Medical image denoising using convolutional denoising autoencoders

Image denoising is an important pre-processing step in medical image analysis. Different algorithms have been proposed in past three decades with varying denoising performances. More recently, having outperformed all conventional methods, deep learning based models have shown a great promise. These methods are however limited for requirement of large training sample size and high computational costs. In this paper we show that using small sample size, denoising autoencoders constructed using convolutional layers can be used for efficient denoising of medical images. Heterogeneous images can be combined to boost sample size for increased denoising performance. Simplest of networks can reconstruct images with corruption levels so high that noise and signal are not differentiable to human eye.Comment: To appear: 6 pages, paper to be published at the Fourth Workshop on Data Mining in Biomedical Informatics and Healthcare at ICDM, 201

Unsupervised patient representations from clinical notes with interpretable classification decisions

We have two main contributions in this work: 1. We explore the usage of a stacked denoising autoencoder, and a paragraph vector model to learn task-independent dense patient representations directly from clinical notes. We evaluate these representations by using them as features in multiple supervised setups, and compare their performance with those of sparse representations. 2. To understand and interpret the representations, we explore the best encoded features within the patient representations obtained from the autoencoder model. Further, we calculate the significance of the input features of the trained classifiers when we use these pretrained representations as input.Comment: Accepted poster at NIPS 2017 Workshop on Machine Learning for Health (https://ml4health.github.io/2017/

Reversible Recursive Instance-level Object Segmentation

In this work, we propose a novel Reversible Recursive Instance-level Object Segmentation (R2-IOS) framework to address the challenging instance-level object segmentation task. R2-IOS consists of a reversible proposal refinement sub-network that predicts bounding box offsets for refining the object proposal locations, and an instance-level segmentation sub-network that generates the foreground mask of the dominant object instance in each proposal. By being recursive, R2-IOS iteratively optimizes the two sub-networks during joint training, in which the refined object proposals and improved segmentation predictions are alternately fed into each other to progressively increase the network capabilities. By being reversible, the proposal refinement sub-network adaptively determines an optimal number of refinement iterations required for each proposal during both training and testing. Furthermore, to handle multiple overlapped instances within a proposal, an instance-aware denoising autoencoder is introduced into the segmentation sub-network to distinguish the dominant object from other distracting instances. Extensive experiments on the challenging PASCAL VOC 2012 benchmark well demonstrate the superiority of R2-IOS over other state-of-the-art methods. In particular, the $\text{AP}^r$ over $20$ classes at $0.5$ IoU achieves $66.7\%$, which significantly outperforms the results of $58.7\%$ by PFN~\cite{PFN} and $46.3\%$ by~\cite{liu2015multi}.Comment: 9 page