Adjusting medication at the end of life:towards optimalisation of healthcare in the final fase of life

Patients with a limited life expectancy use many medications. Especially medications with a focus on the prevention and treatment of illnesses may be inappropriate in this last phase of life. We present the cases of three patients in which we highlight that such medication reconsideration 1) is quite often done shortly before death, 2) is not without potential disadvantages, and 3) should be accompanied with a patient centered and positive communication style. We argue that the use of medications should be reconsidered in a timely phase, ideally as part of advance care planning.</p