On the influence of the Sun on the rapid variability of compact extragalactic sources

Starting from December 2004, a program for the monitoring of intraday variable sources at a frequency of 5 GHz was performed at the Urumqi Observatory. The analysis of the variability characteristics of the flat-spectrum radio source AO 0235+164 revealed the existence of an annual cycle in the variability amplitude. This appears to correlate with the solar elongation of the source. A thorough analysis of the results of the MASIV IDV survey --- which provides the variability characteristics of a large sample of compact radio sources --- confirms that there is a small but detectable component of the observed fractional modulation which increases with decreasing solar elongation. We discuss the hypothesis that the phenomenon is related to interplanetary scintillation.Comment: 10 pages, 12 figures and 2 tables. Accepted for publication in Astronomy and Astrophysic

The IDV source J1128+5925, a new candidate for annual modulation?

Short time-scale radio variations of compact extragalactic radio sources, known as IntraDay Variability, can be explained in at least some sources by a source-extrinsic effect, in which the variations are interpreted as scintillation of radio waves caused by the turbulent ISM of the Milky Way. One of the most convincing observational arguments in favour of propagation-induced variability is the so called annual modulation of the characteristic variability time-scale, which is due to the orbital motion of the Earth. Data for the recently discovered and highly variable IDV source J1128+5925 are presented. We study the frequency and time dependence of the IDV in this compact quasar. We measure the characteristic variability time-scale of the IDV throughout the year, and analyze whether the observed changes in the variability time-scale are consistent with annual modulation. We monitored the flux density variability of J1128+5925 with dense time sampling between 2.7 and 10.45GHz with the 100m Effelsberg radio telescope of the MPIfR and with the 25m Urumqi radio telescope. From ten observing sessions, we determine the variability characteristics and time-scales. The observed pronounced changes of the variability time-scale of J1128+5925 are modelled with an anisotropic annual modulation model. The observed frequency dependence of the variation is in good agreement with the prediction from interstellar scintillation. Adopting a simple model for the annual modulation model and using also the frequency dependence of the IDV, we derive a lower limit to the distance of the scattering screen and an upper limit to the scintillating source size. The latter is found to be consistent with the measured core size from VLBI.Comment: 15 pages, 9 figures Accepted for publication in Astronomy and Astrophysic

Intra-day variability observations of S5 0716+714 over 4.5 years at 4.8 GHz

We aim to search for evidence of annual modulation in the time scales of the BL Lac object S5 0716+714. The intra-day variability (IDV) observations were carried out monthly from 2005 to 2009, with the Urumqi 25m radio telescope at 4.8 GHz. The source has shown prominent IDV as well as long-term flux variations. The IDV time scale does show evidence in favor of an annual modulation, suggesting that the IDV of 0716+714 is dominated by interstellar scintillation. The source underwent a strong outburst phase between mid-2008 and mid-2009; a second intense flare was observed in late 2009, but no correlation between the total flux density and the IDV time scale is found, implying that the flaring state of the source does not have serious implications for the general characteristics of its intra-day variability. However, we find that the inner-jet position angle is changing throughout the years, which could result in an annual modulation noise in the anisotropic ISS model fit. There is also an indication that the lowest IDV amplitudes (rms flux density) correspond to the slowest time scales of IDV, which would be consistent with an ISS origin of the IDV of 0716+714.Comment: 6 pages, 7 figures, accepted for publication in A&A; corrected typos in Table

A seasonal cycle and an abrupt change in the variability characteristics of the intraday variable source S4 0954+65

The BLLac object S4 0954+65 is one of the main targets of the Urumqi monitoring program targeting IntraDay Variable (IDV) sources. Between August 2005 and December 2009, the source was included in 41 observing sessions, carried out at a frequency of 4.8 GHz. The time analysis of the collected light curves, performed by applying both a structure function analysis and a specifically developed wavelet-based algorithm, discovered an annual cycle in the variability timescales, suggesting that there is a fundamental contribution by interstellar scintillation to the IDV pattern of the source. The combined use of the two analysis methods also revealed that there was a dramatic change in the variability characteristics of the source between February and March 2008, at the starting time of a strong outburst phase. The analysis' results suggest that the flaring state of the source coincides with the appearance of multiple timescales in its light curves, indicating that changes in the structure of the relativistically moving emitting region may strongly influence the variability observed on IDV timescales.Comment: 9 pages, 8 figures and 3 tables. Accepted for publication in Astronomy and Astrophysic

A Memetic Analysis of a Phrase by Beethoven: Calvinian Perspectives on Similarity and Lexicon-Abstraction

This article discusses some general issues arising from the study of similarity in music, both human-conducted and computer-aided, and then progresses to a consideration of similarity relationships between patterns in a phrase by Beethoven, from the first movement of the Piano Sonata in A flat major op. 110 (1821), and various potential memetic precursors. This analysis is followed by a consideration of how the kinds of similarity identified in the Beethoven phrase might be understood in psychological/conceptual and then neurobiological terms, the latter by means of William Calvin’s Hexagonal Cloning Theory. This theory offers a mechanism for the operation of David Cope’s concept of the lexicon, conceived here as a museme allele-class. I conclude by attempting to correlate and map the various spaces within which memetic replication occurs

The effect of forearm posture on wrist flexion in computer workers with chronic upper extremity musculoskeletal disorders

<p>Abstract</p> <p>Background</p> <p>Occupational computer use has been associated with upper extremity musculoskeletal disorders (UEMSDs), but the etiology and pathophysiology of some of these disorders are poorly understood. Various theories attribute the symptoms to biomechanical and/or psychosocial stressors. The results of several clinical studies suggest that elevated antagonist muscle tension may be a biomechanical stress factor. Affected computer users often exhibit limited wrist range of motion, particularly wrist flexion, which has been attributed to increased extensor muscle tension, rather than to pain symptoms. Recreational or domestic activities requiring extremes of wrist flexion may produce injurious stress on the wrist joint and muscles, the symptoms of which are then exacerbated by computer use. As these activities may involve a variety of forearm postures, we examined whether changes in forearm posture have an effect on pain reports during wrist flexion, or whether pain would have a limiting effect on flexion angle.</p> <p>Methods</p> <p>We measured maximum active wrist flexion using a goniometer with the forearm supported in the prone, neutral, and supine postures. Data was obtained from 5 subjects with UEMSDs attributed to computer use and from 13 control subjects.</p> <p>Results</p> <p>The UEMSD group exhibited significantly restricted wrist flexion compared to the control group in both wrists at all forearm postures with the exception of the non-dominant wrist with the forearm prone. In both groups, maximum active wrist flexion decreased at the supine forearm posture compared to the prone posture. No UEMSD subjects reported an increase in pain symptoms during testing.</p> <p>Conclusion</p> <p>The UEMSD group exhibited reduced wrist flexion compared to controls that did not appear to be pain related. A supine forearm posture reduced wrist flexion in both groups, but the reduction was approximately 100% greater in the UEMSD group. The effect of a supine forearm posture on wrist flexion is consistent with known biomechanical changes in the distal extensor carpi ulnaris tendon that occur with forearm supination. We infer from these results that wrist extensor muscle passive tension may be elevated in UEMSD subjects compared to controls, particularly in the extensor carpi ulnaris muscle. Measuring wrist flexion at the supine forearm posture may highlight flexion restrictions that are not otherwise apparent.</p

Motor unit potential morphology differences in individuals with non-specific arm pain and lateral epicondylitis

<p>Abstract</p> <p>Background</p> <p>The pathophysiology of non-specific arm pain (NSAP) is unclear and the diagnosis is made by excluding other specific upper limb pathologies, such as lateral epicondylitis or cervical radiculopathy. The purpose of this study was to determine: (i) if the quantitative parameters related to motor unit potential morphology and/or motor unit firing patterns derived from electromyographic (EMG) signals detected from an affected muscle of patients with NSAP are different from those detected in the same muscle of individuals with lateral epicondylitis (LE) and/or control subjects and (ii) if the quantitative EMG parameters suggest that the underlying pathophysiology in NSAP is either myopathic or neuropathic in nature.</p> <p>Methods</p> <p>Sixteen subjects with NSAP, 11 subjects with LE, eight subjects deemed to be at-risk for developing a repetitive strain injury, and 37 control subjects participated. A quantitative electromyography evaluation was completed using decomposition-based quantitative electromyography (DQEMG). Needle- and surface-detected EMG signals were collected during low-level isometric contractions of the extensor carpi radialis brevis (ECRB) muscle. DQEMG was used to extract needle-detected motor unit potential trains (MUPTs), and needle-detected motor unit potential (MUP) and surface detected motor unit potential (SMUP) morphology and motor unit (MU) firing rates were compared among the four groups using one-way analysis of variance (ANOVA). Post hoc analyses were performed using Tukey's pairwise comparisons.</p> <p>Results</p> <p>Significant group differences were found for all MUP variables and for MU firing rate (<it>p</it> < 0.006). The post-hoc analyses revealed that patients with NSAP had smaller MUP amplitude and SMUP amplitude and area compared to the control and LE groups (<it>p </it>< 0.006). MUP duration and AAR values were significantly larger in the NSAP, LE and at-risk groups compared to the control group (<it>p </it>< 0.006); while MUP amplitude, duration and AAR values were smaller in the NSAP compared to the LE group. SMUP duration was significantly shorter in the NSAP group compared to the control group (<it>p </it>< 0.006). NSAP, LE and at-risk subjects had lower mean MU firing rates than the control subjects (<it>p </it>< 0.006).</p> <p>Conclusion</p> <p>The size-related parameters suggest that the NSAP group had significantly smaller MUPs and SMUPs than the control and LE subjects. Smaller MUPs and SMUPs may be indicative of muscle fiber atrophy and/or loss. A prospective study is needed to confirm any causal relationship between smaller MUPs and SMUPs and NSAP as found in this work.</p

Increased Serum and Musculotendinous Fibrogenic Proteins following Persistent Low-Grade Inflammation in a Rat Model of Long-Term Upper Extremity Overuse.

We examined the relationship between grip strength declines and muscle-tendon responses induced by long-term performance of a high-repetition, low-force (HRLF) reaching task in rats. We hypothesized that grip strength declines would correlate with inflammation, fibrosis and degradation in flexor digitorum muscles and tendons. Grip strength declined after training, and further in weeks 18 and 24, in reach limbs of HRLF rats. Flexor digitorum tissues of reach limbs showed low-grade increases in inflammatory cytokines: IL-1β after training and in week 18, IL-1α in week 18, TNF-α and IL-6 after training and in week 24, and IL-10 in week 24, with greater increases in tendons than muscles. Similar cytokine increases were detected in serum with HRLF: IL-1α and IL-10 in week 18, and TNF-α and IL-6 in week 24. Grip strength correlated inversely with IL-6 in muscles, tendons and serum, and TNF-α in muscles and serum. Four fibrogenic proteins, TGFB1, CTGF, PDGFab and PDGFbb, and hydroxyproline, a marker of collagen synthesis, increased in serum in HRLF weeks 18 or 24, concomitant with epitendon thickening, increased muscle and tendon TGFB1 and CTGF. A collagenolytic gelatinase, MMP2, increased by week 18 in serum, tendons and muscles of HRLF rats. Grip strength correlated inversely with TGFB1 in muscles, tendons and serum; with CTGF-immunoreactive fibroblasts in tendons; and with MMP2 in tendons and serum. Thus, motor declines correlated with low-grade systemic and musculotendinous inflammation throughout task performance, and increased fibrogenic and degradative proteins with prolonged task performance. Serum TNF-α, IL-6, TGFB1, CTGF and MMP2 may serve as serum biomarkers of work-related musculoskeletal disorders, although further studies in humans are needed

From evolutionary computation to the evolution of things

Evolution has provided a source of inspiration for algorithm designers since the birth of computers. The resulting field, evolutionary computation, has been successful in solving engineering tasks ranging in outlook from the molecular to the astronomical. Today, the field is entering a new phase as evolutionary algorithms that take place in hardware are developed, opening up new avenues towards autonomous machines that can adapt to their environment. We discuss how evolutionary computation compares with natural evolution and what its benefits are relative to other computing approaches, and we introduce the emerging area of artificial evolution in physical systems