Functional outcome of JESS fixation and bone grafting in distal tibial plafond-pilon fracture: a prospective study

Background: The Pilon fractures are one of the most difficult to treat. Fracture known as “orthopedicians nightmare”. The incidence of complications following ORIF of pilon ranges from 10-55% and other complication are infection, loss of reduction, secondary arthrosis. In these circumstances JESS and Bone grafting is cost effective and less hospitalization. Our aim was to evaluate in the functional outcome of JESS fixation and bone grafting in distal tibial plafond- pilon fracture using Olerud and Molander score.Methods: The JESS fixation and bone grafting was used for pilon fracture in 30 patients, 24 male and 6 female. Mean age 44 years range (18-60 years). Fractures caused by fall and RTA. All were treated with JESS fixation and bone grafting. the patients were assessed clinically and radiographically at regular interval of 1 month and later 2 months interval. Outcome was assessed using Olerud and Molander score. Complications were recorded.Results: 12 patients had Ruedi and Allgower type II fracture and 18 patients had type III fracture. After 9 month of follow up midterm OMAS score- 11.766 was achieved. Outcomes were good in 71.25% and fair results in 50.83% respectively. The complication seen was residual ankle pain in 6.66% patients and implant failure in 13.33%.Conclusions: Fixation of pilon fracture with JESS and bone grafting is associated with good functional outcome in type II and fair in type III pilon fracture. The incidence of complications high in type III pilon fracture.

Effects on blood gas and haematological parameters during butorphanoldexmedetomidine- tiletamine-zolazepam anaesthesia in cats

The present study was undertaken to evaluate the effects of butorphanol, dexmedetomidine, tiletamine and zolazepam anaesthesia on blood gas and haematological parameters in cats. These parameters were monitored before anaesthetic induction and 10 minutes following anaesthetic induction. Statistical analysis revealed that no significant changes exist and the parameters were within the normal reference range for cats. Therefore, this anaesthetic technique could be employed safely for elective surgery in cats

Effects of intravenous lignocaine on anaesthetic parameters in cattle under dexmedetomidine-butorphanol-ketaminemidazolam- isofluraneanaesthesia

The present study was conducted for clinical evaluation of a multimodal anaesthetic protocol using butorphanol-dexmedetomidine-midazolam-ketamine-isoflurane and lignocaine continuous rate infusion (CRI) in six cross-bred female cattle. Preanaesthetics used were butorphanol and dexmedetomidine which were administered intravenously at dose rates of 0.05 mg/kg and 1 μg/ kg body weight, respectively. Ketamine and midazolam were intravenously administered at dose rates of 4.0 and 0.2 mg/kg body weight respectively, to induce anaesthesia. Isoflurane was used to maintain anaesthesia after endotracheal intubation, at a concentration of 1.05 ± 0.97 per cent concentration in 100 per cent oxygen using a large animal anaesthesia machine. Simultaneously, intravenous lignocaine was administered at a bolus dose of 2 mg/kg body weight followed by a CRI of 3 mg/kg body weight/hour using a volumetric infusion pump. Isoflurane sparing effect of intravenous lignocaine reduced the required concentration of isoflurane for maintenance. The third plane of surgical anaesthesia was maintained and various surgical procedures were done. Recovery was smooth. Other than the mild regurgitation of ruminal fluid in an animal, no anaesthetic complications were noticed

B-mode and Doppler ultrasound features of mammary neoplasms and their comparison with normal mammary glands in dogs

Canine mammary neoplasms are naturally occurring non-homogenous group of tumours with many resemblances to human breast cancer. In female dogs mammary tumours are of great clinical relevance due to the high prevalence and mortality rate, which varies according to the histopathological classification and clinical stage. The aim of the study was to compare the ultrasonographic features of the normal mammary gland with benign and malignant mammary neoplasms in dogs, through assessed by B-mode and Doppler mode ultrasonography. Ultrasonographic examination of seven normal mammary glands along with six benign and 12 malignant mammary neoplasms were performed. Among the parameters evaluated by B-Mode ultrasonography, significant differences were found (p < 0.01) in the tumour margin and invasiveness of neoplasms, where malignant tumours were invasive with uncircumscribed margin. Significant difference was also found in the presence of posterior acoustic enhancement (p<0.05) between benign and malignant mammary neoplasms. Elevated peak systolic velocity of blood flow within the tumour vessels in malignant mammary neoplasm was the only feature assessed with Doppler mode having significant difference

Oligo(p-phenylene-ethynylene)-derived super-π-gelators with tunable emission and self-assembled polymorphic structures

Linear π-conjugated oligomers are known to form organogels through noncovalent interactions. Herein, we report the effect of π-repeat units on the gelation and morphological properties of three different oligo(p-phenylene-ethynylene)s: OPE3, OPE5, and OPE7. All of these molecules form fluorescent gels in nonpolar solvents at low critical gel concentrations, thereby resulting in a blue gel for OPE3, a green gel for OPE5, and a greenish yellow gel for OPE7. The molecule–molecule and molecule–substrate interactions in these OPEs are strongly influenced by the conjugation length of the molecules. Silicon wafer suppresses substrate–molecule interactions whereas a mica surface facilitates such interactions. At lower concentrations, OPE3 formed vesicular assemblies and OPE5 gave entangled fibers, whereas OPE7 resulted in spiral assemblies on a mica surface. At higher concentrations, OPE3 and OPE5 resulted in super-bundles of fibers and flowerlike short-fiber agglomerates when different conditions were applied. The number of polymorphic structures increases on increasing the conjugation length, as seen in the case of OPE7 with n=5, which resulted in a variety of exotic structures, the formation of which could be controlled by varying the substrate, concentration, and humidity

Self-assembly of tripodal squaraines: cation-assisted expression of molecular chirality and change from spherical to helical morphology

Let's do the twist: Tripodal squaraines self-assemble from acetonitrile to form hollow spheres, the complexation of which with Ca<SUP>2+</SUP> or Mg<SUP>2+</SUP> results in extended networks. An analogous chiral dye exhibits a bisignate CD couplet and a helical morphology upon Ca<SUP>2+</SUP> binding (see figure). Thus, the molecular chirality of a functional dye is expressed through specific cation binding and manifested in the form of supramolecular helicity

Level Identification of Brain MR Images using Histogram of a LBP variant

Axial brain slices containing similar anatomical structures are retrieved using features derived from the histogram of Local binary pattern (LBP). A rotation invariant description of texture in terms of texture patterns and their strength is obtained with the incorporation of local variance to the LBP, called Modified LBP (MOD-LBP). In this paper, we compare Histogram based Features of LBP (HF/LBP), against Histogram based Features of MOD-LBP (HF/MOD-LBP) in retrieving similar axial brain images. We show that replacing local histogram with a local distance transform based similarity metric further improves the performance of MOD-LBP based image retrievalCochin University of Science and Technology2012 IEEE International Conference on Computational Intelligence and Computing Researc

Content Based Image Retrieval of Brain MR Images across Different Classes

Magnetic Resonance Imaging play a vital role in the decision-diagnosis process of brain MR images. For an accurate diagnosis of brain related problems, the experts mostly compares both T1 and T2 weighted images as the information presented in these two images are complementary. In this paper, rotational and translational invariant form of Local binary Pattern (LBP) with additional gray scale information is used to retrieve similar slices of T1 weighted images from T2 weighted images or vice versa. The incorporation of additional gray scale information on LBP can extract more local texture information. The accuracy of retrieval can be improved by extracting moment features of LBP and reweighting the features based on users’ feedback. Here retrieval is done in a single subject scenario where similar images of a particular subject at a particular level are retrieved, and multiple subjects scenario where relevant images at a particular level across the subjects are retrievedCochin University of Science and TechnologyInternational Journal of Electrical, Robotics, Electronics and Communications Engineering Vol:7 No:8, 201

The influence of crystal packing on the solid state fluorescence behavior of alkyloxy substituted phenyleneethynylenes

The study reports the solid state photophysical properties of a series of alkyloxy-substituted oligo(phenyleneethynylene)s, methoxy to hexyloxy, supported by a detailed analysis of molecular packing obtained from single crystal X-ray diffraction data. While the emission peaks are highly red shifted (by as much as 114 nm) in the solid state, all molecules exhibit similar absorption and emission in dilute solutions. The red shift is maximum in ethoxy and minimum in methoxy, while other crystalline films exhibit intermediate values. In the crystal structures, the spacing between the molecular pairs forming the J-aggregates is varied between 3.48 to 4.65 &#197;, with no systematic dependence on the chain length. The red shifted emission maximum is found to vary linearly with the spacing between the interacting molecules in the J-aggregate. Thus, the emission in the solid state is determined by the extent of dipolar coupling between the molecules, the alkyl chain length influencing the properties only indirectly