A Cost Analysis of Carpal Tunnel Release Surgery Performed Wide Awake versus under Sedation.

BACKGROUND: Hand surgery under local anesthesia only has been used more frequently in recent years. The purpose of this study was to compare perioperative time and cost for carpal tunnel release performed under local anesthesia ( wide-awake local anesthesia no tourniquet, or WALANT) only to carpal tunnel release performed under intravenous sedation. METHODS: A retrospective comparison of intraoperative (operating room) surgical time and postoperative (postanesthesia care unit) time for consecutive carpal tunnel release procedures performed under both intravenous sedation and wide-awake local anesthesia was undertaken. All operations were performed by the same surgeon using the same mini-open surgical technique. A cost analysis was performed by means of standardized anesthesia billing based on base units, time, and conversion rates. RESULTS: There were no significant differences between the two groups in terms of total operative time, 28 minutes in the intravenous sedation group versus 26 minutes in the wide-awake local anesthesia group. Postanesthesia care unit times were significantly longer in the intravenous sedation group (84 minutes) compared to the wide-awake local anesthesia group (7 minutes). Depending on conversion rates used, a total of $139 to$432 was saved in each case performed with wide-awake local anesthesia by not using anesthesia services. In addition, a range of $1320 to$1613 was saved for the full episode of care, including anesthesia costs, operating room time, and postanesthesia care unit time for each patient undergoing wide-awake local anesthesia carpal tunnel release. CONCLUSION: Carpal tunnel release surgery performed with the wide-awake local anesthesia technique offers significant reduction in cost for use of anesthesia and postanesthesia care unit resources

Efficiency of spinal anesthesia versus general anesthesia for lumbar spinal surgery: a retrospective analysis of 544 patients.

BACKGROUND: Previous studies have shown varying results in selected outcomes when directly comparing spinal anesthesia to general in lumbar surgery. Some studies have shown reduced surgical time, postoperative pain, time in the postanesthesia care unit (PACU), incidence of urinary retention, postoperative nausea, and more favorable cost-effectiveness with spinal anesthesia. Despite these results, the current literature has also shown contradictory results in between-group comparisons. MATERIALS AND METHODS: A retrospective analysis was performed by querying the electronic medical record database for surgeries performed by a single surgeon between 2007 and 2011 using procedural codes 63030 for diskectomy and 63047 for laminectomy: 544 lumbar laminectomy and diskectomy surgeries were identified, with 183 undergoing general anesthesia and 361 undergoing spinal anesthesia (SA). Linear and multivariate regression analyses were performed to identify differences in blood loss, operative time, time from entering the operating room (OR) until incision, time from bandage placement to exiting the OR, total anesthesia time, PACU time, and total hospital stay. Secondary outcomes of interest included incidence of postoperative spinal hematoma and death, incidence of paraparesis, plegia, post-dural puncture headache, and paresthesia, among the SA patients. RESULTS: SA was associated with significantly lower operative time, blood loss, total anesthesia time, time from entering the OR until incision, time from bandage placement until exiting the OR, and total duration of hospital stay, but a longer stay in the PACU. The SA group experienced one spinal hematoma, which was evacuated without any long-term neurological deficits, and neither group experienced a death. The SA group had no episodes of paraparesis or plegia, post-dural puncture headaches, or episodes of persistent postoperative paresthesia or weakness. CONCLUSION: SA is effective for use in patients undergoing elective lumbar laminectomy and/or diskectomy spinal surgery, and was shown to be the more expedient anesthetic choice in the perioperative setting

Obstructive sleep apnea syndrome and perioperative complications: a systematic review of the literature.

Obstructive sleep apnea syndrome (OSAS) is a common sleep related breathing disorder. Its prevalence is estimated to be between 2% and 25% in the general population. However, the prevalence of sleep apnea is much higher in patients undergoing elective surgery. Sedation and anesthesia have been shown to increase the upper airway collapsibility and therefore increasing the risk of having postoperative complications in these patients. Furthermore, the majority of patients with sleep apnea are undiagnosed and therefore are at risk during the perioperative period. It is important to identify these patients so that appropriate actions can be taken in a timely fashion. In this review article, we will discuss the epidemiology of sleep apnea in the surgical population. We will also discuss why these patients are at a higher risk of having postoperative complications, with the special emphasis on the role of anesthesia, opioids, sedation, and the phenomenon of REM sleep rebound. We will also review how to identify these patients preoperatively and the steps that can be taken for their perioperative management

Inhalational or total intravenous anaesthesia: is total intravenous anaesthesia useful and are there economic benefits?

PURPOSE OF REVIEW: The comparison of inhalational and intravenous anaesthesia has been the subject of many controlled trials and meta-analyses. These reported diverse endpoints typically including measures of the speed and quality of induction of anaesthesia, haemodynamic changes, operating conditions, various measures of awakening, postoperative nausea and vomiting and discharge from the recovery area and from hospital as well as recovery of psychomotor function. In a more patient-focused Health Service, measures with greater credibility are overall patient satisfaction, time to return to work and long-term morbidity and mortality. In practice, studies using easier to measure proxy endpoints dominate - even though the limitations of such research are well known. RECENT FINDINGS: Recent study endpoints are more ambitious and include impact on survival from cancer and the possibility of differential neurotoxic impact on the developing brain and implications for neuro-behavioural performance. SUMMARY: Economic analysis of anaesthesia is complex and most published studies are naive, focusing on drug acquisition costs and facility timings, real health economics are much more difficult. Preferred outcome measures would be whole institution costs or the ability to reliably add an extra case to an operating list, close an operating room and reduce the number of operating sessions offered or permanently decrease staffing. Alongside this, however, potential long-term patient outcomes should be considered

Intraarticular Tramadol-Bupivacaine Combination Prolongs the Duration of Postoperative Analgesia After Outpatient Arthroscopic Knee Surgery

BACKGROUND: Intraarticular (IA) local anesthetics are often used for the management and prevention of pain after arthroscopic knee surgery. Recently, IA tramadol was also used for the management of these patients. However, the IA combination of local anesthetic and tramadol has not been evaluated in arthroscopic outpatients. Our primary aim in this study was to evaluate the analgesic effect of an IA combination of bupivacaine and tramadol when compared with each drug alone using visual analog scale (VAS) pain scores in patients undergoing day-care arthroscopic knee surgery. Additionally, we assessed analgesic demand. METHODS: Ninety ASA I/II patients undergoing arthroscopic partial meniscectomy, performed by a single surgeon under general anesthesia, were assigned in a randomized, double-blind manner into three groups: group B (n = 30) received 0.25% bupivacaine, group T (n = 30) received 100 mg tramadol, and group BT (n = 30) received 0.25% bupivacaine and 100 mg tramadol to a total volume of 20 mL by the IA route after surgery. Postoperative pain scores were measured on a VAS, at rest and on mobilization at 0.5, 1, 2, 4, 6, 8, 12, and 24 h. Duration of analgesia, the subsequent 24 h consumption of rescue analgesia, time to ambulation, and time to discharge were evaluated. In addition, the systemic side effects of the IA injected drugs were also assessed. RESULTS: The results showed significantly lower VAS pain scores in group BT (P << 0.1) when compared with groups T and B. Group BT had a later onset of postsurgical pain and longer time to first rescue analgesic than groups B and T. The 24 h consumption of analgesic was significantly less in group BT when compared with the other two groups (26.7% of the patients required rescue analgesia in group BT, whereas this number was 90% in group B and 86.7% in group T). In addition, time in hours to discharge and time to unassisted ambulation were significantly shorter in group BT when compared with groups T and B, and this was not associated with any detectable systemic effects. CONCLUSION: The IA admixture of tramadol 100 mg with bupivacaine 0.25% provides a pronounced prolongation of analgesia compared with either drug alone in patients undergoing day care arthroscopic knee surgery

Reduction of Urinary Tract Infection and Antibiotic Use after Surgery: A Controlled, Prospective, Before-After Intervention Study

Background. Urinary tract infection is the most frequent health care—associated complication. We hypothesized that the implementation of a multifaceted prevention strategy could decrease its incidence after surgery. Methods. In a controlled, prospective, before-after intervention trial with 1328 adult patients scheduled for orthopedic or abdominal surgery, nosocomial infection surveillance was conducted until hospital discharge. A multifaceted intervention including specifically tailored, locally developed guidelines for the prevention of urinary tract infection was implemented for orthopedic surgery patients, and abdominal surgery patients served as control subjects. Infectious and noninfectious complications, adherence to guidelines, and antibiotic use were monitored before and after the intervention and again 2 years later. Results. The incidence of urinary tract infection decreased from 10.4 to 3.9 episodes per 100 patients in the intervention group (incidence-density ratio, 0.41; 95% CI, 0.20-0.79; P = .004). Adherence to guidelines was 82.2%. Both the frequency and the duration of urinary catheterization decreased following the intervention. Recourse to antibiotic therapy after surgery dropped in the intervention group from 17.9 to 15.6 defined daily doses per 100 patient-days (P < .005) because of a reduced need for the treatment of urinary tract infection (P < .001). Follow-up after 2 years revealed a sustained impact of the strategy and a subsequent low use of antibiotics, consistent with stable adherence to guidelines (80.8%). Conclusions. A multifaceted prevention strategy can dramatically decrease postoperative urinary tract infection and contribute to the reduction of the overall use of antibiotics after surger

Use of Air Arthrograms to Aid in Joint Distraction During Hip Arthroscopic Surgery Decreases Postoperative Pain and Opioid Requirements.

BackgroundPositive-pressure air arthrography and venting of the hip capsule are techniques used to decrease the traction forces needed for joint distraction during hip arthroscopic surgery. Little is known about the effects that these techniques have on postoperative pain.HypothesisPositive-pressure air arthrography and venting during hip arthroscopic surgery will decrease patient-reported pain and narcotic requirements in the acute postoperative setting.Study designCohort study; Level of evidence, 3.MethodsA retrospective cohort analysis was conducted to analyze 35 patients who underwent positive-pressure air arthrography and venting to aid joint distraction during hip arthroscopic surgery versus a group with similar demographics, pathologies, and treatments who did not undergo air arthrography. Numeric pain rating scale (NPRS) scores and medication administration including narcotic and nonnarcotic analgesia in the postanesthesia care unit (PACU) were tracked and compared.ResultsThe maximum (7.17 vs 4.97, respectively), minimum (2.43 vs 1.09, respectively), and mean (5.15 vs 3.11, respectively) NPRS scores were all higher in the control group compared with the air arthrogram group (P &lt; .001, P = .007, and P &lt; .001, respectively). The administration of oral morphine equivalents (OMEs) during the PACU stay was significantly lower in the air arthrogram group, with a mean of 36.75 ± 11.37 OMEs, compared with 44.53 ± 16.06 OMEs in the control group (P = .023). There was no difference in postoperative nonopioid medications, such as ketorolac or acetaminophen, given between groups.ConclusionPatients undergoing hip arthroscopic surgery with air arthrography and venting used to aid distraction had significantly less postoperative pain and required a lower total dosage of opioids during their PACU stay when compared with patients who underwent hip arthroscopic surgery without air arthrography

Neuromuscular monitoring during anesthesia

Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/Open í sviðinuObjective: Muscle relaxants are very important in anesthetic practice but must be used with great care. Studies have shown that 17-40% of patients in postanesthesia care units (PACU) have residual muscle weakness. The purpose of this study was to evaluate whether the use of neuromuscular monitors during anesthesia could reduce the incidence of muscle weakness in the postoperative period. Materials and method: Eighty patients operated for laparoscopic cholecystectomy or lumbal disc prolapse given muscle relaxants during anesthesia were studied, randomly allocated to four groups. Fourty of these patients were monitored with neuromuscular monitor (TOF-guard") during anesthesia and the set point was a TOF-ratio of at least 70% before extubating the patients. Fourty patients were monitored by usual clinical signs (spontaneus breathing, cough and muscle movement). Twenty patients in each group were given vecuronium as muscle relaxant and 20 patients recieved pancuronium, again patients were randomly selected. In the PACU all patients were evaluated and the "5-sec headlift test" was used to find patients with muscle weakness. Hand grip strength was also measured before anesthesia and in the PACU. Glascow Coma Score (GCS) was used to evaluate if patients were too drowsy to co-operate and patients with GCS < 12 were excluded. Measurements were made after arrival to the PACU and every 30 minutes thereafter until headlift was at least 5 sec. Results: The incidence of restcurarization was 15% on arrival to the PACU. No statistically significant difference was found between those monitored with neuromuscular monitors and those that were not. Similarily no statistical difference was found between short acting neuromuscular blocking agents and longer acting agents. Conclusion: Although we didn t find any benefit from neuromuscular monitoring or using shorter acting drugs, the use of nervestimulators and short acting drugs is still recommended, especially for high risk patients. The generally accepted train-of-four (TOF-) ratio of 70% has been questioned by some authors, recommending a higher ratio (85%). Further studies using a higher TOF-ratio are therefore recommended.Tilgangur: Vöðvaslakandi lyf eru notuð við mikinn hluta svæfinga í dag. Æskilegt er að verkun þeirra sé horfin strax að svæfingu lokinni en kannanir hafa hins vegar sýnt að í 17-40% tilvika gæti áhrifa þeirra lengur. Tilgangur þessarar rannsóknar var að kanna hvort hægt væri að minnka eftirstöðvar vöðvaslökunar að svæfingu lokinni með nákvæmri vöktun með taugaörva meðan á svæfingu stendur og auka þannig öryggi sjúklinga eftir skurðaðgerðir. Efniviður og aðferðir: Valdir voru af handahófi 80 sjúklingar sem gengust undir skurðaðgerð á Sjúkrahúsi Reykjavíkur (nú Landspítali Fossvogi) þar sem vöðvaslökun var fyrirfram ákveðin. Helmingur sjúklinga (40 talsins) var vaktaður með taugaörva í svæfingu þar sem gefin eru fjögur væg rafstuð í röð (train-of-four, TOF) og fylgst með TOF-hlutfalli. Markmiðið var að TOF-hlutfall yrði að minnsta kosti 70% áður en sjúklingar væru vaktir og barkarenna fjarlægð. Hjá hinum 40 sjúklingunum var stuðst við klínísk einkenni, svo sem eigin öndun, hósta og vöðvahreyfingar til mats á vöðvaslökun. Tuttugu sjúklingar í hvorum hópi fengu vöðvaslakandi lyfið vecúróníum sem hefur miðlungslanga verkun og 20 sjúklingar fengu langverkandi lyfið pancúróníum. Eftirstöðvar vöðvaslökunar voru metnar á vöknunardeild með svokallaðri "fimm sekúndna höfuðlyftu" en hún er talin vera það klíníska próf sem best gefur til kynna hvort sjúklingur hafi endurheimt nægjanlegan vöðvastyrk til að halda öndunarvegi opnum og hreinum. Handstyrkur sjúklings var einnig mældur fyrir og eftir svæfingu. Þeir sjúklingar sem voru lægri en 12 samkvæmt Glasgow meðvitundarkvarða (Glasgow Coma Score, GCS) og því hugsanlega of sljóir eftir svæfinguna til að taka þátt í prófununum voru ekki teknir með fyrr en GCS var komið yfir 12 stig. Niðurstöður: Í ljós kom að 15% sjúklinga voru undir áhrifum vöðvaslakandi lyfja við komu á vöknunardeild. Sjúklingahóparnir voru sambærilegir varðandi almenn atriði, svo sem aldur, kyn, þyngd og blóðgildi. Notkun taugaörva með TOF-hlutfalli 70% reyndist ekki marktækt fækka sjúklingum með einkenni um vöðvaslökun eftir svæfingu. Munur á lyfjum með langa eða miðlungslanga verkun með tilliti til eftirstöðva vöðvaslökunar reyndist heldur ekki marktækur. Ályktun: Eftirstöðvar af áhrifum vöðvaslakandi lyfja eru nokkuð algengar (15%) hjá sjúklingum við komu á vöknunardeild. Hvorki notkun stuttverkandi lyfja né notkun fullkomins taugaörva fækkaði marktækt sjúklingum með minnkaðan vöðvastyrk eftir svæfingu en þó teljum við ástæðu til að mæla áfram með vöktun vöðvaslökunar, ekki síst við svæfingar áhættusjúklinga og í löngum aðgerðum. Til þessa hefur verið talið að 70% TOF-hlutfall nægði til þess að sjúklingurinn hefði nægilegan vöðastyrk í lok svæfingar. Nýleg rannsókn bendir hins vegar til þess að TOF-hlutfall þurfi að vera að minnsta kosti 85% til að fyrirbyggja eftirstöðvar vöðvaslökunar. Frekari rannsókna er þörf þar sem markmiðið væri hærra TOF-hlutfall

Sugammadex for reversal of neuromuscular blockade: A retrospective analysis of clinical outcomes and cost-effectiveness in a single center

OBJECTIVE: The aim of the study is to evaluate the clinical and economic impact of introducing a rocuronium-neostigmine-sugammadex strategy into a cisatracurium-neostigmine regimen for neuromuscular block (NMB) management. METHODS: We conducted a retrospective analysis of clinical outcomes and cost-effectiveness in five operating rooms at University Hospital of Padova. A clinical outcome evaluation after sugammadex administration as first-choice reversal drug in selected patients (rocuronium-sugammadex) and as rescue therapy after neostigmine reversal (rocuronium-neostigmine-sugammadex) compared to control was performed. A cost-analysis of NMB management accompanying the introduction of a rocuronium-neostigmine-sugammadex strategy into a cisatracurium-neostigmine regimen was carried out. To such purpose, two periods were compared: 2011-2012, without sugammadex available; 2013-2014, with sugammadex available. A subsequent analysis was performed to evaluate if sugammadex replacing neostigmine as first choice reversal drug is cost-effective. RESULTS: The introduction of a rocuronium-neostigmine-sugammadex strategy into a cisatracurium-neostigmine regimen reduced the average cost of NMB management by 36%, from €20.8/case to €13.3/case. Patients receiving sugammadex as a first-choice reversal drug (3%) exhibited significantly better train-of-four ratios at extubation (P<0.001) and were discharged to the surgical ward (P<0.001) more rapidly than controls. The cost-saving of sugammadex as first-choice reversal drug has been estimated to be €2.9/case. Patients receiving sugammadex as rescue therapy after neostigmine reversal (3.2%) showed no difference in time to discharge to the surgical ward (P=0.44) compared to controls. No unplanned intensive care unit (ICU) admissions with rocuronium-neostigmine-sugammadex strategy were observed. The potential economic benefit in avoiding postoperative residual curarization (PORC)-related ICU admission in the 2013-2014 period was estimated at an average value of €13,548 (€9,316-€23,845). CONCLUSION: Sugammadex eliminated PORC and associated morbidities. In our center, sugammadex reduced the costs of NMB management and promoted rapid turnover of patients in operating rooms, with total cost-effectiveness that counteracts the disadvantages of its high cost

Sterile acellular dermal collagen as a treatment for rippling deformity of breast.

Prosthetic implants are frequently used for breast augmentation and breast reconstruction following mastectomy. Unfortunately, long-term aesthetic results of prosthetic breast restoration may be hindered by complications such as rippling, capsular contracture, and implant malposition. The advent of use of acellular dermal matrices has greatly improved the outcomes of prosthetic breast reconstruction. We describe a case of rippling deformity of breast that was treated using an acellular dermal matrix product, AlloMax. The patient presented with visible rippling of bilateral prosthetic breast implants as well as significant asymmetry of the breasts after multiple excisional biopsies for right breast ductal carcinoma in situ. A 6 × 10 cm piece of AlloMax was placed on the medial aspect of each breast between the implant and the skin flap. Follow-up was performed at 1 week, 3 months, and 1 year following the procedure. The patient recovered well from the surgery and there were no complications. At her first postoperative follow-up the patient was extremely satisfied with the result. At her 3-month and 1-year follow-up she had no recurrence of her previous deformity and no new deformity