Combinando Linked Data con servicios geoespaciales

La Web de Linked Data supone un nuevo paradigma que pretende explotar la Web como un espacio global de información. La aplicación de los principios de esta nueva Web a la información geoespacial superará la integración de información tradicional, logrando una articulación semántica de los datos que haga desaparecer los silos de datos presentes en las actuales Infraestructuras de Datos Espaciales. Ante esta propuesta, en este artículo se describe el trabajo desarrollado en el marco de un caso de uso utilizando una parte de los datos del SIGNA. En este caso de uso se ha llevado a cabo un proceso de generación y publicación de los mencionados datos conforme a los principios de Linked Data y estos se combinan con diversos servicios de la IDEE y CartoCiudad para explotar el componente geoespacial

Régimen de los actos jurídicos entre vivos otorgados con anterioridad a la declaración de demencia : arts. 473 y 474 del Código Civil

Fil: Sánchez de Bustamante, Miguel. Universidad de Buenos Aires. Facultad de Derecho. Cátedra Derecho Civil. Buenos Aires, Argentin

Producción de Aguacate en la localidad Chapa de Nuevo, municipio de Salvador Escalante Michoacán, México

El sector agroalimentario mexicano se posesiona como el doceavo proveedor de alimentos para el mundo. La producción de aguacate se realiza en 27 estados de la república mexicana, donde el estado de Michoacán aporta el 80.3% de la producción nacional. El estado de Michoacán aporta el 12.9% del valor nacional de la producción agrícola, lo que permite al estado ocupar el primer lugar nacional. En las regiones una vez que se establece un sistema de producción comienzan actuar las relaciones productivas las cuales establecen un modelo específico para ésta. El objetivo del trabajo es caracterizar los sistemas de producción de aguacate en la localidad de Chapa de Nuevo en el municipio de Salvador Escalante en el estado de Michoacán México. El trabajo se realizó en el municipio de Salvador Escalante que ocupa el 0.83% de la superficie del estado, en la localidad de Chapa Nuevo, con productores de aguacate. Se realizó una investigación de alcance exploratorio. Se realizo un muestreo por intención (técnica de bola de nieve). Donde las unidades muéstrales van escogiéndose, sucesivamente, a partir de las referencias aportadas por los sujetos a los que ya se ha accedido y se les aplico una encuesta de tipo semi estructurada. A la información generada se analizó utilizando estadística descriptiva. Se entrevistaron a 38 hombres y tres mujeres dentro la muestra seleccionada por conveniencia. La edad promedio de los entrevistados fue de 47.56 años. La media de años que tienen dedicándose a la producción de aguacate es de 24.34 años. El 53.7% de los encuestados tienen primaria, 24.4% cuentan con estudios de secundaria; 14.6% tienen estudios de preparatoria y únicamente el 7.3% realizaron estudios de licenciatura. La superficie media que tienen los productores es de 4.32 hectáreas y éstas tienen en producción 14.19 años. El financiamiento es considerado por el 22% de los encuestados en el rango de muy poco importante a medianamente importante, el 41.5% consideran al financiamiento como importante y el 24.4% consideran muy importante. La utilización de fertilizantes químicos u orgánicos, así como insecticidas, herbicidas. El 65.9% de los encuestados respondieron que es importante y 34.1% restante lo consideran muy importante. A la importancia de contar con instalaciones el 65.9% contesto importante, 29.3% muy importante y 4.9% medianamente importante. Finalmente, al uso de tecnologías para el cuidado y manejo agronómico de las huertas la principal opción seleccionada fue la de importante con el 61%, seguida con el 24.4% de muy importante, mientras que medianamente importante y poco importante fueron seleccionadas por 7.3% de los entrevistados. Lo que permite concluir que la producción de aguacate del grupo encuestado se caracterizada por ser productores de pequeña escala menor de 5 has con un manejo de tipo convencional. Consideran al financiamiento importante, pero no tienen acceso al mismo, utilizan fertilizantes, herbicidas, insecticidas orgánicos y químicos lo que permite que estos productores presenten una productividad media

ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries

This review summarizes the last decade of work by the ENIGMA (Enhancing NeuroImaging Genetics through Meta Analysis) Consortium, a global alliance of over 1400 scientists across 43 countries, studying the human brain in health and disease. Building on large-scale genetic studies that discovered the first robustly replicated genetic loci associated with brain metrics, ENIGMA has diversified into over 50 working groups (WGs), pooling worldwide data and expertise to answer fundamental questions in neuroscience, psychiatry, neurology, and genetics. Most ENIGMA WGs focus on specific psychiatric and neurological conditions, other WGs study normal variation due to sex and gender differences, or development and aging; still other WGs develop methodological pipelines and tools to facilitate harmonized analyses of "big data" (i.e., genetic and epigenetic data, multimodal MRI, and electroencephalography data). These international efforts have yielded the largest neuroimaging studies to date in schizophrenia, bipolar disorder, major depressive disorder, post-traumatic stress disorder, substance use disorders, obsessive-compulsive disorder, attention-deficit/hyperactivity disorder, autism spectrum disorders, epilepsy, and 22q11.2 deletion syndrome. More recent ENIGMA WGs have formed to study anxiety disorders, suicidal thoughts and behavior, sleep and insomnia, eating disorders, irritability, brain injury, antisocial personality and conduct disorder, and dissociative identity disorder. Here, we summarize the first decade of ENIGMA's activities and ongoing projects, and describe the successes and challenges encountered along the way. We highlight the advantages of collaborative large-scale coordinated data analyses for testing reproducibility and robustness of findings, offering the opportunity to identify brain systems involved in clinical syndromes across diverse samples and associated genetic, environmental, demographic, cognitive, and psychosocial factors

The Changing Landscape for Stroke\ua0Prevention in AF: Findings From the GLORIA-AF Registry Phase 2

Background GLORIA-AF (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation) is a prospective, global registry program describing antithrombotic treatment patterns in patients with newly diagnosed nonvalvular atrial fibrillation at risk of stroke. Phase 2 began when dabigatran, the first non\u2013vitamin K antagonist oral anticoagulant (NOAC), became available. Objectives This study sought to describe phase 2 baseline data and compare these with the pre-NOAC era collected during phase 1. Methods During phase 2, 15,641 consenting patients were enrolled (November 2011 to December 2014); 15,092 were eligible. This pre-specified cross-sectional analysis describes eligible patients\u2019 baseline characteristics. Atrial fibrillation disease characteristics, medical outcomes, and concomitant diseases and medications were collected. Data were analyzed using descriptive statistics. Results Of the total patients, 45.5% were female; median age was 71 (interquartile range: 64, 78) years. Patients were from Europe (47.1%), North America (22.5%), Asia (20.3%), Latin America (6.0%), and the Middle East/Africa (4.0%). Most had high stroke risk (CHA2DS2-VASc [Congestive heart failure, Hypertension, Age  6575 years, Diabetes mellitus, previous Stroke, Vascular disease, Age 65 to 74 years, Sex category] score  652; 86.1%); 13.9% had moderate risk (CHA2DS2-VASc = 1). Overall, 79.9% received oral anticoagulants, of whom 47.6% received NOAC and 32.3% vitamin K antagonists (VKA); 12.1% received antiplatelet agents; 7.8% received no antithrombotic treatment. For comparison, the proportion of phase 1 patients (of N = 1,063 all eligible) prescribed VKA was 32.8%, acetylsalicylic acid 41.7%, and no therapy 20.2%. In Europe in phase 2, treatment with NOAC was more common than VKA (52.3% and 37.8%, respectively); 6.0% of patients received antiplatelet treatment; and 3.8% received no antithrombotic treatment. In North America, 52.1%, 26.2%, and 14.0% of patients received NOAC, VKA, and antiplatelet drugs, respectively; 7.5% received no antithrombotic treatment. NOAC use was less common in Asia (27.7%), where 27.5% of patients received VKA, 25.0% antiplatelet drugs, and 19.8% no antithrombotic treatment. Conclusions The baseline data from GLORIA-AF phase 2 demonstrate that in newly diagnosed nonvalvular atrial fibrillation patients, NOAC have been highly adopted into practice, becoming more frequently prescribed than VKA in Europe and North America. Worldwide, however, a large proportion of patients remain undertreated, particularly in Asia and North America. (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients With Atrial Fibrillation [GLORIA-AF]; NCT01468701

Respiratory Complications Are the Main Predictors of 1-Year Mortality in Patients with Hip Fractures: The Results from the Alzira Retrospective Cohort Study

Resumen: Introducción: Las fracturas de cadera representan un desafío importante para las personas mayores dada su Alta incidencia y tasa de mortalidad a un año. El objetivo de este estudio fue identificar las principales predictores de mortalidad a un año en adultos mayores hospitalizados por fracturas de cadera. Métodos: Realizamos un estudio de cohorte retrospectivo en el que participaron adultos de 70 años o más que ingresaron en el hospital para fracturas de cadera por fragilidad entre el 1 de enero de 2014 y el 31 de diciembre de 2021. Un total de 3229 pacientes fueron reclutados, y 846 (26,2%) experimentaron mortalidad al año. Resultados: complicaciones respiratorias (HR 2,42, IC 95% 1,42–4,14; p = 0,001) fueron los predictores más significativos de mortalidad a un año, seguido del reingreso hospitalario (HR 1,96, IC 95% 1,66-2,32; p < 0,001), el sexo masculino (HR 1,88, IC 95% 1,46–2,32; p < 0,001), complicaciones cardíacas (HR 1,88, IC 95% 1,46-2,32; p < 0,001) y un diagnóstico de demencia al ingreso (HR 1,37, IC95% 1,13-1,66; p = 0,001). El índice Charlson y el índice americano El sistema de clasificación del estado físico de la Sociedad de Anestesiólogos también aumentó significativamente el riesgo de mortalidad. Por el contrario, niveles más altos de hemoglobina al ingreso y albúmina elevada al alta. redujo significativamente el riesgo de mortalidad. Conclusiones: La tasa de mortalidad a un año es sustancial. en adultos mayores con fracturas de cadera que ingresan en una unidad de ortogeriatría. La Apropiada Manejo de la anemia, los trastornos nutricionales y la comorbilidad al ingreso y durante el seguimiento. podría potencialmente mitigar la mortalidad a largo plazo después de fracturas de cadera. Palabras clave: fractura de cadera; adultos mayores; Mortalidad a 1 año; factores de riesgo; atención ortogeriátrica; fragilidad fracturasQ2Q2Abstract: Introduction: Hip fractures pose a significant challenge for older individuals given their high incidence and one-year mortality rate. The objective of this study was to identify the primary predictors of one-year mortality in older adults hospitalized for hip fractures. Methods: We conducted a retrospective cohort study involving adults aged 70 years or older who were admitted to the hospital for fragility hip fractures between 1 January 2014 and 31 December 2021. A total of 3229 patients were recruited, with 846 (26.2%) experiencing one-year mortality. Results: Respiratory complications (HR 2.42, 95%CI 1.42–4.14; p = 0.001) were the most significant predictors of one-year mortality, followed by hospital readmission (HR 1.96, 95%CI 1.66–2.32; p < 0.001), the male sex (HR 1.88, 95%CI 1.46–2.32; p < 0.001), cardiac complications (HR 1.88, 95%CI 1.46–2.32; p < 0.001), and a diagnosis of dementia at admission (HR 1.37, 95%CI 1.13–1.66; p = 0.001). The Charlson Index and the American Society of Anesthesiologists physical status classification system also significantly increased the mortality risk. Conversely, higher hemoglobin levels at admission and elevated albumin at discharge significantly reduced the mortality risk. Conclusions: The one-year mortality rate is substantial in older adults with hip fractures who are admitted to an orthogeriatric unit. The appropriate management of anemia, nutritional disorders, and comorbidity at admission and during the followup could potentially mitigate long-term mortality after hip fractures. Keywords: hip fracture; older adults; 1-year mortality; risk factors; orthogeriatric care; fragility fractureshttps://orcid.org/0000-0001-5832-0603https://scholar.google.com/citations?user=MrICwaMAAAAJ&hl=enhttps://scienti.minciencias.gov.co/cvlac/visualizador/generarCurriculoCv.do?cod_rh=0001429659Revista Internacional - IndexadaS

Examining the online repurchase behavioral intentions of online shoppers in Lazada: A study on how pre-purchase user perceptions of attributes, pre-purchase user attitudes, and perceived benefits affect repurchase intention

Online retailers such as Lazada have staked their claim as business giants in modern times. This study aims to examine the online repurchase behavioral intention of Lazada users, and which factors are significant to determining these behaviors. To examine these factors, the study utilizes a quantitative research method which uses linear regression analysis to test the data gathered from 388 respondents. The findings of the study show that pre-purchase user attributes are determinants of repurchase intention in terms of perceived usefulness, while the variables of perceived ease of use, perceived risk, and perceived value are not influential predictors of repurchase intention, meaning that these variables do not affect the repurchase intention of Lazada shoppers. The variables of perceived benefit, and pre-purchase user attitudes can drive customers to repurchase from Lazada. These findings were mostly in line with answers from industry experts regarding their opinions on the influence of the stated variables on online repurchase intention. It is advisable for online retailers to implement features that enhance perceived usefulness, trust, privacy concern, satisfaction with process quality, and satisfaction with outcome quality. Features that address these factors include 2-factor authentication, checking product packaging, and regularly engaging with customers to improve trust and satisfaction with Lazada. This study contributes to knowledge of determining customer repurchase intention

Evolutionary PTEN gene divergence underpins the remodeling of plant vacuolar compartments

Membrane fusion and fission are fundamental processes in sustaining cellular compartmentalization. Fission of a lipid bilayer requires a furrow formation that brings membranes in close proximity prior to a contiguous membrane cleavage. Although plant ancestors abandoned cleavage furrow-mediated cytokinesis more than 500 million years ago, here we show that plants still employ this mechanical principle to divide embryonic vacuoles. The evolutionary divergence in PHOSPHATASE AND TENSIN HOMOLOG DELETED ON CHROMOSOME TEN (PTEN) enzymes was required to coordinate this process, as Arabidopsis loss-of-function pten2a pten2b mutants contain hyper compartmentalized embryonic vacuoles. In contrast, PTEN2 overexpression hinders lytic and secretion cellular pathways downstream of TGN in xylem cells. These processes are critical for the formation of secondary cell walls in xylem cells and depend on a poorly characterized and evolutionarily novel N-terminal domain in PTEN2s. The PTEN2 subfamily appeared with the emergence of the Phragmoplastophyta clade, when vacuolar compartments enlarged and cleavage furrow-mediated cytokinesis became extinct. Together, our work suggests that the evolutionary innovation of the PTEN family is conserved across terrestrial plants and central to vacuolar remodelling