El reasentamiento de jóvenes refugiados en Australia: experiencias y resultados en el tiempo

Los resultados de un estudio longitudinal de experiencias de reasentamiento a largo plazo de jóvenes refugiados que viven en Melbourne muestran que las experiencias de los refugiados —tanto antes como después del reasentamiento— continúan influyendo en las oportunidades y los resultados muchos años después de la llegada

Cell surface immobilization of GABAARs in cerebellar granule cells depends on the M3/M4 cytoplasmatic loop of the alpha 1 subunit

Gamma-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the vertebrate brain. The localization of GABA receptors type A (GABAARs) at strategically located domains of the neuronal membrane is of vital importance for fast inhibitory synapse transmission efficacy. We have shown before that the lateral mobility of GABAARs depends on subunit composition of the complex. To study the lateral mobility of GABAARs in living, cultured neurons, we transfected cerebellar granule cells with either the complete 1 GABAAR subunit or with a truncation of the 1 subunit that lacks the major intracellular loop (M3/M4). We examined the location and lateral mobility of receptors containing both versions of the 1 subunit in living neurons. From fluorescence recovery after photobleaching experiments we present novel evidences that the intracellular M3/M4 loop of the 1 subunit restricts the lateral mobility of GABAARs when expressed in neurons. In addition, our immunocytochemical studies suggested that receptors containing the truncated subunit seem to be unable to reach synaptic localizations. Here we show for the first time that the 1 intracellular loop (M3/M4) domain has a relevant role in controlling the lateral mobility of GABAARs in neurons, and we believe that this is a novel and important contribution in neurobiology of GABAA receptors

Navigating precarious terrains: Reconceptualising refugee youth settlement

Settlement is widely understood as the final stage of the refugee journey: a durable solution to forced displacement and a stable environment in which former refugees can rebuild their lives. However, settlement is shaped by rapidly changing socio-political forces producing contingent, unpredictable, and even hostile environments. This article draws upon Vigh’s concept of social navigation to reconceptualize settlement as a continuation of a fraught journey in which refugee settlers must continually seek new strategies to pursue viable futures. We illustrate with an in-depth case study of the settlement journey of one refugee-background young man over his first eight years in Melbourne, Australia

Calidad de agua en el Río Uruguay en el tramo Tortuga Alegre-Puerto Yeruá utilizando bioindicadores (Diatomeas)

Se consideró relevante monitorear y caracterizar la calidad del agua en un tramo del río Uruguay,utilizando diatomeas, como bioindicadoras, su relación con factores fisicoquímicos y plaguicidas, en un ciclo anual. Los máximos valores de los parámetros fisicoquímicos y DBO se registraron en su mayoría en La Verde, Benito Lejerén y Yuquerí Chico. Por otro lado, las diatomeas determinadas en estos sitios, fueron tolerantes a altos niveles de contaminación, demostrando así, que son excelentes bioindicado-ras de la calidad del agua. Se identificaron 285 taxones distribuidos en los géneros Nitzschia, Navicula, Gomphonema, entre otros. El índice de Diatomeas Pampeano, resultó apropiado para la evaluación de la calidad de agua en este tramo del río. Sin embargo, en algunos sitios se encontró dominancia de es-pecies que no cuentan con un valor asignado de IDP, por lo tanto, se plantea la necesidad de elaborar un nuevo índice local. Se determinó la presencia de plaguicidas organoclorados a lo largo de todo el año, alcanzando niveles muy elevados en el cuarto muestreo. Resulta importante, que los programas de monitoreo de calidad de agua se complementen además, con la incorporación de bioindicadores, lo cual, sería de gran utilidad para el asesoramiento del estado trófico de ríos.Fil: Novoa, Martin David. Universidad Nacional de Entre Rios. Facultad de Ciencias de la Alimentacion. Laboratorio de Investigacion de Residuos En Alimentos.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Raviol, Fabricio H.. Universidad Nacional de Entre Rios. Facultad de Ciencias de la Alimentacion. Laboratorio de Investigacion de Residuos En Alimentos.; ArgentinaFil: Munitz, Martín Sebastián. Universidad Nacional de Entre Rios. Facultad de Ciencias de la Alimentacion. Laboratorio de Investigacion de Residuos En Alimentos.; ArgentinaFil: Medina, María Belén. Universidad Nacional de Entre Rios. Facultad de Ciencias de la Alimentacion. Laboratorio de Investigacion de Residuos En Alimentos.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Subovich, Gladys Ester. Universidad Nacional de Entre Rios. Facultad de Ciencias de la Alimentacion. Laboratorio de Investigacion de Residuos En Alimentos.; ArgentinaFil: Parma, Fernando Andrés. Universidad Nacional de Entre Rios. Facultad de Ciencias de la Alimentacion. Laboratorio de Investigacion de Residuos En Alimentos.; ArgentinaFil: Williman, Celia. Universidad Nacional de Entre Rios. Facultad de Ciencias de la Alimentacion. Laboratorio de Investigacion de Residuos En Alimentos.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Page, Lucas Matías. Universidad Nacional de Entre Rios. Facultad de Ciencias de la Alimentacion. Laboratorio de Investigacion de Residuos En Alimentos.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Diaz Velez, Marcela. Universidad Nacional de Entre Rios. Facultad de Ciencias de la Alimentacion. Laboratorio de Investigacion de Residuos En Alimentos.; Argentin

Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine

The target of neutralizing antibodies that protect against influenza virus infection is the viral protein HA. Genetic and antigenic variation in HA has been used to classify influenza viruses into subtypes (H1–H16). The neutralizing antibody response to influenza virus is thought to be specific for a few antigenically related isolates within a given subtype. However, while heterosubtypic antibodies capable of neutralizing multiple influenza virus subtypes have been recently isolated from phage display libraries, it is not known whether such antibodies are produced in the course of an immune response to influenza virus infection or vaccine. Here we report that, following vaccination with seasonal influenza vaccine containing H1 and H3 influenza virus subtypes, some individuals produce antibodies that cross-react with H5 HA. By immortalizing IgG-expressing B cells from 4 individuals, we isolated 20 heterosubtypic mAbs that bound and neutralized viruses belonging to several HA subtypes (H1, H2, H5, H6, and H9), including the pandemic A/California/07/09 H1N1 isolate. The mAbs used different VH genes and carried a high frequency of somatic mutations. With the exception of a mAb that bound to the HA globular head, all heterosubtypic mAbs bound to acid- sensitive epitopes in the HA stem region. Four mAbs were evaluated in vivo and protected mice from challenge with influenza viruses representative of different subtypes. These findings reveal that seasonal influenza vaccination can induce polyclonal heterosubtypic neutralizing antibodies that cross-react with the swine-origin pandemic H1N1 influenza virus and with the highly pathogenic H5N1 virus

Blue Genes : Synopsis of the workshop organized by ICM-CSIC and BAU to increase engagement and collaboration for Our Ocean and Waters

7 pagesOn October 27th, 2022, the Institut de Ciències del Mar (ICM-CSIC), a marine research institution located in Barcelona, and the College of Arts & Design of Barcelona (BAU), a higher-education centre specialized in arts and design, co-organized the first Blue Genes meeting. This meeting took place virtually in a 3-hour workshop format and counted with more than 50 participants from different locations. Its main goal was to explore in a co-creative way how to reinforce and empower the engagement of people, particularly teenagers and young adults, with our Ocean and Waters and increase networking and collaboration. This meeting was the first workshop of a series of planned activities under the Blue Genes initiativePeer reviewe

The persistence of predictors of wellbeing among refugee youth eight years after resettlement in Melbourne, Australia

This short report assesses the predictors of subjective health and happiness among a cohort of refugee youth over their first eight years in Australia. Five waves of data collection were conducted between 2004 (n=120) and 2012–13 (n=51) using mixed methods. Previous schooling,self-esteem, moving house in the previous year, a supportive social environment, stronger ethnic identity and perceived discrimination were significant predictors of wellbeing after adjusting for demographic and pre-migration factors. When compared with a previous analysis of this cohort over their first three years of settlement, experiences of social exclusion still have a significant impact on wellbeing eight years after arriving in Australia. This study contributes to mounting evidence in support of policies that discourage discrimination and promote social inclusion and cultural diversity and which underpin the wellbeing of resettled refugee youth

Through their eyes: seeing experiences of settlement in photographs taken by refugee background youth in Melbourne, Australia

Although “refugees” are frequently represented in visual media, it is predominantly as the central subject matter and rarely are they positioned as the photographers of their own journeys. In this article we present photographic images that have been taken by refugee background youth portraying their experiences of the first years of settlement in Australia. We consider how, in our longitudinal research conducted with 120 refugee background youth, visual materials can provide equally important yet different insights in comparison to written or spoken narratives on the experiences of refugee settlement. Through an examination of over 1,000 photos taken by these youth, we explore the ways in which they portrayed their early experiences of external suburban settlement environments and their depictions of interior spaces and home-making practices. We discuss how these visual insights capture an alternative way of seeing the experiences of becoming at home as the youth become emplaced post-resettlement in Australia. We argue that the photographs taken by these refugee background youth illustrate how visual methods and materials can provide equally important but often overlooked insights into early settlement experiences. Importantly, the photographic images offer a way of portraying the people, places and sentiments that are central to the everyday lives of refugee background youths in ways that oral and written narratives can not

Experiences of resettled refugees during the 2011 Queensland floods

With projected climatic changes it is expected that refugees and other forced migrants will increasingly spend protracted amounts of time in transit countries or will resettle in locations that experience ecological vulnerability. A submission to the Queensland Floods Commission Inquiry 2011 by MDA reported that the floods displaced about 70 refugee client families and that 30 families had ongoing complex needs at the time of the submission. The findings reported in this chapter are derived from a follow-up of a cohort of men from refugee backgrounds who participated in the 2008–10 SettleMEN project. The chapter provides an insight into the experiences of refugee migrants who experience environmental disaster in a site of settlemen