Quantum Imaging Technologies

Over the past three decades, quantum mechanics has allowed the development of technologies that provide unconditionally secure communication. In parallel, the quantum nature of the transverse electromagnetic field has spawned the field of quantum imaging that encompasses technologies such as quantum ghost imaging and high-dimensional quantum key distribution (QKD). The emergence of such quantum technologies also highlights the need for the development of methods for characterizing the elusive quantum state itself. In this document, we describe new technologies that use the quantum properties of light for security. The first is a technique that extends the principles behind QKD to the field of imaging. By applying the polarization-based BB84 protocol to individual photons in an active imaging system, we obtained images that are secure against intercept-resend jamming attacks. The second technology presented in this article is based on an extension of quantum ghost imaging. We used a holographic filtering technique to build a quantum ghost image identification system that uses a few pairs of photons to identify an object from a set of known objects. The third technology addressed in this document is a high-dimensional QKD system that uses orbital-angular-momentum (OAM) modes of light for encoding. Moving to a high-dimensional state space in QKD allows one to impress more information on each photon, as well as introduce higher levels of security. We discuss the development of two OAM-QKD protocols based on the BB84 and Ekert QKD protocols. The fourth and final technology presented in this article is a relatively new technique called direct measurement that uses sequential weak and strong measurements to characterize a quantum state. We use this technique to characterize the quantum state of a photon with a dimensionality of d=27, and measure its rotation in the natural basis of OAM.Comment: 63 pages, 37 figure

Real applications of quantum imaging

In the last years the possibility of creating and manipulating quantum states of light has paved the way to the development of new technologies exploiting peculiar properties of quantum states, as quantum information, quantum metrology & sensing, quantum imaging ... In particular Quantum Imaging addresses the possibility of overcoming limits of classical optics by using quantum resources as entanglement or sub-poissonian statistics. Albeit quantum imaging is a more recent field than other quantum technologies, e.g. quantum information, it is now substantially mature for application. Several different protocols have been proposed, some of them only theoretically, others with an experimental implementation and a few of them pointing to a clear application. Here we present a few of the most mature protocols ranging from ghost imaging to sub shot noise imaging and sub Rayleigh imaging.Comment: REVIEW PAPE

Novel Retinal Imaging Technologies

Newly-developed imaging techniques show extensive promise and potential to improve early detection, accurate diagnosis, and management of retinal diseases. Optical coherernce tomography angiography (OCTA), photoacoustic imaging (PAI), and molecular imaging (MI) are all new and promising imaging modalities. As these imaging instruments have advanced, they have enabled visualization of the retina at an unprecedented resolution. Published studies have established the efficacy of these modalities in the assessment of common retinal diseases, such as age-related macular degeneration, diabetic retinopathy, and retinal vascular occlusions. Each of these systems is built upon different principles and all have different limitations. In addition, the three imaging modalities have complementary features and thus can be integrated in to a multimodal imaging system, which will be more powerful in future

Advances in infrared and imaging fibres for astronomical instrumentation

Optical fibres have already played a huge part in ground based astronomical instrumentation, however, with the revolution in photonics currently taking place new fibre technologies and integrated optical devices are likely to have a profound impact on the way we manipulate light in the future. The Anglo-Australian Observatory, along with partners at the Optical Fibre Technology Centre of the University of Sydney, is investigating some of the developing technologies as part of our Astrophotonics programme. In this paper we discuss the advances that have been made with infrared transmitting fibre, both conventional and microstructured, in particular those based on flouride glasses. Flouride glasses have a particularly wide transparent region from the UV through to around 7um, whereas silica fibres, commonly used in astronomy, only transmit out to about 2um. We discuss the impact of advances in fibre manufacture that have greatly improved the optical, chemical resistance and physical properties of the flouride fibres. We also present some encouraging initial test results for a modern imaging fibre bundle and imaging fibre taper.Comment: 11 pages, 7 figures, to be published in Proc. SPIE 6273 Optomechanical Technologies for Astronom

Development and characterisation of an easily configurable range imaging system

Range imaging is becoming a popular tool for many applications, with several commercial variants now available. These systems find numerous real world applications such as interactive gaming and the automotive industry. This paper describes the development of a range imaging system employing the PMD-19 k sensor from PMD technologies. One specific advantage of our system is that it is extremely customisable in terms of modulation patterns to act as a platform for further research into time-of-flight range imaging. Experimental results are presented giving an indication of the precision and accuracy of the system, and how modifying certain operating parameters can improve system performance

Simultaneous in vivo positron emission tomography and magnetic resonance imaging

Positron emission tomography (PET) and magnetic resonance imaging (MRI) are widely used in vivo imaging technologies with both clinical and biomedical research applications. The strengths of MRI include high-resolution, high-contrast morphologic imaging of soft tissues; the ability to image physiologic parameters such as diffusion and changes in oxygenation level resulting from neuronal stimulation; and the measurement of metabolites using chemical shift imaging. PET images the distribution of biologically targeted radiotracers with high sensitivity, but images generally lack anatomic context and are of lower spatial resolution. Integration of these technologies permits the acquisition of temporally correlated data showing the distribution of PET radiotracers and MRI contrast agents or MR-detectable metabolites, with registration to the underlying anatomy. An MRI-compatible PET scanner has been built for biomedical research applications that allows data from both modalities to be acquired simultaneously. Experiments demonstrate no effect of the MRI system on the spatial resolution of the PET system and <10% reduction in the fraction of radioactive decay events detected by the PET scanner inside the MRI. The signal-to-noise ratio and uniformity of the MR images, with the exception of one particular pulse sequence, were little affected by the presence of the PET scanner. In vivo simultaneous PET and MRI studies were performed in mice. Proof-of-principle in vivo MR spectroscopy and functional MRI experiments were also demonstrated with the combined scanner

The current state of biomarker research for Friedreich's ataxia: a report from the 2018 FARA biomarker meeting

The 2018 FARA Biomarker Meeting highlighted the current state of development of biomarkers for Friedreich's ataxia. A mass spectroscopy assay to sensitively measure mature frataxin (reduction of which is the root cause of disease) is being developed. Biomarkers to monitor neurological disease progression include imaging, electrophysiological measures and measures of nerve function, which may be measured either in serum and/or through imaging-based technologies. Potential pharmacodynamic biomarkers include metabolic and protein biomarkers and markers of nerve damage. Cardiac imaging and serum biomarkers may reflect cardiac disease progression. Considerable progress has been made in the development of biomarkers for various contexts of use, but further work is needed in terms of larger longitudinal multisite studies, and identification of novel biomarkers for additional use cases

Optical Hyperlens: Far-field imaging beyond the diffraction limit

We propose an approach to far-field optical imaging beyond the diffraction limit. The proposed system allows image magnification, is robust with respect to material losses and can be fabricated by adapting existing metamaterial technologies in a cylindrical geometry