Standard operating procedures (SOP) in experimental stroke research: SOP for middle cerebral artery occlusion in the mouse

Recently, systematic reviews have found quantitative evidence that low study quality may have introduced a bias into preclinical stroke research. Monitoring, auditing, and standard operating procedures (SOPs) are already key elements of quality control in randomized clinical trials and will hopefully be widely adopted by preclinical stroke research in the near future. Increasingly, funding bodies and review boards overseeing animal experiments are taking a proactive stance, and demand auditable quality control measures in preclinical research. Every good quality control system is based on its SOPs. This article introduces the concept of quality control and presents for the first time an SOP in experimental stroke research

UCL (University College London) Libraries Masterplan: Library Report to Estates Management Committee January 2008

This document is a Report from UCL Library Services to UCL on Master Planning activities and outputs which have been undertaken to quantify use and development of estate in UCL Library Services. Prioritised options have been identified for the UCL Main and Science Libraries, and for a new central site option. This work has also addressed the needs of UCL for long-term offsite storage, which concludes that UCL needs to retain its facility at Wickford for at least the next ten years

Advisory Board Members

For SSHRC funded projects, the Applicant, now Principal Investigator (PI), has responsibility for the direction of the project and all financial expenditures. Consistent with this requirement, the CBERN/SSHRC proposal contains two Governance elements. First, the Principal Investigator is required to report to an annual meeting whose membership includes co-applicants, now co-investigators, collaborators and partners, on financial expenditures, project activities and strategic planning. In addition, the proposal calls for the establishment of an Advisory Board, which is to meet at least twice yearly, in person at the Annual Meeting and by telephone conference mid-way through the year. Initial membership and structure of the Advisory Board was set out in the proposal

Spare capacity modelling and its applications in survivable iP-over-optical networks

As the interest in IP-over-optical networks are becoming the preferred core network architecture, survivability has emerged as a major concern for network service providers; a result of the potentially huge traffic volumes that will be supported by optical infrastructure. Therefore, implementing recovery strategies is critical. In addition to the traditional recovery schemes based around protection and restoration mechanisms, pre-allocated restoration represents a potential candidate to effect and maintain network resilience under failure conditions. Preallocated restoration technique is particularly interesting because it provides a trade-off in terms of recovery performance and resources between protection and restoration schemes. In this paper, the pre-allocated restoration performance is investigated under single and dual-link failures considering a distributed GMPLSbased IP/WDM mesh network. Two load-based spare capacity optimisation methods are proposed in this paper; Local Spare Capacity Optimisation (LSCO) and Global Spare Capacity Optimisation (GSCO)