16,268 research outputs found
Uranium in the eastern margin of western Siberian plate, or how to overcome crisis of uranium
Теоретические построения [5], свидетельствующие о катагенно-осадочном, эксфильтрационном происхождении железных руд Западно-Сибирского бассейна являются дополнительным фактором принципиальной возможности глубинного происхождения не только радиоактивных металлов, но и ванадия, марганца, благородных металлов и железа. Theoretical constructions [5], which provide evidence of catagenic-aqueous, exfiltration origin of ores of Western Siberian basin, are an additional attribute of principal opportunity for deep seated origin of not only radioactive metals, but also of vanadium, manganese, noble metals and ferrum
Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions
The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially contributing to vascular cell interactions in inflammation and atherosclerosis. In this report, we summarize our findings on the effects of lipid mediators and lipid-lowering drugs. Exposure of endothelial cells to oxidized low density lipoprotein (oxLDL) induces upregulation of ICAM-1 and increases adhesion of monocytic cells expressing Mac-1. Inhibition experiments show that monocytes use distinct ligands, i.e. ICAM-1 and heparan sulfate proteoglycans for adhesion to oxLDL-treated endothelium. An albumin-transferable oxLDL activity is inhibited by the antioxidant pyrrolidine dithiocarbamate (PDTC), while 8-epi-prostaglandin F2 alpha (8-epi-PGF2 alpha) or lysophosphatidylcholine had no effect, implicating yet unidentified radicals. Sequential adhesive! and signaling events lead to the firm adhesion of rolling PMN on activated and adherent platelets, which may occupy areas of endothelial denudation. Shear resistant arrest of PMN on thrombin-stimulated platelets in flow conditions requires distinct regions of Mac-1, involving its interactions with fibrinogen bound to platelet alpha llb beta 3, and with other platelet ligands. Both arrest and adhesion strengthening under flow are stimulated by platelet-activating factor and leukotriene B4, but not by the chemokine receptor CXCR2. We tested whether Mac-1-dependent monocyte adhesiveness is affected by inhibitors of hydroxy-methylglutaryl-Coenzyme A reductase (statins) which improve morbidity and survival of patients with coronary heart disease. As compared to controls, adhesion of isolated monocytes to endothelium ex vivo was increased in patients with hypercholesterolemia. Treatment with statins decreased total and low density lipoprotein (LDL) cholesterol plasma levels, surface expression of Mac-1, and resulted in a dramatic reduction of Mac,mediated monocyte adhesion to endothelium. The inhibition of monocyte adhesion was reversed by mevalonate but not LDL in vitro,indicating that isoprenoid precursors are crucial for adhesiveness of Mac-1. Such effects may crucially contribute to the clinical benefit of statins, independent of cholesterol-lowering, and may represent a paradigm for novel, anti-inflammatory mechanisms of action by this class of drugs
Evidence of Two Distinct Dynamic Critical Exponents in Connection with Vortex Physics
The dynamic critical exponent is determined from numerical simulations
for the three-dimensional (3D) lattice Coulomb gas (LCG) and the 3D XY models
with relaxational dynamics. It is suggested that the dynamics is characterized
by two distinct dynamic critical indices and related to the
divergence of the relaxation time by and
, where is the correlation length and the
wavevector. The values determined are and for the
3D LCG and and for the 3D XY model. It is argued
that the nonlinear exponent relates to , whereas the usual
Hohenberg-Halperin classification relates to . Possible implications for the
interpretation of experiments are pointed out. Comparisons with other existing
results are discussed.Comment: to appear in PR
Detection of a period decrease in NN Ser with ULTRACAM: evidence for strong magnetic braking or an unseen companion?
We present results of high time resolution photometry of the eclipsing
pre-cataclysmic variable NN Ser. We observed 13 primary eclipses of NN Ser
using the high-speed CCD camera ULTRACAM and derived times of mid-eclipse, from
fitting of light curve models, with uncertainties as low as 0.06 s. The
observed rates of period change appear difficult to reconcile with any models
of orbital period change. If the observed period change reflects an angular
momentum loss, the average loss rate is consistent with the loss rates (via
magnetic stellar wind braking) used in standard models of close binary
evolution, which were derived from observations of much more massive cool
stars. Observations of low-mass stars such as NN Ser's secondary predict rates
of ~100 times lower than we observe. We show that magnetic activity-driven
changes in the quadrupole moment of the secondary star (Applegate, 1992) fail
to explain the period change by an order of magnitude on energetic grounds, but
that a light travel time effect caused by the presence of a third body in a
long (~ decades) orbit around the binary could account for the observed changes
in the timings of NN Ser's mid-eclipses. We conclude that we have either
observed a genuine angular momentum loss for NN Ser, in which case our
observations pose serious difficulties for the theory of close binary
evolution, or we have detected a previously unseen low-mass companion to the
binary.Comment: 10 pages, 6 figures. Accepted for publication in MNRA
A novel, aerosol-nanocrystal floating-gate device for non-volatile memory applications
This paper describes the fabrication, and structural and electrical characterization of a new, aerosol-nanocrystal floating-gate FET, aimed at non-volatile memory (NVM) applications. This aerosol-nanocrystal NVM device features program/erase characteristics comparable to conventional stacked gate NVM devices, excellent endurance (>l0^5 P/E cycles), and long-term non-volatility in spite of a thin bottom oxide (55-60Å). In addition, a very simple fabrication process makes this aerosol-nanocrystal NVM device a potential candidate for low cost NVM applications
Scaling behavior in the -relaxation regime of a supercooled Lennard-Jones mixture
We report the results of a molecular dynamics simulation of a supercooled
binary Lennard-Jones mixture. By plotting the self intermediate scattering
functions vs. rescaled time, we find a master curve in the -relaxation
regime. This master curve can be fitted well by a power-law for almost three
decades in rescaled time and the scaling time, or relaxation time, has a
power-law dependence on temperature. Thus the predictions of
mode-coupling-theory on the existence of a von Schweidler law are found to hold
for this system; moreover, the exponents in these two power-laws are very close
to satisfying the exponent relationship predicted by the mode-coupling-theory.
At low temperatures, the diffusion constants also show a power-law behavior
with the same critical temperature. However, the exponent for diffusion differs
from that of the relaxation time, a result that is in disagreement with the
theory.Comment: 8 pages, RevTex, four postscript figures available on request,
MZ-Physics-10
Critical Dynamics of a Vortex Loop Model for the Superconducting Transition
We calculate analytically the dynamic critical exponent measured in
Monte Carlo simulations for a vortex loop model of the superconducting
transition, and account for the simulation results. In the weak screening
limit, where magnetic fluctuations are neglected, the dynamic exponent is found
to be . In the perfect screening limit, . We relate
to the actual value of observable in experiments and find that , consistent with some experimental results
Exact Calculation of the Vortex-Antivortex Interaction Energy in the Anisotropic 3D XY-model
We have developed an exact method to calculate the vortex-antivortex
interaction energy in the anisotropic 3D-XY model. For this calculation, dual
transformation which is already known for the 2D XY-model was extended. We
found an explicit form of this interaction energy as a function of the
anisotropic ratio and the separation between the vortex and antivortex
located on the same layer. The form of interaction energy is at the
small limi t but is proportional to at the opposite limit. This form of
interaction energ y is consistent with the upper bound calculation using the
variational method by Cataudella and Minnhagen.Comment: REVTeX 12 pages, In print for publication in Phys. Rev.
Outlying HII Regions in HI-Selected Galaxies
We present results from the first systematic search for outlying HII regions,
as part of a sample of 96 emission-line point sources (referred to as ELdots -
emission-line dots) derived from the NOAO Survey for Ionization in Neutral Gas
Galaxies (SINGG). Our automated ELdot-finder searches SINGG narrow-band and
continuum images for high equivalent width point sources outside the optical
radius of the target galaxy (> 2 X r25 in the R-band). Follow-up longslit
spectroscopy and deep GALEX images (exposure time > 1000 s) distinguish
outlying HII regions from background galaxies whose strong emission lines
([OIII], Hbeta or [OII]) have been redshifted into the SINGG bandpass. We find
that these deep GALEX images can serve as a substitute for spectroscopic
follow-up because outlying HII regions separate cleanly from background
galaxies in color-color space. We identify seven SINGG systems with outlying
massive star formation that span a large range in Halpha luminosities
corresponding to a few O stars in the most nearby cases, and unresolved dwarf
satellite companion galaxies in the most distant cases. Six of these seven
systems feature galaxies with nearby companions or interacting galaxies.
Furthermore, our results indicate that some outlying HII regions are linked to
the extended-UV disks discovered by GALEX, representing emission from the most
massive O stars among a more abundant population of lower mass (or older) star
clusters. The overall frequency of outlying HII regions in this sample of
gas-rich galaxies is 8 - 11% when we correct for background emission-line
galaxy contamination (~75% of ELdots).Comment: 20 pages, 14 Figures, Accepted by A
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