Mathematical model of heat exchange processes for heat ptotective cooling suit of a rescuer

Fires are followed by the range of factors hazardous for human health; a radiant thermal stream accompanied by the high temperature of the environment is one of these factors. For protection of firemen special protective clothing from heat impact and the insulation type clothing are used. The paper demonstrates that the concept of action of such clothing is based on the passive heat protection owing to the use of materials with low conducting capacity or high specific heat. The time of effective protection of a suit is not considerable which reduces the duration of work under the unfavorable climatic conditions drastically, increases the work labor input, leads to the hyperthermia. One of the ways focused on the improvement of the heat protective clothing is a design of suits with cooling, which is stated in the paper. The paper shows that the developed heat protective suits on the basis of water-ice cooling elements are not widely used due to considerable costs. A more reasonable idea refers to the design of heat protective suits with cooling by using running water as the most available coolant circulating along polyvinylchloride pipes arranged between the layers of a suit. The objective stated in the paper is to derive the patterns of non-stationary heat exchange processes in the system «heat flow of the fire source – heat protective suit – rescuer’s body» with cooling the rescuer’s organism by running water circulating along polyvinylchloride pipes in the inner lining space as well as a development of a method to determine time of effective protection of the heat protective suit which was realized by solving the equation of non-stationary heat conductivity by the finite elements method. A mathematical model differs in the way of taking into consideration the external radiant thermal stream from a fire, internal thermal stream of a rescuer’s body, heat insulation properties of the suit materials, their geometrical parameters, temperature of coolant. The paper stated that the time of effective protection of a protective suit with water cooling is well above in comparison with the suits of a similar purposes for firemen and rescuers of the Ministry of emergency situations

Adhesive organelles of Gram-negative pathogens assembled with the classical chaperone/usher machinery: structure and function from a clinical standpoint

This review summarizes current knowledge on the structure, function, assembly and biomedical applications of the superfamily of adhesive fimbrial organelles exposed on the surface of Gram-negative pathogens with the classical chaperone/usher machinery. High-resolution three-dimensional (3D) structure studies of the minifibers assembling with the FGL (having a long F1-G1 loop) and FGS (having a short F1-G1 loop) chaperones show that they exploit the same principle of donor-strand complementation for polymerization of subunits. The 3D structure of adhesive subunits bound to host-cell receptors and the final architecture of adhesive fimbrial organelles reveal two functional families of the organelles, respectively, possessing polyadhesive and monoadhesive binding. The FGL and FGS chaperone-assembled polyadhesins are encoded exclusively by the gene clusters of the gamma 3- and kappa-monophyletic groups, respectively, while gene clusters belonging to the gamma 1-, gamma 2-, gamma 4-, and pi-fimbrial clades exclusively encode FGS chaperone-assembled monoadhesins. Novel approaches are suggested for a rational design of antimicrobials inhibiting the organelle assembly or inhibiting their binding to host-cell receptors. Vaccines are currently under development based on the recombinant subunits of adhesins

Once again on the equivalence theorem

We present the proof of the equivalence theorem in quantum field theory which is based on a formulation of this problem in the field-antifield formalism. As an example, we consider a model in which a different choices of natural finite counterterms is possible, leading to physically non-equivalent quantum theories while the equivalent theorem remains valid.Comment: 12 pages, LATEX, report number was correcte

Initial Conditions for Semiclassical Field Theory

Semiclassical approximation based on extracting a c-number classical component from quantum field is widely used in the quantum field theory. Semiclassical states are considered then as Gaussian wave packets in the functional Schrodinger representation and as Gaussian vectors in the Fock representation. We consider the problem of divergences and renormalization in the semiclassical field theory in the Hamiltonian formulation. Although divergences in quantum field theory are usually associated with loop Feynman graphs, divergences in the Hamiltonian approach may arise even at the tree level. For example, formally calculated probability of pair creation in the leading order of the semiclassical expansion may be divergent. This observation was interpretted as an argumentation for considering non-unitary evolution transformations, as well as non-equivalent representations of canonical commutation relations at different time moments. However, we show that this difficulty can be overcomed without the assumption about non-unitary evolution. We consider first the Schrodinger equation for the regularized field theory with ultraviolet and infrared cutoffs. We study the problem of making a limit to the local theory. To consider such a limit, one should impose not only the requirement on the counterterms entering to the quantum Hamiltonian but also the requirement on the initial state in the theory with cutoffs. We find such a requirement in the leading order of the semiclassical expansion and show that it is invariant under time evolution. This requirement is also presented as a condition on the quadratic form entering to the Gaussian state.Comment: 20 pages, Plain TeX, one postscript figur

Structural Insight into Archaic and Alternative Chaperone-Usher Pathways Reveals a Novel Mechanism of Pilus Biogenesis

AVZ is supported by the Finnish Academy (grants 140959 and 273075; http://sciencenordic.com/partner/academy-finland) and Sigrid Juselius Foundation (grant 2014; www.sigridjuselius.fi/foundation). SMis supported by the Wellcome Trust (Senior Investigator Award 100280, Programme grant 079819; http://www.wellcome.ac.uk) The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

Breather solution of non-linear Klein-Gordon equation

A technique for obtaining an approximate breather solution of the Klein-Gordon equation is presented. A breather solution of the equation describing the propagation of nonlinear waves in a graphene-based superlattice is investigated.Comment: 16 pages, 5 figure