Ovarian cancer histology-specific incidence trends in Canada 1969–1993: age-period-cohort analyses

This study examined histology-specific incidence trends of ovarian cancer in Canada, 1969–1993. The impact of age, period and cohort effects on these trends were studied by means of age-period-cohort analysis. Age-standardized incidence rates of serous, endometrioid, clear cell and germ cell tumours increased significantly and the rates of sex cord-stromal and other classified epithelial ovarian tumours decreased considerably. The rates of mucinous and NOS/unclassified tumours remained unchanged. Cohort effect has a major impact on incidence trends of serous, endometrioid, germ cell, sex cord-stromal and other classified epithelial ovarian tumours but no meaningful impact on trends of mucinous, clear cell, or NOS/unclassified ovarian tumours. Various cohort patterns by histology subtypes were observed: the risk of developing serious tumours increased markedly among birth cohorts of 1895–1930, stabilized thereafter and decreased among young cohorts of 1950–1960; the risk of germ cell tumours increased significantly among young cohorts of 1965–1980; and the risk of sex cord-stromal tumours dropped constantly among cohorts 1910–1950. Various period patterns by histology subtypes observed in this study suggested changes in histology classification criteria over the period. Further studies need to consider the various etiologies and the classification criteria changes according to histology subtypes. © 1999 Cancer Research Campaig

Living at Gele Scheikunde: How to redevelop former campus buildings by integrating social & ecological values?

This research looks at Gele Scheikunde - a TU Delft chemistry department building constructed in 1945. The complex served for educational purposes until 2012 and then was sold by TU for redevelopment.The ambition of the city of Delft is to increase the housing stock, furthermore, the number of TU campus users has grown significantly in recent years. This brings up a dilemma between densification and quality of life. For these reasons, abandoned or non-used buildings like TU faculty building Gele Scheikunde is envisioned for housing purpose. According to the official regulations and the Commission for Environmental Impact Assessment (MER), there is great potential in this university area to develop an innovative sustainable neighbourhood. Thus, the question that arises is: How to redevelop the former campus buildings?The goal is to research on how to cope with abandoned campus buildings by including social and ecological values into the transformation and re-adaption design. The approach for the research was to involve stakeholders in the co-creation process. This co-creation process was facilitated through the Minecraft workshop. During the workshop, not only experts (e.g. architects, designers, planners) but also external parties (e.g. neighbours, users, ecologists), decided over the built environment. However, a co-creation approach is not limited to one method. There are various ways to involve stakeholders: interviews, surveys, questionnaires and workshops, with or without heritage games. For this research, a combination of the above was chosen: interviews, surveys and a gaming workshop with Minecraft.This approach provided information on what is valued in the case study, why it is valued, what should be kept and what can be demolished. Besides all stakeholders shared their opinion on what would be the best “new program”.Gele ScheikundeHeritage4allArchitecture, Urbanism and Building Sciences | Heritage & Architectur