280 research outputs found

    Large Magnetoresistance in Compensated Semimetals TaAs2_2 and NbAs2_2

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    We report large magnetoresistance (MR) at low temperatures in single-crystalline nonmagnetic compounds TaAs2_2 and NbAs2_2. Both compounds exhibit parabolic-field-dependent MR larger than 5Ă—1035\times10^3 in a magnetic field of 9 Tesla at 2 K. The MR starts to deviate from parabolic dependence above 10 T and intends to be saturated in 45 T for TaAs2_2 at 4.2 K. The Hall resistance measurements and band structural calculations reveal their compensated semimetal characteristics. The large MR at low temperatures is ascribed to a resonance effect of the balanced electrons and holes with large mobilities. We also discuss the relation of the MR and samples' quality for TaAs2_2 and other semimetals. We found that the magnitudes of MR are strongly dependent on the samples' quality for different compounds.Comment: 26 pages, 11 figures, 2 table

    Hierarchical Life-Cycle Design of Concrete Structures

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    Concrete structures’ service life lasts decades. In order to deal with all the probable degradations and deteriorations in the whole life span, the concept of concrete structures’ Life-Cycle Design was introduced into China in the 1980s. However, until this day, Life-Cycle Design is still more of a concept to most structure designers and engineers, rather than a practical method. This paper provides a hierarchical method for concrete structures’ Life-Cycle Design, in which the design process is divided into five levels. Safety should be the fundamental requirements for all concrete structures, so as to guarantee a reliable quality. For structures located in severe environments, durability design is necessary so as to ensure the designed service life. Further, when specific economic requirements are set for concrete structures, life-cycle cost (LCC) should be considered carefully in selecting the optimal scheme. Besides, those concrete structures designed to be environmental-friendly should also take into account the specific environmental assessment criteria. Nowadays, user-friendly schemes have attracted increasing attention too; therefore, customers’ demands should also be fully involved in the design process. Considering all the design levels mentioned above, diverse designing criteria are provided accordingly. This paper also uses a road bridge member which exposed to chloride attack in marine environment as an example to illustrate this hierarchical design method. Using the life-cycle-based hierarchical design method, a probable scheme that is safe, durable, economic, environmental friendly, and user friendly is provided

    Tip induced unconventional superconductivity on Weyl semimetal TaAs

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    Weyl fermion is a massless Dirac fermion with definite chirality, which has been long pursued since 1929. Though it has not been observed as a fundamental particle in nature, Weyl fermion can be realized as low-energy excitation around Weyl point in Weyl semimetal, which possesses Weyl fermion cones in the bulk and nontrivial Fermi arc states on the surface. As a firstly discovered Weyl semimetal, TaAs crystal possesses 12 pairs of Weyl points in the momentum space, which are topologically protected against small perturbations. Here, we report for the first time the tip induced superconductivity on TaAs crystal by point contact spectroscopy. A conductance plateau and sharp double dips are observed in the point contact spectra, indicating p-wave like unconventional superconductivity. Furthermore, the zero bias conductance peak in low temperature regime is detected, suggesting potentially the existence of Majorana zero modes. The experimentally observed tunneling spectra can be interpreted with a novel mirror-symmetry protected topological superconductor induced in TaAs, which can exhibit zero bias and double finite bias peaks, and double conductance dips in the measurements. Our work can open a broad avenue in search for new topological superconducting phases from topological Weyl materials and trigger intensive investigations for pursuing Majorana fermions

    Large Magnetoresistance over an Extended Temperature Regime in Monophosphides of Tantalum and Niobium

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    We report extremely large magnetoresistance (MR) in an extended temperature regime from 1.5 K to 300 K in non-magnetic binary compounds TaP and NbP. TaP exhibits linear MR around 1.8Ă—1041.8\times 10^4 at 2 K in a magnetic field of 9 Tesla, which further follows its linearity up to 1.4Ă—1051.4\times 10^5 in a magnetic field of 56 Tesla at 1.5 K. At room temperature the MR for TaP and NbP follows a power law of the exponent about 1.51.5 with the values larger than 300%300\% in a magnetic field of 9 Tesla. Such large MR in a wide temperature regime is not likely only due to a resonance of the electron-hole balance, but indicates a complicated mechanism underneath.Comment: 13 pages, 4 figures; submitted in May 20, 2015; accepted for publicatio

    Social Dimensions in Sustainability Evaluation of Deteriorating Reinforced Concrete Bridges

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    Structural sustainability requires that structural engineering activities should find ways to design and maintain structures that perform as required during their life-cycle considering intergenerational needs. Massive attention has been paid to the economic and environmental evaluation of structures. However, being a completely different discipline from structural engineering, the social dimensions associated with structures were rarely considered in previous studies due to the difficulty in determination and quantification, unavoidable subjectivity and controversy, as well as the lack of historical data. This paper identifies the social impacts induced by engineering activities associated with the deterioration of reinforced concrete structures, and proposes corresponding computational approaches from the structural engineering viewpoint. Utility theory is used herein to measure, normalize and combine different social attributes with consideration of the risk attitudes of decision makers. A case study is performed on a deteriorating reinforced concrete bridge to compare the social performances of different maintenance strategies based on the associated multi-attribute social utility values

    Divergence in function and expression of the NOD26-like intrinsic proteins in plants

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    <p>Abstract</p> <p>Background</p> <p>NOD26-like intrinsic proteins (NIPs) that belong to the aquaporin superfamily are plant-specific and exhibit a similar three-dimensional structure. Experimental evidences however revealed that functional divergence should have extensively occurred among NIP genes. It is therefore intriguing to further investigate the evolutionary mechanisms being responsible for the functional diversification of the NIP genes. To better understand this process, a comprehensive analysis including the phylogenetic, positive selection, functional divergence, and transcriptional analysis was carried out.</p> <p>Results</p> <p>The origination of NIPs could be dated back to the primitive land plants, and their diversification would be no younger than the emergence time of the moss <it>P. patens</it>. The rapid proliferation of NIPs in plants may be primarily attributed to the segmental chromosome duplication produced by polyploidy and tandem duplications. The maximum likelihood analysis revealed that <it>NIPs </it>should have experienced strong selective pressure for adaptive evolution after gene duplication and/or speciation, prompting the formation of distinct <it>NIP </it>groups. Functional divergence analysis at the amino acid level has provided strong statistical evidence for shifted evolutionary rate and/or radical change of the physiochemical properties of amino acids after gene duplication, and DIVERGE2 has identified the critical amino acid sites that are thought to be responsible for the divergence for further investigation. The expression of plant NIPs displays a distinct tissue-, cell-type-, and developmental specific pattern, and their responses to various stress treatments are quite different also. The differences in organization of <it>cis</it>-acting regulatory elements in the promoter regions may partially explain their distinction in expression.</p> <p>Conclusion</p> <p>A number of analyses both at the DNA and amino acid sequence levels have provided strong evidences that plant NIPs have suffered a high divergence in function and expression during evolution, which is primarily attributed to the strong positive selection or a rapid change of evolutionary rate and/or physiochemical properties of some critical amino acid sites.</p

    MGTUNet: An new UNet for colon nuclei instance segmentation and quantification

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    Colorectal cancer (CRC) is among the top three malignant tumor types in terms of morbidity and mortality. Histopathological images are the gold standard for diagnosing colon cancer. Cellular nuclei instance segmentation and classification, and nuclear component regression tasks can aid in the analysis of the tumor microenvironment in colon tissue. Traditional methods are still unable to handle both types of tasks end-to-end at the same time, and have poor prediction accuracy and high application costs. This paper proposes a new UNet model for handling nuclei based on the UNet framework, called MGTUNet, which uses Mish, Group normalization and transposed convolution layer to improve the segmentation model, and a ranger optimizer to adjust the SmoothL1Loss values. Secondly, it uses different channels to segment and classify different types of nucleus, ultimately completing the nuclei instance segmentation and classification task, and the nuclei component regression task simultaneously. Finally, we did extensive comparison experiments using eight segmentation models. By comparing the three evaluation metrics and the parameter sizes of the models, MGTUNet obtained 0.6254 on PQ, 0.6359 on mPQ, and 0.8695 on R2. Thus, the experiments demonstrated that MGTUNet is now a state-of-the-art method for quantifying histopathological images of colon cancer.Comment: Published in BIBM2022(regular paper),https://doi.org/10.1109/BIBM55620.2022.999566
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