485 research outputs found

    Thermal aging kinetic and effects on mechanical behavior of fully recycled composite based on polypropylene/polyethylene blend

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    The effect of thermal oxidation of a fully recycled carbon fibers reinforced stabilized polypropylene/polyethylene blend on the mechanical properties has been studied at 120, 130 and 140 °C. In a first step, several analyses by FTIR and UV spectrometry and differential scanning calorimetry were performed in order to detect and monitor the evolution of the antioxidants and oxidation products in the materials. This approach aims to well understand and identify the aging mechanisms that will be modeled in a second step in a kinetic model capable of predicting the evolution of carbonyl build-up while taking into account the presence of the different antioxidants. Modeling results showed a good correlation between the kinetic behavior and the obtained experimental data. Furthermore, the effect of thermal aging on the mechanical behaviors of the composite and the matrix were studied at the macroscopic scale at different strain rates. It has been shown that the thermal oxidation affects only the elongation at break. The numerical values of the oxidation products generated by the kinetic model allowed linking the evolution of the mechanical behavior under aging with the physicochemical state of the material

    MELISSE, a large multicentric observational study to determine risk factors of venous thromboembolism in patients with multiple myeloma treated with immunomodulatory drugs

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    International audienceImmunomodulatory drugs (IMiDs) are associated with an increased risk of venous thromboembolism (VTE) in multiple myeloma (MM) patients. We designed MELISSE, a multicentre prospective observational study, to evaluate VTE incidence and identify risk factors in IMiDs-treated MM. Our objective was to determine the real-life practice of VTE prophylaxis strategy. A total of 524 MM patients were included, and we planned to collect information at baseline, at four and at 12 months, on MM therapy, on VTE risk factors and management. VTE incidence was 7% (n=31), including 2.5% pulmonary embolism (PE) (n=11), similar at four or 12 months. VTE was observed at all risk assessment levels, although the increased risk assessment level correlated to a lower rate of VTE, maybe due to the implemented thromboprophylaxis strategy. VTE occurred in 7% on aspirin vs 3% on low-molecular-weight heparin (LMWH) prophylaxis, and none on vitamin K antagonists (VKA). New risk factors for VTE in IMiDs-treated MM were identified. In conclusion, VTE prophylaxis is compulsory in IMiDs-treated MM, based on individualised VTE risk assessment. Anticoagulation prophylaxis with LMWH should clearly be prioritised in MM patients with high VTE risk, along with VKA. Further prospective studies will identify most relevant VTE risk factors in IMiDs-treated MM to select accurately which MM patients should receive LMWH prophylaxis and for which duration to optimise VTE risk reduction

    Retos en la medición del desempeño económico y social

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    Es común que los indicadores económicos y sociales sean criticados, calificán-dolos de incompletos y arbitrarios. Puede que, en verdad, lo sean. Pero aún reco-nociendo sus limitaciones, suministran información que ha ayudado a identificar y solucionar problemas relevantes del pasado. Hace 200 años, la expectativa de vida al nacer en el mundo no superaba los 40 años, ni siquiera en Holanda e Ingla-terra, los países más ricos de la época. Desde entonces, a pesar de enfermedades, hambrunas y guerras, la humanidad ha elevado su expectativa de vida a razón de tres meses anuales: hoy en muchos países la expectativa de vida al nacer se acerca a los 80 años. Ningún país del mundo tiene una esperanza de vida inferior a la de hace 200 años. Incluso en la República Democrática del Congo, el país más pobre del planeta, la gente vive más de 45 años (The Economist, 2011, p. 80-81)incluye referencias bibliográficas (página 247)

    Beyond the Short Term A Study of Past Productivity’s Trends and an Evaluation of Future Ones

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    This is the second report to be issued by a group of international economists brought together under the auspices of LUISS. LIGEP stands for LUISS International Group on Economic Policy. Its mandate was to consider problems of economic policy in the aftermath of the Global Crisis in the World, Europe and Italy
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