1 research outputs found
Extending the pool of compatible peptide hydrogels for protein crystallization
Short-peptide supramolecular (SPS) hydrogels are a class of materials that have been found
to be useful for (bio)technological applications thanks to their biocompatible nature. Among the
advantages reported for these peptides, their economic a ordability and easy functionalization or
modulation have turned them into excellent candidates for the development of functional biomaterials.
We have recently demonstrated that SPS hydrogels can be used to produce high-quality protein
crystals, improve their properties, or incorporate relevant materials within the crystals. In this work,
we prove that hydrogels based on methionine and tyrosine are also good candidates for growing
high-quality crystals of the three model proteins: lysozyme, glucose isomerase, and thaumatin.This study was supported by projects BIO2016-74875-P and FIS2017-85954-R (Ministerio de Economía,
Industria y Competitividad, MINECO, and Agencia Estatal de Investigación, AEI, Spain, cofunded by Fondo
Europeo de Desarrollo Regional, FEDER, European Union)