Bewertung der fertigungstechnologischen Einflussgrößen Laserstrahlschweißen und Sintern auf die Betriebsfestigkeit

Assessment of Manufacturing Technology Influencing Factors Laser Beam Welding and Sintering on the Fatigue Strength. The fatigue strength of a laser beam welded complex engine component was assessed by the notch stress concept applying the reference radius r(ref) = 0.05 mm. By laser beam welding a sintered part and a formed steel sheet were joint together. For the assessment of the fatigue strength of both the laser beam welded joint and the material combination, component-like specimens were manufactured with varying welding parameters and material combinations. Using the results of numerical and experimental investigations on these specimens, a reference SN-curve was derived with which the fatigue strength of the engine component was assessed. A comparison of numerically assessed and experimentally determined fatigue strengths showed a good agreement, which could further be improved by using the method of the highly stressed volume

Repraesentativitaet des natuerlichen Flechtenbewuchses auf Baeumen und des Absterbegrades exponierter Flechten hinsichtlich der einwirkenden Immissionen und hinsichtlich der Waldgefaehrdung durch Immissionen

With 100 refs., 124 tabs., 81 figs.SIGLECopy held by UB/TIB Hannover / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman

Diamond Blackfan anemia: a model for the translational approach to understanding human disease

Diamond Blackfan anemia (DBA) is an inherited bone marrow failure syndrome. As with the other rare inherited bone marrow failure syndromes, the study of these disorders provides important insights into basic biology and, in the case of DBA, ribosome biology; the disruption of which characterizes the disorder. Thus DBA serves as a paradigm for translational medicine in which the efforts of clinicians to manage DBA have informed laboratory scientists who, in turn, have stimulated clinical researchers to utilize scientific discovery to provide improved care. In this review we describe the clinical syndrome Diamond Blackfan anemia and, in particular, we demonstrate how the study of DBA has allowed scientific inquiry to create opportunities for progress in its understanding and treatment