Loss and the Experience of Emotional Distress in Childhood

The objective of this study was to investigate loss and the experience of emotional distress through a series of three studies. In Study 1, results indicated that when controlling for the total number of traumas experienced, children with loss traumas did not differ significantly from children with other types of traumas in terms of the level of PTSD symptoms reported and diurnal cortisol levels. In Study 2, results indicated that youth with loss traumas had significantly higher parent-reported internalizing and externalizing symptoms than control participants. In Study 3, we replicated and extended findings from Study 1 using an independent sample of non-clinic-referred youth. Findings are discussed in terms of how loss events may constitute a traumatic stressor in youth

Post-traumatic stress and age variation in amygdala volumes among youth exposed to trauma

Theoretically, normal developmental variation in amygdala volumes may be altered under conditions of severe stress. The purpose of this article was to examine whether posttraumatic stress moderates the association between age and amygdala volumes in youth exposed to traumatic events who are experiencing symptoms of post-traumatic stress disorder (PTSD). Volumetric imaging was conducted on two groups of youth aged 9–17 years: 28 with exposure to trauma and PTSD symptoms (boys = 15, girls = 13) and 26 matched (age, IQ) comparison youth (Controls; boys = 12, girls = 14). There was a significant group by age interaction in predicting right amygdala volumes. A positive association between age and right amygdala volumes was observed, but only in PTSD youth. These associations with age remained when controlling for IQ, total brain volumes and sex. Moreover, older youth with PTSD symptoms had relatively larger right amygdala volumes than controls. Findings provide evidence that severe stress may influence age-related variation in amygdala volumes. Results further highlight the importance of utilizing age as an interactive variable in pediatric neuroimaging research, in so far as age may act as an important moderator of group differences

D-cycloserine augmentation of exposure-based cognitive behavior therapy for anxiety, obsessive-compulsive, and posttraumatic stress disorders: a systematic review and meta-analysis of individual participant data

Importance: Whether and under which conditions D-cycloserine (DCS) augments the effects of exposure-based cognitive behavior therapy for anxiety, obsessive-compulsive, and posttraumatic stress disorders is unclear. Objective: To clarify whether DCS is superior to placebo in augmenting the effects of cognitive behavior therapy for anxiety, obsessive-compulsive, and posttraumatic stress disorders and to evaluate whether antidepressants interact with DCS and the effect of potential moderating variables. Data Sources: PubMed, EMBASE, and PsycINFO were searched from inception to February 10, 2016. Reference lists of previous reviews and meta-analyses and reports of randomized clinical trials were also checked. Study Selection: Studies were eligible for inclusion if they were (1) double-blind randomized clinical trials of DCS as an augmentation strategy for exposure-based cognitive behavior therapy and (2) conducted in humans diagnosed as having specific phobia, social anxiety disorder, panic disorder with or without agoraphobia, obsessive-compulsive disorder, or posttraumatic stress disorder. Data Extraction and Synthesis: Raw data were obtained from the authors and quality controlled. Data were ranked to ensure a consistent metric across studies (score range, 0-100). We used a 3-level multilevel model nesting repeated measures of outcomes within participants, who were nested within studies. Results: Individual participant data were obtained for 21 of 22 eligible trials, representing 1047 of 1073 eligible participants. When controlling for antidepressant use, participants receiving DCS showed greater improvement from pretreatment to posttreatment (mean difference, -3.62; 95% CI, -0.81 to -6.43; P = .01; d = -0.25) but not from pretreatment to midtreatment (mean difference, -1.66; 95% CI, -4.92 to 1.60; P = .32; d = -0.14) or from pretreatment to follow-up (mean difference, -2.98, 95% CI, -5.99 to 0.03; P = .05; d = -0.19). Additional analyses showed that participants assigned to DCS were associated with lower symptom severity than those assigned to placebo at posttreatment and at follow-up. Antidepressants did not moderate the effects of DCS. None of the prespecified patient-level or study-level moderators was associated with outcomes. Conclusions and Relevance: D-cycloserine is associated with a small augmentation effect on exposure-based therapy. This effect is not moderated by the concurrent use of antidepressants. Further research is needed to identify patient and/or therapy characteristics associated with DCS response.2018-05-0

PSYCHOLOGICAL INQUIRY AND THE ROLE OF WORLD VIEWS AUTHOR’S NOTE:

ABSTRACT: A variety of world models have influenced psychological inquiry. However, recent theoretical analyses of the field have argued that the lack of a single metatheoretical framework in which to base psychological inquiry may have severe negative consequences. In this paper I review three distinctive world views which have influenced psychological inquiry and develop the idea that, at least at this point in the history of psychology, the use of multiple metatheoretical perspectives may be beneficial. Specifically, I suggest that using various metatheoretical views may minimize the perpetuation of limited systems and develop a point of view for thinking about metatheoretical pluralism from several philosophical/intellectual traditions. Moreover, I argue that acknowledging the viability and utility of multiple metatheoretical perspectives does not necessarily resign psychology to perpetual disunification or fragmentation. Imagine Ptolemy’s dismay if he could have reviewed Kepler’s three laws of planetary motion. Kepler’s first law states that the planets move in elliptical orbits. Ptolemy, like the excellent second century astronomer that he was, “knew” that planetary motion must be circular or compounds of circles (i.e., epicycles). Certain metatheoretical assumptions about the nature of reality were in vogue i

The Prevalence And Incremental Validity Of Identity Problem Symptoms In A High School Sample.

This paper examines the expression, prevalence, and incremental validity of identity problem symptoms in adolescence. A sample of high school students (N = 140) aged 15-18 completed measures of identity problem symptoms, identity status, and psychological symptom severity. Findings suggested that 14.3% would meet DSM IV criteria for identity problem. Identity problem symptoms predicted psychological symptom scores beyond identity status, and identity status accounted for substantially less variance in psychological symptom severity when controlling for identity problem symptoms. Additional research on the relationship between identity problems and psychological adjustment is needed and greater attention to the role of identity issues in clinical practice is warranted

A Cross-Sectional Evaluation Of The Factorial Invariance Of Anxiety Sensitivity In Adolescents And Young Adults

This study examined the cross-sectional factorial invariance of anxiety sensitivity in an ethnically diverse sample of adolescents (n=173; mean age 15.5 years) and young adults (n=291; mean age 20.1 years). Research in adult and youth samples suggests that anxiety sensitivity is best understood as a hierarchical construct with several lower-order factors. Factor models based on previous research using both adult and youth samples were compared and a hierarchical model with three lower-order factors provided the best fit to the data. Results supported the hypothesis that the factor structure of the Anxiety Sensitivity Index was invariant across age and gender. The factor scores also demonstrated differential correlations with symptoms of anxiety and depression. Results are discussed with regard to construct validation and understanding the structure of anxiety sensitivity in youth. © 2004 Elsevier Ltd. All rights reserved