5,705 research outputs found
Supersymmetric Brane World Scenarios from Off-Shell Supergravity
Using N=2 off-shell supergravity in five dimensions, we supersymmetrize the
brane world scenario of Randall and Sundrum. We extend their construction to
include supersymmetric matter at the fixpoints.Comment: 15 pages, no figures, late
Reduced brain activation during inhibitory control in children with COMT Val/Val genotype
IntroductionBehavioral undercontrol is a wellâestablished risk factor for substance use disorder, identifiable at an early age well before the onset of substance use. However, the biological mechanistic structure underlying the behavioral undercontrol/substance use relationship is not well understood. The enzyme catechol Oâmethyltransferase (COMT) catabolizes dopamine and norepinephrine in the prefrontal cortex and striatum, brain regions involved in behavioral control. The goal of this work was to investigate the association between genetic variation in COMT functioning and frontoâstriatal brain functioning during successful inhibitory control, a critical aspect of behavioral control.MethodsParticipants were 65 (22 female) 7â12Â year olds who were genotyped for the functional COMT Val158Met (rs4680) singleânucleotide polymorphism and underwent functional magnetic resonance imaging while performing a go/noâgo task. The majority of the sample (80%) had at least one parent with a history of alcohol use disorder and were thus at heightened risk for substance use disorders.ResultsThere was a significant main effect of genotype on brain activation in left and right putamen during successful versus failed inhibition and in right inferior frontal gyrus/insula during successful inhibition versus baseline. Followâup tests revealed that Met homozygotes had greater activation in each region relative to Val homozygotes.ConclusionsThese results are relevant for understanding how specific genes influence brain functioning related to underlying risk factors for substance use disorders and other disinhibitory psychopathologies.The goal of this work was to investigate the association between genetic variation in COMT functioning and frontoâstriatal brain functioning during inhibitory control, a critical aspect of behavioral control. Participants were 65 (22 female) 7â12Â year olds who were genotyped for the functional COMT Val158Met (rs4680) singleânucleotide polymorphism and underwent functional magnetic resonance imaging while performing a go/noâgo task. There was a significant main effect of genotype on brain activation in left and right putamen during successful versus failed inhibition and in right inferior frontal gyrus/insula during successful inhibition versus baseline; followâup tests revealed that Met homozygotes had greater activation in each region relative to Val homozygotes.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/135697/1/brb3577_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/135697/2/brb3577.pd
A Bayesian Approach to Locating the Red Giant Branch Tip Magnitude (Part I)
We present a new approach for identifying the Tip of the Red Giant Branch
(TRGB) which, as we show, works robustly even on sparsely populated targets.
Moreover, the approach is highly adaptable to the available data for the
stellar population under study, with prior information readily incorporable
into the algorithm. The uncertainty in the derived distances is also made
tangible and easily calculable from posterior probability distributions. We
provide an outline of the development of the algorithm and present the results
of tests designed to characterize its capabilities and limitations. We then
apply the new algorithm to three M31 satellites: Andromeda I, Andromeda II and
the fainter Andromeda XXIII, using data from the Pan-Andromeda Archaeological
Survey (PAndAS), and derive their distances as
kpc, kpc and
kpc respectively, where the errors appearing in parentheses are the components
intrinsic to the method, while the larger values give the errors after
accounting for additional sources of error. These results agree well with the
best distance determinations in the literature and provide the smallest
uncertainties to date. This paper is an introduction to the workings and
capabilities of our new approach in its basic form, while a follow-up paper
shall make full use of the method's ability to incorporate priors and use the
resulting algorithm to systematically obtain distances to all of M31's
satellites identifiable in the PAndAS survey area.Comment: 11 pages, 18 figure
A Keck/DEIMOS spectroscopic survey of faint Galactic satellites: searching for the least massive dwarf galaxies
[abridged] We present the results of a spectroscopic survey of the recently
discovered faint Milky Way satellites Boo, UMaI, UMaII and Wil1. Using the
DEIMOS spectrograph on Keck, we have obtained samples that contain from 15 to
85 probable members of these satellites for which we derive radial velocities
precise to a few km/s down to i~21-22. About half of these stars are observed
with a high enough S/N to estimate their metallicity to within \pm0.2 dex. From
this dataset, we show that UMaII is the only object that does not show a clear
radial velocity peak. However, the measured systemic radial velocity
(v_r=115\pm5 km/s) is in good agreement with recent simulations in which this
object is the progenitor of the recently discovered Orphan Stream. The three
other satellites show velocity dispersions that make them highly dark-matter
dominated systems. In particular the Willman 1 object is not a globular cluster
given its metallicity scatter over -2.0<[Fe/H]<-1.0 and is therefore almost
certainly a dwarf galaxy or dwarf galaxy remnant. We measure a radial velocity
dispersion of only 4.3_{-1.3}^{+2.3} km/s around a systemic velocity of
-12.3\pm2.3 km/s which implies a mass-to-light ratio of ~700 and a total mass
of ~5x10^5 Msun for this satellite, making it the least massive satellite
galaxy known to date. Such a low mass could mean that the 10^7 Msun limit that
had until now never been crossed for Milky Way and Andromeda satellite galaxies
may only be an observational limit and that fainter, less massive systems exist
within the Local Group. However, more modeling and an extended search for
potential extra-tidal stars are required to rule out the possibility that these
systems have not been significantly heated by tidal interaction.Comment: 24 pages, 11 figures, MNRAS accepte
Stability of the Higgs mass in theories with extra dimensions
We analyze the ultraviolet stability of the Higgs mass in recently proposed
Kaluza-Klein models compactified on S_1/Z_2 or S_1/(Z_2\times Z_2'), both at
the field theory and string theory level. Fayet-Iliopoulos terms of U(1)
hypercharge are shown to be of vital importance for this discussion. Models
with a single Higgs doublet seem to be generically affected by quadratic
divergences.Comment: Contribution to the Proceedings of Durham IPPP meeting May 2001.(12
pages, LaTeX
Adaptive thermal compensation of test masses in advanced LIGO
As the first generation of laser interferometric gravitational wave detectors
near operation, research and development has begun on increasing the
instrument's sensitivity while utilizing the existing infrastructure. In the
Laser Interferometer Gravitational Wave Observatory (LIGO), significant
improvements are being planned for installation in ~2007, increasing strain
sensitivity through improved suspensions and test mass substrates, active
seismic isolation, and higher input laser power. Even with the highest quality
optics available today, however, finite absorption of laser power within
transmissive optics, coupled with the tremendous amount of optical power
circulating in various parts of the interferometer, result in critical
wavefront deformations which would cripple the performance of the instrument.
Discussed is a method of active wavefront correction via direct thermal
actuation on optical elements of the interferometer. A simple nichrome heating
element suspended off the face of an affected optic will, through radiative
heating, remove the gross axisymmetric part of the original thermal distortion.
A scanning heating laser will then be used to remove any remaining
non-axisymmetric wavefront distortion, generated by inhomogeneities in the
substrate's absorption, thermal conductivity, etc. A proof-of-principle
experiment has been constructed at MIT, selected data of which are presented.Comment: 11 pages, 7 figures, submitted to Classical and Quantum Gravit
Histomorphometric Analysis of the Rat Proximal Tibial Metaphysis by âLinear Scanningâ
Twenty-four female Sprague-Dawley rats (10 weeks old, 200g BW) were either sham-operated (n = 6) or ovariectomized (ovx). Ovx rats were divided into 3 groups (n = 6 each) : ovx; ovx + 1,25(OH) 2D3; ovx + l,25(OH)2D3 + 1,24,25(OH)3D3. The vitamin D metabolites were fed orally starting the day after surgery. After 7 weeks all rats were sacrificed and the proximal tibiae were processed undecalcified for quantitative histomorphometry. Conventional histomorphometric analysis of the distal zone (\u3e 1 mm from the growth cartilage) of the tibial metaphysis revealed a dramatic loss of cancellous bone mass in ovx rats. Both l,25(OH)2D3 and the combination of l,25(OH)2D3 with l,24,25(OH)3D3 prevented the bone loss in the distal zone in ovx animals. Measurements in the proximal zone (\u3c 1 mm from the growth cartilage) of the tibial metaphysis were performed with a newly developed technique that utilizes the advantages of automatic image analysis, and that we propose to name linear scanning . This method revealed a significantly decreased hard tissue mass at about 100 ÎŒm and within 800 to 950 ÎŒm distance from the growth plate in ovx rats. However, ovx rats reached normal amounts of hard tissue within 250 to 450 ÎŒm from the growth plate. The results obtained by linear scanning suggest that the obvious loss of cancellous bone mass in the distal zone of the tibial metaphysis in growing ovx rats is not a consequence of structural changes in the proximal zone
Universal contributions to scalar masses from five dimensional supergravity
We compute the effective Kahler potential for matter fields in warped
compactifications, starting from five dimensional gauged supergravity, as a
function of the matter fields localization. We show that truncation to zero
modes is inconsistent and the tree-level exchange of the massive gravitational
multiplet is needed for consistency of the four-dimensional theory. In addition
to the standard Kahler coming from dimensional reduction, we find the quartic
correction coming from integrating out the gravity multiplet. We apply our
result to the computation of scalar masses, by assuming that the SUSY breaking
field is a bulk hypermultiplet. In the limit of extreme opposite localization
of the matter and the spurion fields, we find zero scalar masses, consistent
with sequestering arguments. Surprisingly enough, for all the other cases the
scalar masses are tachyonic. This suggests the holographic interpretation that
a CFT sector always generates operators contributing in a tachyonic way to
scalar masses. Viability of warped su- persymmetric compactifications
necessarily asks then for additional contributions. We discuss the case of
additional bulk vector multiplets with mixed boundary conditions, which is a
partic- ularly simple and attractive way to generate large positive scalar
masses. We show that in this case successful fermion mass matrices implies
highly degenerate scalar masses for the first two generations of squarks and
sleptons.Comment: 23 pages. v2: References added, new section on effect of additional
bulk vector multiplets and phenomenolog
Ultracompact, low-loss directional couplers on InP based on self-imaging by multimode interference
We report extremely compact (494-”m-long 3 dB splitters, including input/output bends), polarization-insensitive, zero-gap directional couplers on InP with a highly multimode interference region that are based on the self-imaging effect. We measured cross-state extinctions better than 28 dB and on-chip insertion losses of 0.5 dB/coupler plus 1 dB/cm guide propagation loss at 1523 nm wavelength
- âŠ