Determining the polarity of postings for discussion search

When performing discussion search it might be desirable to consider non-topical measures like the number of positive and negative replies to a posting, for instance as one possible indicator for the trustworthiness of a comment. Systems like POLAR are able to integrate such values into the retrieval function. To automatically detect the polarity of postings, they need to be classified into positive and negative ones w.r.t.\ the comment or document they are annotating. We present a machine learning approach for polarity detection which is based on Support Vector Machines. We discuss and identify appropriate term and context features. Experiments with ZDNet News show that an accuracy of around 79\%-80\% can be achieved for automatically classifying comments according to their polarity

Determine supporting features for mobile application of NUSANTARA

This paper is a continuation of previous research focusing on the development of a model of knowledge management system for civil servant from three ministries in Indonesia (KEMENPAN&RB, BKN, and LAN). From previous study obtain a knowledge management model which is Government Human Capital Knowledge Management of Republic of Indonesia (NUSANTARA). Implementation of this model is conducted with web system, further development of this system still provides constraints from several sides in providing more optimal service against users requirements as well as limited accessibility and responsiveness. This paper aims to explore the supporting features that will be used to integrate pre- existing systems that build mobile knowledge management applications. Data were collected by interview from each related institution. The CommonKADS method is chosen as a technique to explore the problems and knowledge of each organization. SMAPA method is used to validate the result from the experts and end users. Results of this work are produced seven recommended supporting features there are vision and mission view, activity notification, group discussion, search repository, upload document and document activities log

Structure and function prediction of human homologue hABH5 of _E. coli_ ALKB5 using in silico approach

Newly discovered human homologues of ALKB protein have shown the activity of DNA damaging drugs, used for cancer therapy. Little is known about the structure and function of hABH5, one of the members of this superfamily. Therefore, in the present study we intend to predict its structure and function using various bioinformatics tools. Modeling was done with modeler 9v7 to predict the 3D structure of the hABH5 protein. 3-D model of hABH5, ALKBH5.B99990005.pdb was predicted and evaluated. Validation results showed 96.8% residues in favor and an additional allowed region of the Ramachandran plot. Ligand binding residues prediction showed four ligand clusters, having 25 ligands in cluster 1. Importantly, conserved pattern of Pro158-X-Asp160-Xn-His266 in the functional domain was detected. DNA and RNA binding sites were also predicted in the model. The predicted and validated model of human homologue hABH5 resulting from this study may unveil the mechanism of DNA damage repair in humans and accelerate research on designing appropriate inhibitors, aiding in chemotherapy and cancer related diseases

Structure and function prediction of human homologue hABH5 of _E. coli_ ALKB5 using in silico approach

Newly discovered human homologues of ALKB protein have shown the activity of DNA damaging drugs, used for cancer therapy. Little is known about the structure and function of hABH5, one of the members of this superfamily. Therefore, in the present study we intend to predict its structure and function using various bioinformatics tools. Modeling was done with modeler 9v7 to predict the 3D structure of the hABH5 protein. 3-D model of hABH5, ALKBH5.B99990005.pdb was predicted and evaluated. Validation results showed 96.8% residues in favor and an additional allowed region of the Ramachandran plot. Ligand binding residues prediction showed four ligand clusters, having 25 ligands in cluster 1. Importantly, conserved pattern of Pro158-X-Asp160-Xn-His266 in the functional domain was detected. DNA and RNA binding sites were also predicted in the model. The predicted and validated model of human homologue hABH5 resulting from this study may unveil the mechanism of DNA damage repair in humans and accelerate research on designing appropriate inhibitors, aiding in chemotherapy and cancer related diseases

Molecular modelling and Function Prediction of hABH7, human homologue of _E. coli_ ALKB7

Human homologues of ALKB protein have shown the prime role in DNA damaging drugs, used for cancer therapy. Little is known about structure and function of hABH7, one of the members of this superfamily. Therefore, in the present study we intend to predict its structure and function using various bioinformatics tools. Modeling was done with modeller 9v7 to predict the 3D structure of the hABH7 protein. The tertiary structure model of hABH7, ALKBH7.B99990002.pdb was predicted and evaluated. Validation results showed 97.8% residues in favored and additional allowed regions of Ramachandran plots. Ligand binding residues prediction showed four ligand clusters, having 25 ligands in cluster 1. Importantly, presence of a Phe120-Gly121-Gly122 conserved pattern in the functional domain was detected. In the predicted structural model of hABH7, amino acid residues, Arginine at 57, 58, 59 and 60 along with tyrosine at 61 were predicted in RNA binding sites of the model. The predicted and validated model of human homologue hABH7 resulting from this study may unveil the mechanism of DNA damage repair in humans and accelerate the research on designing appropriate inhibitors aiding in chemotherapy and cancer related diseases

Analysis on Heavy Quarkonia Transitions with Pion Emission in Terms of the QCD Multipole Expansion and Determination of Mass Spectra of Hybrids

One of the most important tasks in high energy physics is search for the exotic states, such as glueball, hybrid and multi-quark states. The transitions $\psi(ns)\to \psi(ms)+\pi\pi$ and $\Upsilon(ns)\to \Upsilon(ms)+\pi\pi$ attract great attentions because they may reveal characteristics of hybrids. In this work, we analyze those transition modes in terms of the theoretical framework established by Yan and Kuang. It is interesting to notice that the intermediate states between the two gluon-emissions are hybrids, therefore by fitting the data, we are able to determine the mass spectra of hybrids. The ground hybrid states are predicted as 4.23 GeV (for charmonium) and 10.79 GeV (for bottonium) which do not correspond to any states measured in recent experiments, thus it may imply that very possibly, hybrids mix with regular quarkonia to constitute physical states. Comprehensive comparisons of the potentials for hybrids whose parameters are obtained in this scenario with the lattice results are presented.Comment: 16 pages, 2 figur

CHORUS Deliverable 4.3: Report from CHORUS workshops on national initiatives and metadata

Minutes of the following Workshops: • National Initiatives on Multimedia Content Description and Retrieval, Geneva, October 10th, 2007. • Metadata in Audio-Visual/Multimedia production and archiving, Munich, IRT, 21st – 22nd November 2007 Workshop in Geneva 10/10/2007 This highly successful workshop was organised in cooperation with the European Commission. The event brought together the technical, administrative and financial representatives of the various national initiatives, which have been established recently in some European countries to support research and technical development in the area of audio-visual content processing, indexing and searching for the next generation Internet using semantic technologies, and which may lead to an internet-based knowledge infrastructure. The objective of this workshop was to provide a platform for mutual information and exchange between these initiatives, the European Commission and the participants. Top speakers were present from each of the national initiatives. There was time for discussions with the audience and amongst the European National Initiatives. The challenges, communalities, difficulties, targeted/expected impact, success criteria, etc. were tackled. This workshop addressed how these national initiatives could work together and benefit from each other. Workshop in Munich 11/21-22/2007 Numerous EU and national research projects are working on the automatic or semi-automatic generation of descriptive and functional metadata derived from analysing audio-visual content. The owners of AV archives and production facilities are eagerly awaiting such methods which would help them to better exploit their assets.Hand in hand with the digitization of analogue archives and the archiving of digital AV material, metadatashould be generated on an as high semantic level as possible, preferably fully automatically. All users of metadata rely on a certain metadata model. All AV/multimedia search engines, developed or under current development, would have to respect some compatibility or compliance with the metadata models in use. The purpose of this workshop is to draw attention to the specific problem of metadata models in the context of (semi)-automatic multimedia search