241 research outputs found

    Radical prostatectomy with and without adjuvant radiotherapy for pT3N0 prostate cancer

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    THE EFFECT OF PROTEIN SOURCE ON PARAMETERS OF RUMEN CONTENT AND DIGESTIBILITY OF NUTRIENTS IN FATTENING LAMBS

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    Abstract D. RuZiC-MusliCH, M. P. PetRoviCH, M. M. PetRoviCH, P. PeRisiCH, Z. BijeliCH, v. PanteliCH and v. CaRo-PetRoviCH, 2013. the effect of protein source on parameters of rumen content and digestibility of nutrients in fattening lambs. Bulg. J Agric. Sci., In this paper, results of the study of the effect of different protein sources in concentrate mixtures on fluid rumen content and digestibility of nutrients in fattening lambs are presented. Physiological study included 18 male lambs of Mis population, average body mass of approx, 35.0 kg, divided into three groups. Lambs were fed isoprotein concentrate mixtures (14% CP) which differed about protein source: sunflower meal (I), soybean meal (II) and fishmeal (III), resulting in different ratio of protein non-degradable in rumen: 43% (I), 51% (II) and 58% (iii), respectively. Content of ammonia nitrogen (nH 3 -N) in rumen fluid of fattening lambs in said treatments was 42.46: 33.86: 31.35 mg/100 ml. pH rumen value in treatments i: ii: iii were 6.56: 6.35: 6.15. Trial results show that the level of protein intake was not under significant influence of studied treatment, considering that digestibility coefficients were 52.58%: 51.30%: 55.12%. With the increase of the share of non-degradable protein in concentrate mixtures, the tendency of fat digestibility increase was observed: 76.13: 77.98: 87.17%, also of decrease of cellulose intake: 67.40: 45.87: 22.39% and nFe: 83.87: 76.05: 82.96%

    Оценка содержания урана в питьевой воде: исследование в Павлодарской области, Казахстан

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    This paper presents research results on uranium in drinking water in the territory of the Pavlodar region. Research data shows that uranium content in water is significantly higher than its maximum permissible concentration of 0.015 mg/dm3 as stated in the acts, which Russia and the USA has approved by the PEL of 32 [mu]g/l. Two out of five settlements where uranium concentration in water is at its peak suffer from anthropogenic impact. The results show that water in the northeastern part of the investigated area contains high uranium level due to geological and metallogenic peculiarities of the region

    Complementary analysis of modal content and properties in a 19-cell hollow core photonic band gap fiber using Time-of-Flight and S2 techniques

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    We study the rich multimode content of an ultra-low loss hollow core photonic bandgap fiber using two complementary techniques which allow us to investigate both short and long propagation distances. Several distinct vector modes are clearly identified, with evidence of low intermodal coupling and distributed scattering

    Оценка содержания урана в питьевой воде: исследование в Павлодарской области, Казахстан

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    This paper presents research results on uranium in drinking water in the territory of the Pavlodar region. Research data shows that uranium content in water is significantly higher than its maximum permissible concentration of 0.015 mg/dm3 as stated in the acts, which Russia and the USA has approved by the PEL of 32 [mu]g/l. Two out of five settlements where uranium concentration in water is at its peak suffer from anthropogenic impact. The results show that water in the northeastern part of the investigated area contains high uranium level due to geological and metallogenic peculiarities of the region

    Antiresonant hollow core fiber with an octave spanning bandwidth for short haul data communications

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    We report an effectively single mode tubular antiresonant hollow core fiber with minimum loss of ~25 dB/km at ~1200 nm, and an extremely wide low loss transmission window (lower than 30 dB/km loss from 1000 nm to 1400 nm and 6 dB bandwidth exceeding 1000 nm). Despite the relatively large mode field diameter of 32 µm, the fiber can be interfaced to SMF28 to produce fully connectorized samples. Exploiting an excellent modal purity arising from large modal differential loss and low intermodal coupling, we demonstrate penalty-free 10G on-off keying data transmission through 100m of fiber, at wavelengths of 1065, 1565 and 1963nm

    MASEP gamma knife radiosurgery for secretory pituitary adenomas: experience in 347 consecutive cases

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    <p>Abstract</p> <p>Background</p> <p>Secretory pituitary adenomas are very common brain tumors. Historically, the treatment armamentarium for secretory pituitary adenomas included neurosurgery, medical management, and fractionated radiotherapy. In recent years, MASEP gamma knife radiosurgery (MASEP GKRS) has emerged as an important treatment modality in the management of secretory pituitary adenomas. The goal of this research is to define accurately the efficacy, safety, complications, and role of MASEP GKRS for treatment of secretory pituitary adenomas.</p> <p>Methods</p> <p>Between 1997 and 2007 a total of 347 patients with secretory pituitary adenomas treated with MASEP GKRS and with at least 60 months of follow-up data were identified. In 47 of these patients some form of prior treatment such as transsphenoidal resection, or craniotomy and resection had been conducted. The others were deemed ineligible for microsurgery because of body health or private choice, and MASEP GKRS served as the primary treatment modality. Endocrinological, ophthalmological, and neuroradiological responses were evaluated.</p> <p>Results</p> <p>MASEP GKRS was tolerated well in these patients under the follow-up period ranged from 60 to 90 months; acute radioreaction was rare and 17 patients had transient headaches with no clinical significance. Late radioreaction was noted in 1 patient and consisted of consistent headache. Of the 68 patients with adrenocorticotropic hormone-secreting(ACTH) adenomas, 89.7% showed tumor volume decrease or remain unchanged and 27.9% experienced normalization of hormone level. Of the 176 patients with prolactinomas, 23.3% had normalization of hormone level and 90.3% showed tumor volume decrease or remain unchanged. Of the 103 patients with growth hormone-secreting(GH) adenomas, 95.1% experienced tumor volume decrease or remain unchanged and 36.9% showed normalization of hormone level.</p> <p>Conclusion</p> <p>MASEP GKRS is safe and effective in treating secretory pituitary adenomas. None of the patients in our study experienced injury to the optic apparatus or had other neuropathies related with gamma knife. MASEP GKRS may serve as a primary treatment method in some or as a salvage treatment in the others. However, treatment must be tailored to meet the patient's symptoms, tumor location, tumor morphometry, and overall health. Longer follow-up is required for a more complete assessment of late radioreaction and treatment efficacy.</p

    Do Hadronic Charge Exchange Reactions Measure Electroweak L = 1 Strength?

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    An eikonal model has been used to assess the relationship between calculated strengths for first forbidden beta decay and calculated cross sections for (p,n) charge exchange reactions. It is found that these are proportional for strong transitions, suggesting that hadronic charge exchange reactions may be useful in determining the spin-dipole matrix elements for astrophysically interesting leptonic transitions.Comment: 14 pages, 5 figures, Submitted to Physical Review

    Chemotherapy-Induced Neuronal Maturation in Sinonasal Teratocarcinosarcoma—a Unique Observation

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    Sinonasal teratocarcinosarcoma (SNTCS) is a rare and highly malignant tumour with combined features of a teratoma and carcinosarcoma. We report the first case of a SNTCS in 23 year old male treated with neo-adjuvant chemotherapy followed by cranio-facial resection. The resection specimen displayed cellular maturation in the neuroectodermal component. The patient presented with a short history of nasal obstruction, epistaxis and headache. On imaging, a bone destroying lesion of left paranasal sinuses and nasal cavity was identified. The diagnosis of SNTCS could be offered only on the third biopsy which showed heterogeneous admixture of primitive neuroectodermal, epithelial and mesenchymal elements. An adequate sampling with high index of suspicion is needed to catch hold this rare tumor. Tumor was excised after 4 cycles of neo-adjuvant chemotherapy. On microscopic examination, it showed similar epithelial and mesenchymal components as the pretreatment biopsies. However, the primitive neuroectodermal component displayed extensive neuronal maturation. The undifferentiated neuroectodermal cells were completely absent in the post chemotherapy specimen. This case throws light on the morphologic evidence of chemotherapy induced maturation in the neuroectodermal component within SNTCS, an event hitherto not reported in the literature in case of SNTCS

    Radiosurgery for pituitary adenomas: evaluation of its efficacy and safety

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    <p>Abstract</p> <p>Object</p> <p>To assess the effects of radiosurgery (RS) on the radiological and hormonal control and its toxicity in the treatment of pituitary adenomas.</p> <p>Methods</p> <p>Retrospective analysis of 42 patients out of the first 48 consecutive patients with pituitary adenomas treated with RS between 1999 and 2008 with a 6 months minimum follow-up. RS was delivered with Gamma Knife as a primary or adjuvant treatment. There were 14 patients with non-secretory adenomas and, among functioning adenomas, 9 were prolactinomas, 9 were adrenocorticotropic hormone-secreting and 10 were growth hormone-secreting tumors. Hormonal control was defined as hormonal response (decline of more than 50% from the pre-RS levels) and hormonal normalization. Radiological control was defined as stasis or shrinkage of the tumor. Hypopituitarism and visual deficit were the morbidity outcomes. Hypopituitarism was defined as the initiation of any hormone replacement therapy and visual deficit as loss of visual acuity or visual field after RS.</p> <p>Results</p> <p>The median follow-up was 42 months (6-109 months). The median dose was 12,5 Gy (9 - 15 Gy) and 20 Gy (12 - 28 Gy) for non-secretory and secretory adenomas, respectively. Tumor growth was controlled in 98% (41 in 42) of the cases and tumor shrinkage ocurred in 10% (4 in 42) of the cases. The 3-year actuarial rate of hormonal control and normalization were 62,4% and 37,6%, respectively, and the 5-year actuarial rate were 81,2% and 55,4%, respectively. The median latency period for hormonal control and normalization was, respectively, 15 and 18 months. On univariate analysis, there were no relationships between median dose or tumoral volume and hormonal control or normalization. There were no patients with visual deficit and 1 patient had hypopituitarism after RS.</p> <p>Conclusions</p> <p>RS is an effective and safe therapeutic option in the management of selected patients with pituitary adenomas. The short latency of the radiation response, the highly acceptable radiological and hormonal control and absence of complications at this early follow-up are consistent with literature.</p
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