Matching of Descriptive Labels to Glossary Descriptions

Semantic text similarity plays an important role in software engineering tasks in which engineers are requested to clarify the semantics of descriptive labels (e.g., business terms, table column names) that are often consists of too short or too generic words and appears in their IT systems. We formulate this type of problem as a task of matching descriptive labels to glossary descriptions. We then propose a framework to leverage an existing semantic text similarity measurement (STS) and augment it using semantic label enrichment and set-based collective contextualization where the former is a method to retrieve sentences relevant to a given label and the latter is a method to compute similarity between two contexts each of which is derived from a set of texts (e.g., column names in the same table). We performed an experiment on two datasets derived from publicly available data sources. The result indicated that the proposed methods helped the underlying STS correctly match more descriptive labels with the descriptions

Varicella-zoster virus ORF 58 gene is dispensable for viral replication in cell culture

<p>Abstract</p> <p>Background</p> <p>Open reading frame 58 (ORF58) of varicella-zoster virus (VZV) lies at the 3'end of the Unique long (U_L) region and its functional is unknown. In order to clarify whether ORF58 is essential for the growth of VZV, we constructed a deletion mutant of ORF58 (pOka-BACΔ58) from the Oka parental genome cloned into a bacterial artificial chromosome (pOka-BAC).</p> <p>Results</p> <p>The ORF58-deleted virus (rpOkaΔ58) was reconstituted from the pOka-BACΔ58 genome in MRC-5 cells, indicating that the ORF58 gene is non-essential for virus growth. Comparison of the growth rate of rpOkaΔ58 and recombinant wild-type virus by assessing plaque sizes revealed no significant differences between them both in MRC-5 cells and malignant melanoma cells.</p> <p>Conclusion</p> <p>This study shows that the ORF58 gene is dispensable for viral replication and does not affect the virus' ability to form plaques <it>in vitro</it>.</p