A new combination in Chionoloma Dix. (Musci, Pottiaceae)

After publication of the partial revision of Symblepharis Broth., Asian material (Sollman 2000), I came to realize that a new combination in Chionoloma Dix. is necessary; see especially mewnzel (1992)

Generic homonyms in the Colydiinae (Coleoptera: Zopheridae)

New replacement names are proposed: Megapnosaurus Ivie, Slipinski and Wegrzynowicz NEW REPLACEMENT NAME for Syntarsus Raath 1969 (Ceratosauria: Coelophysidae), not Syntarsus Fairmaire 1869 (Coleoptera: Zopheridae: Colydiinae); and Stephaniolus Ivie, Slipinski and Wegrzynowicz NEW REPLACEMENT NAME for Pseudotaphrus Stephan 1989 (Coleoptera: Zopheridae: Colydiinae) not Pseudotaphrus Cossmann 1888 (Mollusca: Rissoiidae). These result in the new combinations Megapnosaurus rhodesiensis (Raath 1961) NEW COMBINATION, Megapnosaurus kayentalwtae (Rowe 1989) NEW COMBINATION and Stephanioh£s longus (Stephan 1989) NEW COMBINATION

South American Melolonthinae (Coleoptera: Scarabaeidae) classification and nomenclature: some problems and solutions

Classificatory changes are made for some taxa of New World Melolonthinae based on the examination of specimens (including type specimens) and a reevaluation of some of the characters used to justify previous classification decisions. Blepharotoma angustata (Blanchard) (new combination) is transferred from the genus Aplodema Blanchard. The Neotropical members of the genus Heteronyx Guérin-Méneville are transferred to the genus Blepharotoma resulting in the following new combinations: Blepharotoma boliviana (Moser), Blepharotoma corumbana (Moser), Blepharotoma cuyabana (Moser), Blepharotoma heynei (Moser), and Blepharotoma schencklingi (Moser). The genus Blepharotoma is transferred from the tribe Liparetrini to the tribe Sericoidini. The genus Aplodema and the junior synonym Haplodema Harold are transferred from the tribe Liparetrini to the tribe Sericoidini and synonymized with the genus Sericoides Guérin-Méneville. Sericoides magellanica (Blanchard) (new combination) is transferred from the genus Aplodema and placed as a senior synonym of Apterodema acuticollis Fairmaire (new synonymy). Ampliodactylus (new genus) is described for two southern South American species: Ampliodactylus marmoratus (Curtis) (new combination) and Ampliodactylus vestitus (Philippi) (new combination). The genus Chremastodus Solier is placed in synonymy with the genus Macrodactylus Dejean (Macrodactylini) and Chremastodus pubescens Solier is placed as a junior synonym of Macrodactylus chilensis Solier (new synonymy). Macrodactylus crassipes Philippi and Macrodactylus nigrinus Philippi are placed as junior synonyms of Macrodactylus farinosus Philippi (new synonymies). The genus Astaenosiagum Martínez is placed in synonymy with the genus Pristerophora Harold (Macrodactylini). Pristerophora longipes (Philippi) (new combination) is transferred from the genus Astaenosiagum and Schizochelus ursulus Philippi is placed as a junior synonym of this species (new synonymy). Pristerophora paulseni (new species) is described. Pristerophora picipennis (Solier) is placed as a senior synonym of Schizochelus breviventris Philippi (new synonymy) and Schizochelus serratus Philippi (new synonymy). Pusiodactylus (new genus) is described for two southern South American species: Pusiodactylus mondacai (new species) and Pusiodactylus flavipennis (Philippi) (new combination). The genus Paulosawaya Martínez and D'Andretta is placed in synonymy with the genus Clavipalpus Laporte (Macrodactylini) resulting in the new combination Clavipalpus ornatissima (Martínez and D'Andretta). The following replacement names are proposed for three junior secondary homonyms the genus Plectris LePeletier and Serville: Plectris evansi (new name) for Plectris cinerascens Moser (junior secondary homonym of Plectris cinerascens (Blanchard)), Plectris katovichi (new name) for Plectris bonariensis Frey (junior secondary homonym of Plectris bonariensis (Bruch)), and Plectris tacoma (new name) for Plectris comata (Blanchard) (junior secondary homonym of Plectris comata (Blanchard))

A new realization of rational functions, with applications to linear combination interpolation

We introduce the following linear combination interpolation problem (LCI): Given $N$ distinct numbers $w_1,\ldots w_N$ and $N+1$ complex numbers $a_1,\ldots, a_N$ and $c$, find all functions $f(z)$ analytic in a simply connected set (depending on $f$) containing the points $w_1,\ldots,w_N$ such that $$\sum_{u=1}^Na_uf(w_u)=c.$$ To this end we prove a representation theorem for such functions $f$ in terms of an associated polynomial $p(z)$. We first introduce the following two operations, $(i)$ substitution of $p$, and $(ii)$ multiplication by monomials $z^j, 0\le j < N$. Then let $M$ be the module generated by these two operations, acting on functions analytic near $0$. We prove that every function $f$, analytic in a neighborhood of the roots of $p$, is in $M$. In fact, this representation of $f$ is unique. To solve the above interpolation problem, we employ an adapted systems theoretic realization, as well as an associated representation of the Cuntz relations (from multi-variable operator theory.) We study these operations in reproducing kernel Hilbert space): We give necessary and sufficient condition for existence of realizations of these representation of the Cuntz relations by operators in certain reproducing kernel Hilbert spaces, and offer infinite product factorizations of the corresponding kernels

Compressive Diffusion Strategies Over Distributed Networks for Reduced Communication Load

We study the compressive diffusion strategies over distributed networks based on the diffusion implementation and adaptive extraction of the information from the compressed diffusion data. We demonstrate that one can achieve a comparable performance with the full information exchange configurations, even if the diffused information is compressed into a scalar or a single bit. To this end, we provide a complete performance analysis for the compressive diffusion strategies. We analyze the transient, steady-state and tracking performance of the configurations in which the diffused data is compressed into a scalar or a single-bit. We propose a new adaptive combination method improving the convergence performance of the compressive diffusion strategies further. In the new method, we introduce one more freedom-of-dimension in the combination matrix and adapt it by using the conventional mixture approach in order to enhance the convergence performance for any possible combination rule used for the full diffusion configuration. We demonstrate that our theoretical analysis closely follow the ensemble averaged results in our simulations. We provide numerical examples showing the improved convergence performance with the new adaptive combination method.Comment: Submitted to IEEE Transactions on Signal Processin

Epi-drugs in combination with immunotherapy: a new avenue to improve anticancer efficacy

Immune checkpoint factors, such as programmed cell death protein-1/2 (PD-1, PD-2) or cytotoxic T lymphocyte-associated antigen-4 (CTLA-4) receptors, are targets for monoclonal antibodies (MAbs) developed for cancer immunotherapy. Indeed, modulating immune inhibitory pathways has been considered an important breakthrough in cancer treatment. Although immune checkpoint blockade therapy used to treat malignant diseases has provided promising results, both solid and haematological malignancies develop mechanisms that enable themselves to evade the host immune system. To overcome some major limitations and ensure safety in patients, recent strategies have shown that combining epigenetic modulators, such as inhibitors of histone deacetylases (HDACi) or DNA methyltransferases (DNMTi), with immunotherapeutics can be useful. Preclinical data generated using mouse models strongly support the feasibility and effectiveness of the proposed approaches. Indeed, co-treatment with pan- or class I-selective HDACi or DNMTi improved beneficial outcomes in both in vitro and in vivo studies. Based on the evidence of a pivotal role for HDACi and DNMTi in modulating various components belonging to the immune system, recent clinical trials have shown that both HDACi and DNMTi strongly augmented response to anti-PD-1 immunotherapy in different tumour types. This review describes the current strategies to increase immunotherapy responses, the effects of HDACi and DNMTi on immune modulation, and the advantages of combinatorial therapy over single-drug treatment

Direct combination: a new user interaction principle for mobile and ubiquitous HCI

Direct Combination (DC) is a recently introduced user interaction principle. The principle (previously applied to desktop computing) can greatly reduce the degree of search, time, and attention required to operate user interfaces. We argue that Direct Combination applies particularly aptly to mobile computing devices, given appropriate interaction techniques, examples of which are presented here. The reduction in search afforded to users can be applied to address several issues in mobile and ubiquitous user interaction including: limited feedback bandwidth; minimal attention situations; and the need for ad-hoc spontaneous interoperation and dynamic reconfiguration of multiple devices. When Direct Combination is extended and adapted to fit the demands of mobile and ubiquitous HCI, we refer to it as Ambient Combination (AC) . Direct Combination allows the user to exploit objects in the environment to narrow down the range of interactions that need be considered (by system and user). When the DC technique of pairwise or n-fold combination is applicable, it can greatly lessen the demands on users for memorisation and interface navigation. Direct Combination also appears to offers a new way of applying context-aware information. In this paper, we present Direct Combination as applied ambiently through a series of interaction scenarios, using an implemented prototype system