CHARACTERISTICS OF THROWING MOTION OF OVERPOWERING FASTBALL COLLEGE PITCHERS

The purpose of this study was to compare the motion pattern of overpowering fastball pitchers. The throwing motion of eighteen male college pitchers were analysed using a motion capture system. This study focused on the movements of the pivot leg and the trunk during the preparatory phase. The overpowering fastball pitchers in the present study largely abducted the hip of the pivot leg and leaned the trunk toward the pivot leg during the preparatory phase. That these motions were seen during the preparatory phase would reveal that a key motion to get fast ball speed exist in the preparatory phase

Triplet Analysis That Identifies Unpaired Regions of Functional RNAs

We developed a novel method for analyzing RNA sequences, deemed triplet analysis, and applied the method in an in vitro RNA selection experiment in which HIV-1 Tat was the target. Aptamers are nucleic acids that bind a desired target (bait), and to date, many aptamers have been identified by in vitro selection from enough concentrated libraries in which many RNAs had an obvious consensus primary sequence after sufficient cycles of the selection. Therefore, the higher-order structural features of the aptamers that are indispensable for interaction with the bait must be determined by additional investigation of the aptamers. In contrast, our triplet analysis enabled us to extract important information on functional primary and secondary structure from minimally concentrated RNA libraries. As a result, by using our method, an important unpaired region that is similar to the bulge of TAR was readily predicted from a partially concentrated library in which no consensus sequence was revealed by a conventional sequence analysis. Moreover, our analysis method may be used to assess a variety of structural motifs with desired function

Atiyah-Patodi-Singer index on a lattice

We propose a non-perturbative formulation of the Atiyah-Patodi-Singer(APS) index in lattice gauge theory, in which the index is given by the $\eta$ invariant of the domain-wall Dirac operator. Our definition of the index is always an integer with a finite lattice spacing. To verify this proposal, using the eigenmode set of the free domain-wall fermion, we perturbatively show in the continuum limit that the curvature term in the APS theorem appears as the contribution from the massive bulk extended modes, while the boundary $\eta$ invariant comes entirely from the massless edge-localized modes.Comment: 14 pages, appendices added, details of key equations added, typos corrected, to appear in PTE

Petrogenesis of Yamato-75032 type diogenites

The Tenth Symposium on Polar Science/Special session: [OA] Antarctic meteorites, Thur. 5 Dec. / 3F Multipurpose conference room, National Institute of Polar Researc

Effect of αB-Crystallin on Protein Aggregation in Drosophila

Disorganisation and aggregation of proteins containing expanded polyglutamine (polyQ) repeats, or ectopic expression of α-synuclein, underlie neurodegenerative diseases including Alzheimer's, Parkinson, Huntington, Creutzfeldt diseases. Small heat-shock proteins, such as αB-crystallin, act as chaperones to prevent protein aggregation and play a key role in the prevention of such protein disorganisation diseases. In this study, we have explored the potential for chaperone activity of αB-crystallin to suppress the formation of protein aggregates. We tested the ability of αB-crystallin to suppress the aggregation of a polyQ protein and α-synuclein in Drosophila. We found that αB-crystallin suppresses both the compound eye degeneration induced by polyQ and the α-synuclein-induced rough eye phenotype. Furthermore, by using histochemical staining we have determined that αB-crystallin inhibits the aggregation of polyQ in vivo. These data provide a clue for the development of therapeutics for neurodegenerative diseases

Flow of a circulating tumor cell and red blood cells in microvessels

Quantifying the behavior of circulating tumor cells (CTCs) in the blood stream is of fundamental importance for understanding metastasis. Here, we investigate the flow mode and velocity of CTCs interacting with red blood cells (RBCs) in various sized microvessels. The flow of leukocytes in microvessels has been described previously; a leukocyte forms a train with RBCs in small microvessels and exhibits margination in large microvessels. Important differences in the physical properties of leukocytes and CTCs result from size. The dimensions of leukocytes are similar to those of RBCs, but CTCs are significantly larger. We investigate numerically the size effects on the flow mode and the cell velocity, and we identify similarities and differences between leukocytes and CTCs. We find that a transition from train formation to margination occurs when (R-a)/tR≈1, where R is the vessel radius, a is the cell radius, and tR is the thickness of RBCs, but that the motion of RBCs differs from the case of leukocytes. Our results also show that the velocities of CTCs and leukocytes are larger than the average blood velocity, but only CTCs move faster than RBCs for microvessels of R/a≈1.5-2.0. These findings are expected to be useful not only for understanding metastasis, but also for developing microfluidic devices.Takeishi N., Imai Y., Yamaguchi T., et al. Flow of a circulating tumor cell and red blood cells in microvessels. Physical Review E - Statistical, Nonlinear, and Soft Matter Physics, 92, 6, 063011. https://doi.org/10.1103/PhysRevE.92.063011

Will Preoperative Atrophy and Fatty Degeneration of the Shoulder Muscles Improve after Rotator Cuff Repair in Patients with Massive Rotator Cuff Tears?

Recently, retear rate after repair for massive cuff tear have been improved through devised suture techniques. However, reported retear rate is relevant to preoperative atrophy and fatty degeneration. The purpose of this study was to investigate whether preoperative atrophy and fatty degeneration of rotator cuff muscles improve by successful repair. Twenty-four patients with massive rotator cuff tear were evaluated on the recovery of atrophy and fatty degeneration of supraspinatus and infraspinatus muscle after surgery. Atrophy was classified by the occupation ratio and fatty degeneration by modified Goutallier's classification. Both were assessed on magnetic resonance imaging (MRI) before and after the operation. When the cuff was well repaired, improvement of the atrophy and fatty degeneration were observed in a half and a one-fourth of the cases, respectively. In retear cases, however, atrophy and fatty degeneration became worse. Improvement of atrophy and fatty degeneration of the rotator cuff muscles may be expected in the cases with successful achievement of rotator cuff repair for large and massive tear

Pose Estimation for Human Wearing Loose-Fitting Clothes: Obtaining Ground Truth Posture Using HFR Camera and Blinking LEDs

Human pose estimation, particularly in athletes, can help improve their performance. However, this estimation is difficult using existing methods, such as human annotation, if the subjects wear loose-fitting clothes such as ski/snowboard wears. This study developed a method for obtaining the ground truth data on two-dimensional (2D) poses of a human wearing loose-fitting clothes. This method uses fast-flushing light-emitting diodes (LEDs). The subjects were required to wear loose-fitting clothes and place the LED on the target joints. The LEDs were observed directly using a camera by selecting thin filmy loose-fitting clothes. The proposed method captures the scene at 240 fps by using a high-frame-rate camera and renders two 30 fps image sequences by extracting LED-on and -off frames. The temporal differences between the two video sequences can be ignored, considering the speed of human motion. The LED-on video was used to manually annotate the joints and thus obtain the ground truth data. Additionally, the LED-off video, equivalent to a standard video at 30 fps, confirmed the accuracy of existing machine learning-based methods and manual annotations. Experiments demonstrated that the proposed method can obtain ground truth data for standard RGB videos. Further, it was revealed that neither manual annotation nor the state-of-the-art pose estimator obtains the correct position of target joints.Comment: Extended abstract of WACV2023 workshop on Computer Vision 4 Winter Sport