42 research outputs found
Tumores cerebrales de origen astrocítico: caracterización clínica y epidemiológica
A retrospective, descriptive and transversal study was carried out in the hospital ”Arnaldo Milian Castro” in the period from August 1998 to August 2005 in patients histologically diagnosed with malignant brain tumors of astrocytic lineage. In the process of this study was made a characterization of patients that suffered from malignant brain tumors of astrocytic lineage. Some parametrs were taken into account such as: age, sex, race, clinical manifestations, diagnostic means, more frecuent localization and histologic grade. Using these variables and the percent method was found that these tumors frecuently appear after fifties, in persons of male sex and white race. Endocraneal hypertensión, headache and neurological localization symptoms were most frecuent. The most useful means for the diagnosis proved to be the computer axial tomography. The basic localization of tumor was detected in the brain hemispheres, and was found also a malignant tumors' predominance.Se realizó un estudio retrospectivo, descriptivo y transversal en el Hospital Provincial Universitario “Arnaldo Milián Castro” en el período de agosto de 1998 a agosto de 2005, con 104 pacientes a los que se les diagnosticó histológicamente un tumor cerebral maligno de la serie astrocítica. Nos propusimos caracterizar a los pacientes que padecieron tumores cerebrales de la serie astrocítica, se tuvieron en cuenta: edad, sexo, raza, manisfestaciones clínicas, medios diagnósticos, localización más frecuente y grado histológico. Con estas variables y el empleo del método de por ciento encontramos que estos tumores aparecieron frecuentemente después de los 50 años, en el sexo masculino y en la raza blanca. La cefalea, y los signos y síntomas de focalización neurológica y de hipertensión endocraneana son los más frecuentes; la tomografía axial computadorizada es un medio útil para el diagnóstico; su ubicación fundamental fue en los hemisferios cerebrales y predominaron los de alto grado de malignidad
Caracterización de la epilepsia de inicio en el adulto mayor
An observational descriptive cross-sectional study was performed where the methods of descriptive statistics were used. The aim was to characterize the onset epilepsy in the elderly in clinical-surgical hospital in Villa Clara province. In the study predominant age was a group of 75-79 years, particularly males and white, simple partial secondarily generalized seizures were the most frequent, focal paroxysms were the most important finding in the electroencephalogram (EEG), and the symptomatic etiology prevailed over the cryptogenic etiology. Cerebrovascular disease was the main cause identified.Se realizó un estudio observacional de tipo descriptivo transversal en el que se emplearon los métodos de la estadística descriptiva. El objetivo fue caracterizar la epilepsia de inicio en el adulto mayor en el Hospital Clínico Quirúrgico “Arnaldo Milián Castro” de la Cuidad de Santa Clara, Provincia de Villa Clara. En el estudio predominó el grupo de edad de 75-79 años, se destacaron el sexo masculino y la raza blanca, las crisis epilépticas parciales simples secundariamente generalizadas fueron las más frecuentes, los paroxismos focales constituyeron el hallazgo más relevante en el electroencefalograma, la etiología sintomática prevaleció sobre la criptogénica y la enfermedad cerebrovascular constituyó la principal causa identificada
Seminario de Economía Mexicana
Serie de ponencias referentes al Seminario de Economía Mexicana. Memorias del Seminario de Economía Mexicana de 199
Temas Socio-Jurídicos. Volumen 30 No. 62 Junio 2012
La Revista Temas Socio Jurídicos es una publicación seriada del Centro de Investigaciones Socio Jurídicas, dependencia adscrita a la Facultad de Derecho de la Universidad Autónoma de Bucaramanga, que se dirige principalmente a Abogados, profesionales de las ciencias sociales y humanas, a estudiantes de derecho y de ciencias sociales y humanas.The Socio Legal Issues Magazine is a serial publication of the Socio Legal Research Center, a dependency attached to the Faculty of Law of the Autonomous University of Bucaramanga, which is aimed mainly at Lawyers, professionals in the social and human sciences, law students and social and human sciences
Women in (Dis)placement: The Field of Studies on Migrations, Social Remittances, Care and Gender in Chile
This article presents current perspectives on the gender approach to the study of migration in Chile between 1990 and 2018, contextualizing it in light of international debates in the social sciences. We will discuss how the feminization and the growth of Latin American migrations have given rise to a prolific field of research, as exemplified by studies conducted in central and northern Chile. We will show how the concepts of social remittances and caregiving permeate the Chilean debate on migrant women. We conclude with reflections on topics and perspectives to be incorporated into the Chilean research agenda on gender and migration.Se presenta un estado del arte sobre el enfoque de género en los estudios de la migración en Chile entre 1990 y 2018, contextualizándolo a la luz de debates internacionales de las ciencias sociales. Abordaremos cómo la feminización y el incremento de las migraciones latinoamericanas inauguran un prolijo campo de investigaciones, articulado a través de estudios desarrollados en el centro y en el norte de Chile. Señalaremos cómo los conceptos de remesas sociales y cuidados permean el debate chileno sobre las mujeres migrantes. Finalizamos con reflexiones sobre temas y perspectivas a ser incorporados en la agenda chilena de investigaciones sobre género y migración.The authors would like to thank the Chilean National Commission for Scientific and Technological Research (CONICYT) for funding the study that led to this article through Fondecyt Regular Project number 1160683: “Ser Mujer Mayor en Santiago. Organización social de los cuidados, feminización del envejecimiento y desigualdades acumuladas” (“Being an older woman in Santiago. Social organization of care, feminization of ageing and accumulated inequalities”), led by Herminia Gonzálvez Torralbo and Fondecyt Regular Project number 1190056: “The Boundaries of Gender Violence: Migrant Women’s Experiences in South American Border Territories” led by Menara Lube Guizardi
Repositioning of the global epicentre of non-optimal cholesterol
High blood cholesterol is typically considered a feature of wealthy western countries(1,2). However, dietary and behavioural determinants of blood cholesterol are changing rapidly throughout the world(3) and countries are using lipid-lowering medications at varying rates. These changes can have distinct effects on the levels of high-density lipoprotein (HDL) cholesterol and non-HDL cholesterol, which have different effects on human health(4,5). However, the trends of HDL and non-HDL cholesterol levels over time have not been previously reported in a global analysis. Here we pooled 1,127 population-based studies that measured blood lipids in 102.6 million individuals aged 18 years and older to estimate trends from 1980 to 2018 in mean total, non-HDL and HDL cholesterol levels for 200 countries. Globally, there was little change in total or non-HDL cholesterol from 1980 to 2018. This was a net effect of increases in low- and middle-income countries, especially in east and southeast Asia, and decreases in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe. As a result, countries with the highest level of non-HDL cholesterol-which is a marker of cardiovascular riskchanged from those in western Europe such as Belgium, Finland, Greenland, Iceland, Norway, Sweden, Switzerland and Malta in 1980 to those in Asia and the Pacific, such as Tokelau, Malaysia, The Philippines and Thailand. In 2017, high non-HDL cholesterol was responsible for an estimated 3.9 million (95% credible interval 3.7 million-4.2 million) worldwide deaths, half of which occurred in east, southeast and south Asia. The global repositioning of lipid-related risk, with non-optimal cholesterol shifting from a distinct feature of high-income countries in northwestern Europe, north America and Australasia to one that affects countries in east and southeast Asia and Oceania should motivate the use of population-based policies and personal interventions to improve nutrition and enhance access to treatment throughout the world.Peer reviewe
A consensus protocol for functional connectivity analysis in the rat brain
Task-free functional connectivity in animal models provides an experimental framework to examine connectivity phenomena under controlled conditions and allows for comparisons with data modalities collected under invasive or terminal procedures. Currently, animal acquisitions are performed with varying protocols and analyses that hamper result comparison and integration. Here we introduce StandardRat, a consensus rat functional magnetic resonance imaging acquisition protocol tested across 20 centers. To develop this protocol with optimized acquisition and processing parameters, we initially aggregated 65 functional imaging datasets acquired from rats across 46 centers. We developed a reproducible pipeline for analyzing rat data acquired with diverse protocols and determined experimental and processing parameters associated with the robust detection of functional connectivity across centers. We show that the standardized protocol enhances biologically plausible functional connectivity patterns relative to previous acquisitions. The protocol and processing pipeline described here is openly shared with the neuroimaging community to promote interoperability and cooperation toward tackling the most important challenges in neuroscience
Genome-wide association study of germline variants and breast cancer-specific mortality
BACKGROUND: We examined the associations between germline variants and breast cancer mortality using a large meta-analysis
of women of European ancestry.
METHODS: Meta-analyses included summary estimates based on Cox models of twelve datasets using ~10
Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight NCD Risk Factor Collaboration (NCD-RisC)
From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of underweight, obesity, and severe obesity in different regions using data from 2896 population-based studies with 187 million participants. Changes in the prevalence of underweight and total obesity, and to a lesser extent severe obesity, are largely driven by shifts in the distribution of BMI, with smaller contributions from changes in the shape of the distribution. In East and Southeast Asia and sub-Saharan Africa, the underweight tail of the BMI distribution was left behind as the distribution shifted. There is a need for policies that address all forms of malnutrition by making healthy foods accessible and affordable, while restricting unhealthy foods through fiscal and regulatory restrictions