protocol

Background Clinical trials on caries lesion management use an abundance of outcomes, hampering comparison or combination of different study results and their efficient translation into clinical practice. Core outcome sets are an agreed standardized collection of outcomes which should be measured and reported in all trials for a specific clinical area. We aim to develop a core outcome set for trials investigating management of caries lesions in primary or permanent teeth conducted in primary or secondary care encompassing all stages of disease. Methods To identify existing outcomes, trials on prevention and trials on management of caries lesions will be screened systematically in four databases. Screening, extraction and deduplication will be performed by two researchers until consensus is reached. The definition of the core outcome set will by based on an e-Delhi consensus process involving key stakeholders namely patients, dentists, clinical researchers, health economists, statisticians, policy-makers and industry representatives. For the first stage of the Delphi process, a patient panel and a separate panel consisting of researchers, clinicians, teachers, industry affiliated researchers, policy- makers, and other interested parties will be held. An inclusive approach will be taken to involve panelists from a wide variety of socio-economic and geographic backgrounds. Results from the first round will be summarized and fed back to individuals for the second round, where panels will be combined and allowed to modify their scoring in light of the full panel’s opinion. Necessity for a third round will be dependent on the outcome of the first two. Agreement will be measured via defined consensus rules; up to a maximum of seven outcomes. If resources allow, we will investigate features that influence decision making for different groups. Discussion By using an explicit, transparent and inclusive multi-step consensus process, the planned core outcome set should be justifiable, relevant and comprehensive. The dissemination and application of this core outcome set should improve clinical trials on managing caries lesions and allow comparison, synthesis and implementation of scientific data

pH Protocol

The purpose of this resource is to measure the pH of water. Students use either a pH meter or pH paper to measure the pH. If using the pH meter, the meter needs to be calibrated with buffer solutions that have pH values of 4, 7, and 10. Educational levels: Primary elementary, Intermediate elementary, Middle school, High school

Unconditionally secure quantum key-distribution with relatively strong signal pulse

We propose an unconditionally secure quantum key distribution (QKD) protocol, which uses a relatively strong signal pulse. While our protocol shares similar security bases as the Bennett 1992 protocol with a strong reference pulse (B92), our scheme uses a smaller number of detectors and it is robust against Rayleigh scattering in an optical fibre. We derive a lower bound of secret key generation rate of our protocol and show that our protocol can cover relatively long distances, assuming precise phase modulations and stable interferometers.Comment: 4 page

TSEP: Threshold-sensitive Stable Election Protocol for WSNs

Wireless Sensor Networks (WSNs) are expected to find wide applicability and increasing deployment in near future. In this paper, we propose a new protocol, Threshold Sensitive Stable Election Protocol (TSEP), which is reactive protocol using three levels of heterogeneity. Reactive networks, as opposed to proactive networks, respond immediately to changes in relevant parameters of interest. We evaluate performance of our protocol for a simple temperature sensing application and compare results of protocol with some other protocols LEACH, DEEC, SEP, ESEP and TEEN. And from simulation results it is observed that protocol outperforms concerning life time of sensing nodes used.Comment: 10th IEEE International Conference on Frontiers of Information Technology (FIT 12), 201