12 research outputs found
Identification of three human pseudogenes for subunit Vlb of cytochrome c oxidase: a molecular record of gene evolution
No full textThree pseudogenes for the nuclear-encoded subunit VIb of cytochrome c oxidase (COX) were isolated by screening a human genomic library with cloned human cDNA coding for COX subunit VIb. The nucleotide sequences of the pseudogenes, designated PSI-COX6b-1, PSI-COX6b-2 and PSI-COX6b-3, were determined. Pseudogene PSI-COX6b-1 bears all the hallmarks of a processed pseudogene and diverged from the parental gene after the divergence of man and cow. Alu repetitive elements were integrated into the structural sequences of the other two pseudogenes. Comparison with the human and bovine cDNA sequences encoding COX subunit VIb suggests that PSI-COX6b-2 and PSI-COX6b-3 were formed earlier in evolution than PSI-COX6b-1. Genomic Southern analysis indicated that a few more pseudogenes for COX subunit VIb are likely to be present in the human genome. Identical nt differences with respect to the human cDNA sequence in the pseudogenes provide some clues on the evolution of the ancestral gene coding for COX subunit VIb
Expression of nodulin genes during nodule development from effective and ineffective root nodules
No full textA novel frameshift mutation of the mtDNA COIII gene leads to impaired assembly of cytochrome c oxidase in a patient affected by leigh-like syndrome
No full textA novel frameshift mutation of the mtDNA COIII gene leads to impaired assembly of cytochrome c oxidase in a patient affected by leigh-like syndrome
No full textDéplétion de l'ADN mitochondrial et mutations du gène de la déoxyguanosine kinase
No full textNational audienc
BMI and Waist Circumference Have Positive Correlation With Mitochondrial DNA Copy Number in Young Adult Male
No full textExpression of mitochondrial transcripts in gastric MGC803 cell line subjected by hypoxia
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Rearrangements of Human Mitochondrial DNA (mtDNA): New Insights into the Regulation of mtDNA Copy Number and Gene Expression
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