弾性義歯裏装材の動的粘弾性が義歯の負担圧および咀嚼に及ぼす影響に関する研究

広島大学(Hiroshima University)博士(歯学)Dentistrydoctora

Biomechanical Study of Cervical Posterior Decompression

Study Design Biomechanical study. Purpose We examined the dynamic characteristics of different operative procedures using three-dimensional finite-element models. Overview of Literature Cervical laminoplasty is often selected for patients requiring multilevel spinal decompression. Many laminoplasty techniques have been developed and are continually being improved. Methods Images were extracted for the two intervertebral joints between C3 and C5 in domestic rabbits. The following models were created: preoperative, laminectomy, Z-plasty, open door laminoplasty, French open door laminoplasty, en-bloc laminoplasty, and double-door laminoplasty. The loads required for sagittal rotation of 2.5°, 5°, and 7.5° were measured in vitro and respectively placed at the bottom of the C5 model. Displacement of the plate in the X, Y, and Z coordinates was measured and the rotational angles of the plate were determined. Results The sagittal rotation angle was greater in the laminectomy model than in the preoperative model, but was almost the same in the preoperative and Z-plasty models. Compared with the preoperative model, sagittal rotation angles were smaller in the French open door, open door, en-bloc, and double-door laminoplasty models. Conclusions Laminectomy and various types of laminoplasty are associated with different mechanical features, such as stability and mobility, allowing for selection of the most appropriate surgical procedure for each case

B Chromosomes Have a Functional Effect on Female Sex Determination in Lake Victoria Cichlid Fishes

The endemic cichlid fishes in Lake Victoria are a model system for speciation through adaptive radiation. Although the evolution of the sex-determination system may also play a role in speciation, little is known about the sex-determination system of Lake Victoria cichlids. To understand the evolution of the sex-determination system in these fish, we performed cytogenetic analysis in 11 cichlid species from Lake Victoria. B chromosomes, which are present in addition to standard chromosomes, were found at a high prevalence rate (85%) in these cichlids. In one species, B chromosomes were female-specific. Cross-breeding using females with and without the B chromosomes demonstrated that the presence of the B chromosomes leads to a female-biased sex ratio in this species. Although B chromosomes were believed to be selfish genetic elements with little effect on phenotype and to lack protein-coding genes, the present study provides evidence that B chromosomes have a functional effect on female sex determination. FISH analysis using a BAC clone containing B chromosome DNA suggested that the B chromosomes are derived from sex chromosomes. Determination of the nucleotide sequences of this clone (104.5 kb) revealed the presence of several protein-coding genes in the B chromosome, suggesting that B chromosomes have the potential to contain functional genes. Because some sex chromosomes in amphibians and arthropods are thought to be derived from B chromosomes, the B chromosomes in Lake Victoria cichlids may represent an evolutionary transition toward the generation of sex chromosomes

Education of Health Communication in Postgraduate Dental Clinical Training Course : The Result of Informed Consent in OSCE

本論文の要旨は平成13年12月の第85回広島大学歯学会例会において発表した

Dynamic viscoelastic properties and the age changes of long-term soft denture liners

The dynamic viscoelastic properties of long-term soft denture liners were measured over a wide range of frequencies using a dynamic viscoelastometer based on a non-resonance-forced vibration principle. Changes in properties over a 3 yr period have also been monitored. One acrylic material, one fluoroelastomer, one heat cured silicone and one self-curing addition silicone were used. Complex dynamic tensile modulus (E*), tensile storage modulus (E′), tensile loss modulus (E″) and loss tangent (tan δ) were determined over the frequency range from 0.01 to 100 Hz on administration of a 0.27(null)train at 37°C. The dynamic viscoelasticity of the acrylic and fluoroelastomer products was more sensitive to changes in frequency than that of silicone products. The acrylic material and fluoroelastomer exhibited viscoelastic behaviour whilst silicones exhibited elastic behaviour. The silicone products remained unchanged after soaking for 3 yr whilst the acrylic and fluoroelastomer products underwent significant change

Diagnosis and Characters of Non-Specific Low Back Pain in Japan: The Yamaguchi Low Back Pain Study.

Cross sectional data from the Yamaguchi low back pain study conducted in Yamaguchi prefecture, Japan, was used for this analysis.A total of 320 patients were recruited from walk-in orthopedic clinics in Yamaguchi Prefecture, Japan. Patients visited the clinics primarily for low back pain (LBP) and sought treatment between April and May 2015. A self-questionnaire was completed by patients, while radiographic testing and neurological and physical examination was performed by the orthopedist in each hospital. The cause and characters of LBP was determined following examination of the data, regional anesthesia and block injection.'Specific LBP' was diagnosed in 250 (78%) patients and non-diagnosable, 'non-specific LBP' in 70 (22%) patients. The VAS scores of patients were: LBP, 5.8±0.18; leg pain, 2.9±0.18 and the intensity of leg numbness was 1.9±0.16. Item scores for SF-8 were: general health, 46.6±0.40; physical function, 43.5±0.51; physical limitations, 42.8±0.53; body pain, 42.1±0.52; vitality, 48.4±0.37; social function, 46.9±0.53; emotional problems, 48.9±0.43; mental health, 46.9±0.43.The incidence of non-specific LBP in Japan was lower than previous reports from western countries, presumably because of variation in the diagnosis of LBP between different health care systems. In Japan, 78% of cases were classified as 'specific LBP' by orthopedists. Identification of the definitive cause of LBP should help to improve the quality of LBP treatment