A lifeline for Europe's young radical innovators

In this Policy Brief, Reinhilde Veugelers shows that Young Innovative Companies (YICs) in Europe achieve significantly higher innovative sales than other innovation-active firms, representing 36% of sales having market novelties. She also confirms that YICs are more affected by credit constraints than other innovation-active firms. If Europe is to exit the current crisis intact and fulfill its full growth potential in the medium term, the author therefore believes Europe must develop policies and incentives which are tailored to the needs of European young radical innovators.

Radical-Enhanced Chinese Character Embedding

We present a method to leverage radical for learning Chinese character embedding. Radical is a semantic and phonetic component of Chinese character. It plays an important role as characters with the same radical usually have similar semantic meaning and grammatical usage. However, existing Chinese processing algorithms typically regard word or character as the basic unit but ignore the crucial radical information. In this paper, we fill this gap by leveraging radical for learning continuous representation of Chinese character. We develop a dedicated neural architecture to effectively learn character embedding and apply it on Chinese character similarity judgement and Chinese word segmentation. Experiment results show that our radical-enhanced method outperforms existing embedding learning algorithms on both tasks.Comment: 8 pages, 4 figure

A Comparative Study of Extreme Religious Nationalist Terrorist Groups in the United States

The aim of this paper is to conduct a comparative study of Radical Right Wing terrorism and Radical Islamic terrorism both of which are categorized under the Religious Nationalism/Extremism typology of terrorism. In order to compare and contrast the two fairly, I broke down the ideology, motives, methods, and the demographic profile of members of both Radical Right Wing and Radical Islamic terrorism then provided examples of different groups that fall within those categories in order to effectively illustrate the striking similarities of the two categories that have been addressed and condemned differently by the United States. Then I had analyzed how and why the United States has approached groups that fall under Radical Right Wing terrorism vastly different than groups under Radical Islamic terrorism even though both fall under the same Religious Nationalism/Extremism category of terrorism. This comparative study is also being conducted to examine why the United States did not have the same reaction to Radical Right Wing terrorist groups before the September 11th attacks as it did to the Radical Islamic groups since Radical Right Wing groups had committed the most violent acts in the United States prior to September 11th 2001. Lastly, I will also briefly discuss the present day social implications associated with the difference of treatment between the two terrorist groups.https://scholarscompass.vcu.edu/uresposters/1289/thumbnail.jp

Radical versus Non-Radical Inventions

This paper looks at the special characteristics of radical inventions. It tries to identify those variables that differentiate radical inventions from non-radical inventions. Since radical inventions are very important for the economy as a whole and for the individual firm performances, understanding what makes radical inventions differ from non-radical inventions is very important. For our research we made use of the EPO (European Patent Office) database on patents. We used the number of forward patent citations per patent to identify radical from non-radical inventions. For our analysis we used the backward patent citations per patent. In order to test if the two groups we are considering are truly different and to see on what factors they differ we made use of discriminant function analysis. Some of our main conclusions are that radical inventions are to a higher degree based on existing knowledge than non-radical inventions. Also the combination of emergent and mature knowledge is more important for radical inventions. A further result that follows from our analysis is that radical inventions are induced by the recombination over more knowledge domains as compared to non-radical inventions. Our research hints also on the importance of alliances and an open innovation system for the development of radical inventions.radical inventions, patents, organizational learning, alliances

Spectroscopic and theoretical approaches for studying radical reactions in class I ribonucleotide reductase

Ribonucleotide reductases (RNRs) catalyze the production of deoxyribonucleotides, which are essential for DNA synthesis and repair in all organisms. The three currently known classes of RNRs are postulated to utilize a similar mechanism for ribonucleotide reduction via a transient thiyl radical, but they differ in the way this radical is generated. Class I RNR, found in all eukaryotic organisms and in some eubacteria and viruses, employs a diferric iron center and a stable tyrosyl radical in a second protein subunit, R2, to drive thiyl radical generation near the substrate binding site in subunit R1. From extensive experimental and theoretical research during the last decades, a general mechanistic model for class I RNR has emerged, showing three major mechanistic steps: generation of the tyrosyl radical by the diiron center in subunit R2, radical transfer to generate the proposed thiyl radical near the substrate bound in subunit R1, and finally catalytic reduction of the bound ribonucleotide. Amino acid- or substrate-derived radicals are involved in all three major reactions. This article summarizes the present mechanistic picture of class I RNR and highlights experimental and theoretical approaches that have contributed to our current understanding of this important class of radical enzymes

A supramolecular radical cation: folding-enhanced electrostatic effect for promoting radical-mediated oxidation.

We report a supramolecular strategy to promote radical-mediated Fenton oxidation by the rational design of a folded host-guest complex based on cucurbit[8]uril (CB[8]). In the supramolecular complex between CB[8] and a derivative of 1,4-diketopyrrolo[3,4-c]pyrrole (DPP), the carbonyl groups of CB[8] and the DPP moiety are brought together through the formation of a folded conformation. In this way, the electrostatic effect of the carbonyl groups of CB[8] is fully applied to highly improve the reactivity of the DPP radical cation, which is the key intermediate of Fenton oxidation. As a result, the Fenton oxidation is extraordinarily accelerated by over 100 times. It is anticipated that this strategy could be applied to other radical reactions and enrich the field of supramolecular radical chemistry in radical polymerization, photocatalysis, and organic radical battery and holds potential in supramolecular catalysis and biocatalysis