Diagnostic error reduction in the United States and Italy through the intervention of diagnostic management teams

A major challenge to most countries is the growing cost of healthcare. The cost of laboratory testing is approximately 3% of the total clinical costs. On the other hand, waste from inappropriate admissions to clinical departments is reported to be as high as 15%. A frequently used approach to save dollars in healthcare is the random reduction in the budget for laboratories, with a focus on reduction of the number of unnecessary laboratory tests. The World Health Assembly has approached the problem by publishing a list of essential in vitro diagnostic tests, in order to achieve a global rationalization of the problem. A much more thoughtful strategy to saving healthcare finance is to improve the efficiency of the diagnostic process. This report presents an opportunity to reduce diagnostic error and increase the efficiency of diagnostic testing. Reduction in time to a correct diagnosis provides a major financial as well as a clinical benefit. In addition, reducing both overutilization and underutilization of laboratory tests while achieving the correct diagnosis is a major benefit to challenged healthcare budgets. One approach taken to achieve major savings in healthcare has been the creation of “Diagnostic Management Teams,” composed of experts in specialty areas of medicine who are primarily based in the clinical laboratory to advise physicians on the selection of only necessary tests and the interpretation of complex test results

The Squared-Error of Generalized LASSO: A Precise Analysis

We consider the problem of estimating an unknown signal $x_0$ from noisy linear observations $y = Ax_0 + z\in R^m$. In many practical instances, $x_0$ has a certain structure that can be captured by a structure inducing convex function $f(\cdot)$. For example, $\ell_1$ norm can be used to encourage a sparse solution. To estimate $x_0$ with the aid of $f(\cdot)$, we consider the well-known LASSO method and provide sharp characterization of its performance. We assume the entries of the measurement matrix $A$ and the noise vector $z$ have zero-mean normal distributions with variances $1$ and $\sigma^2$ respectively. For the LASSO estimator $x^*$, we attempt to calculate the Normalized Square Error (NSE) defined as $\frac{\|x^*-x_0\|_2^2}{\sigma^2}$ as a function of the noise level $\sigma$, the number of observations $m$ and the structure of the signal. We show that, the structure of the signal $x_0$ and choice of the function $f(\cdot)$ enter the error formulae through the summary parameters $D(cone)$ and $D(\lambda)$, which are defined as the Gaussian squared-distances to the subdifferential cone and to the $\lambda$-scaled subdifferential, respectively. The first LASSO estimator assumes a-priori knowledge of $f(x_0)$ and is given by $\arg\min_{x}\{{\|y-Ax\|_2}~\text{subject to}~f(x)\leq f(x_0)\}$. We prove that its worst case NSE is achieved when $\sigma\rightarrow 0$ and concentrates around $\frac{D(cone)}{m-D(cone)}$. Secondly, we consider $\arg\min_{x}\{\|y-Ax\|_2+\lambda f(x)\}$, for some $\lambda\geq 0$. This time the NSE formula depends on the choice of $\lambda$ and is given by $\frac{D(\lambda)}{m-D(\lambda)}$. We then establish a mapping between this and the third estimator $\arg\min_{x}\{\frac{1}{2}\|y-Ax\|_2^2+ \lambda f(x)\}$. Finally, for a number of important structured signal classes, we translate our abstract formulae to closed-form upper bounds on the NSE

Statistical mechanics of error exponents for error-correcting codes

Error exponents characterize the exponential decay, when increasing message length, of the probability of error of many error-correcting codes. To tackle the long standing problem of computing them exactly, we introduce a general, thermodynamic, formalism that we illustrate with maximum-likelihood decoding of low-density parity-check (LDPC) codes on the binary erasure channel (BEC) and the binary symmetric channel (BSC). In this formalism, we apply the cavity method for large deviations to derive expressions for both the average and typical error exponents, which differ by the procedure used to select the codes from specified ensembles. When decreasing the noise intensity, we find that two phase transitions take place, at two different levels: a glass to ferromagnetic transition in the space of codewords, and a paramagnetic to glass transition in the space of codes.Comment: 32 pages, 13 figure

Error Analysis on Learners' Interlanguage and Intralanguage: a Case Study of Two Adolescent Students

This research focuses on exploring learners' language, especially the errors that are performed by the English learners. The subjects of this study are two adolescent students who have been learning English since early age. The data analyzed is collected by doing the interview session. Identification and classification are done toward the errors performed by the subjects. After that, the pattern is drawn to find out the subjects' nature of language. The result shows that both interlanguage and intralanguage affect the students' English. However, interlanguage affects the errors more than does intralanguage. It proves that the nature of L1 affects the L2 acquisition. The errors occurred in terms of subject-verb agreement, tenses, and relative clause. At the end, the appropriate feedback given to speaking performance is implicit correction such as recast and prompts

Counter-(T)error

Traditionally immigrants have been made responsible for a rise in a country’s crime rate, a state’s employment market or a nation’s cultural identity. However, since the events of 9/11 immigrants have evolved into a new kind of security concern. As a result of the terrorist attacks in 2001 by nineteen foreigners, the issue of immigration has become a central aspect in counter-terrorism as nations around the world scrambled to implement policies in reaction to the unprecedented situation. However, one has to question the validity and effectiveness of using immigration measures in the fight against terrorism. Is there an error in current counter-terror policies? The paper will critically discuss whether immigration policies are a useful means of addressing the global threat of terrorism

Grammatical Error Analysis of Student's Comment Writing Based on Facebook Game in English Intensive Class of Stain Jurai Siwo Metro 2013

This paper is titled “Grammatical Error Analysis of Students' Comment Writing Based on Facebook Game in English Intensive Class of STAIN JURAI SIWO METRO 2013”. The aim of this research is to describe grammatical errors which are made by the students of English Intensive Class. It is a qualitative-descriptive research. The data are taken from the result of students‟ comment writing on Facebook game in English intensive class. Meanwhile, the techniques to collect the data used note and observation. The result is displayed in words. The research shows that the grammatical errors made by the students in English intensive class are using double auxiliary, confusing to apply nominal or verbal sentence, and making error interrogative form pattern

Zero Error Coordination

In this paper, we consider a zero error coordination problem wherein the nodes of a network exchange messages to be able to perfectly coordinate their actions with the individual observations of each other. While previous works on coordination commonly assume an asymptotically vanishing error, we assume exact, zero error coordination. Furthermore, unlike previous works that employ the empirical or strong notions of coordination, we define and use a notion of set coordination. This notion of coordination bears similarities with the empirical notion of coordination. We observe that set coordination, in its special case of two nodes with a one-way communication link is equivalent with the "Hide and Seek" source coding problem of McEliece and Posner. The Hide and Seek problem has known intimate connections with graph entropy, rate distortion theory, Renyi mutual information and even error exponents. Other special cases of the set coordination problem relate to Witsenhausen's zero error rate and the distributed computation problem. These connections motivate a better understanding of set coordination, its connections with empirical coordination, and its study in more general setups. This paper takes a first step in this direction by proving new results for two node networks