A Deep Dive into Understanding Tumor Foci Classification using Multiparametric MRI Based on Convolutional Neural Network

Deep learning models have had a great success in disease classifications using large data pools of skin cancer images or lung X-rays. However, data scarcity has been the roadblock of applying deep learning models directly on prostate multiparametric MRI (mpMRI). Although model interpretation has been heavily studied for natural images for the past few years, there has been a lack of interpretation of deep learning models trained on medical images. This work designs a customized workflow for the small and imbalanced data set of prostate mpMRI where features were extracted from a deep learning model and then analyzed by a traditional machine learning classifier. In addition, this work contributes to revealing how deep learning models interpret mpMRI for prostate cancer patients stratification

Towards Interpretable Deep Learning Models for Knowledge Tracing

As an important technique for modeling the knowledge states of learners, the traditional knowledge tracing (KT) models have been widely used to support intelligent tutoring systems and MOOC platforms. Driven by the fast advancements of deep learning techniques, deep neural network has been recently adopted to design new KT models for achieving better prediction performance. However, the lack of interpretability of these models has painfully impeded their practical applications, as their outputs and working mechanisms suffer from the intransparent decision process and complex inner structures. We thus propose to adopt the post-hoc method to tackle the interpretability issue for deep learning based knowledge tracing (DLKT) models. Specifically, we focus on applying the layer-wise relevance propagation (LRP) method to interpret RNN-based DLKT model by backpropagating the relevance from the model's output layer to its input layer. The experiment results show the feasibility using the LRP method for interpreting the DLKT model's predictions, and partially validate the computed relevance scores from both question level and concept level. We believe it can be a solid step towards fully interpreting the DLKT models and promote their practical applications in the education domain