohibitive despite the downstream costs of their eventual failure. Legislation has been enacted aimed at preserving rubble walls since these are now also regarded as a unique landscape feature but well-targeted economic incentives and support infrastructures are crucial in this regard. In fact, the Maltese Government has, over the past few years, promoted rubble wall repairs by creating groups of skilled workers trained in the craft of rubble wall building. Malta's joining the European Union in May 2004 also means that EU funds would be utilised in this regard but this needs careful management. Despite such state initiatives, alternative non-state subsidies need to be identified and this demands the identification of net beneficiaries of soil conservation. The most easily identifiable stakeholders are farmers but the tourist sector and water management authorities should also be enlisted within soil conservation management. Other stakeholders include those sectors that are adversely affected by soil erosion. In this case, insurance companies and road maintenance agencies should also be involved in soil management initiatives.peer-reviewe
Investigation of the Role of Plasticizers in Film-forming Coats for Protecting Cooled Meat
As a result of theoretical studies on problems of protection and prolongation of storage terms of meat, it was revealed, that one of promising directions is to use protecting coats, based on natural biopolymers.The topicality of this study is in studying film-forming coats, based on natural polysaccharides, because they have high mechanical indices, absence of a smell, taste and are subjected to biological destruction. For regulating mechanical properties, the composition of film-creating coats is added with plasticizers of different origins.The aim of this work is in describing characteristics of food films, based on carrageenan, sodium alginate and plasticizers of different origins.There were mechanical, rheological properties of protecting coats. The comparative characteristic of these properties, depending on an added plasticizer, was realized. The type and mechanisms of interaction of components of the film-forming coat and plasticizers were completely described. The viscosity of the film-forming coat with a plasticizer has less values comparing with other solutions. Adding plasticizers resulted in increasing the film elasticity, but at the same time some increase of the firmness was observed.Film-forming coats with adding a plasticizer had a higher limit of fluidity, so they were firmer than complex film-forming coats without a plasticizer. From the other side, deformation values of film-forming coats without adding a plasticizer were higher than ones of complex film-forming coats with adding a plasticizer, because they were firmer.The study of physical properties of developed film-forming coats, based on hydrocolloids, demonstrated that coats with a plasticizer have more gas permeability.According to the results, obtained at experiments it was established, that the film-forming coat, based on sodium alginate, carrageenan and glycerin, has best mechanical, physical and rheological indices
The Role of Intensive Insulin Therapy on Superoxide Dismutase (Sod), Tumor Necrosis Factor-? (Tnf-?), and Interleukin-6 (Il-6) on Hyperglycemia in Critically Ill Patients
Hyperglycemia and insulin resistance are common in critically ill patientsin the ICU, although they have not previously had diabetes. It has been reportedthat pronounced hyperglycemia may lead to complications in such patients, andcause the reactive oxygen species (ROS) production, although controlled trial dataare still lacking. The current debatable issue, focusing on whether the intensiveinsulin therapy, aimed at normalizing blood glucose, may improvepatients'prognosis. Then, the debate is mainly about the time to start the therapy,and target of blood glucose level. Therefore, this research is mainly designed andaimed at knowing the difference between intensive insulin therapy andconventional insulin therapy on the increase of superoxide dismutase (SOD),decrease of cytokine production (TNF-? and IL-6), increase of albumin level, andevent of SIRSThis study was carried out in a randomly pre and post-test control groupdesign, involving 40 adult patients being nursed through the ICU Sanglah hospitalDenpasar. They were randomly assigned to receive intensive insulin therapy, inwhich blood glucose was decreased and maintained at the level between 80-110mg/dl, or conventional insulin therapy in which the insulin was infused only if theblood glucose level exceeded 215 mg/dl, decreased and maintained then at thelevel between 180-200 mg/dl.The result of the study showed that there was (1) significant increase ofSOD mean level (370. 70 vs 98.50 U/gHb, p=0.001); (2) no significant decreaseof TNF-? mean level; (3) significant decrease of IL-6 mean level (10.26 vs 2.25;p=0.023); (4) significant increase of albumin mean level ( 0.62 vs 0.22); (5)significant decrease of SIRS (10 % vs 40 %, p=0.000) on intensive insulin therapygroup compared to conventional insulin therapy group. It can be concluded thatintensive insulin therapy could maintain blood glucose level between 80 – 110mg/dl, increase SOD level, decrease IL-6 level, increase albumin level, anddecrease SIRS on hyperglycemia in critically ill ICU patients
The Changing Role of Family Income and Ability in Determining Educational Achievement
This paper uses data from the 1979 and 1997 National Longitudinal Survey of Youth cohorts (NLSY79 and NLSY97) to estimate changes in the effects of ability and family income on educational attainment for youth in their late teens during the early 1980s and early 2000s. Cognitive ability plays an important role in determining educational outcomes for both NLSY cohorts, while family income plays little role in determining high school completion in either cohort. Most interestingly, we document a dramatic increase in the effects of family income on college attendance (particularly among the least able) from the NLSY79 to the NLSY97. Family income has also become a much more important determinant of college `quality' and hours/weeks worked during the academic year (the latter among the most able) in the NLSY97. Family income has little effect on college delay in either sample. To interpret our empirical findings on college attendance, we develop an educational choice model that incorporates both borrowing constraints and a `consumption' value of schooling - two of the most commonly invoked explanations for a positive family income-schooling relationship. Without borrowing constraints, the model cannot explain the rising effects of family income on college attendance in response to the sharply rising costs and returns to college experienced from the early 1980s to early 2000s: the incentives created by a `consumption' value of schooling imply that income should have become less important over time (or even negatively related to attendance). Instead, the data are more broadly consistent with the hypothesis that more youth are borrowing constrained today than were in the early 1980s.
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