4 research outputs found

    Operational activities of Security Service against „Tygodnik Powszechny” in 1957–1965 (chosen issues)

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    „Tygodnik Powszechny” – a Catholic socio-cultural magazine issued in Cracow gathered catholic opposition against communist authorities. The policy of so called „mild opposition” accepted by the magazine allowed for publishing a weekly magazine, the programme of which differed from requirements of the state authorities. The magazine was tolerated by the communists, who used the fact of its existence as a proof for the alleged pluralism and democratic rule in Poland. For all the period of its existence, from the first issue in 1945 till until the fall of the communist regime, the communist political police was interested in the editorial staff of the magazine. In 1957–1965 Security Service was leading a group operational action with a code names „Pióro” and later „Pismak” against „leadership active” of the editorial staff. The information was gathered from telephone bugs installed in the editorial office, room bugging (code name „Gawron”) operating since 1963 and personal sources of information, the most important of whom were secret agents „Ares” and „Erski”. The operational methods used allowed Security Service offi cers to be familiar with moods among members of the editorial staff, comments about current events and some of the plans of the staff. Moreover, Security Service was well informed of the fi nancial situation of the magazine and was able to name all the magazine co-operators, also those who wanted to be anonymous and used pseudonyms. Among the defeats of the Security Service in the period described one can name the fact that its offi cers were not able to enrol for co-operation no-one from the main editors of the magazine. Another issue was that the Security Service did not know about plans of Jerzy Turowicz to sign so called „Letter of the 34” and was not able to prevent it

    Wielka moc w małej cząsteczce : właściwości i zastosowania bisfosfonianów

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    Great power in a small molecule : properties and applications of bisphosphonate

    Familial hypertrophic cardiomyopathy. Insertion-deletion polymorphism of angiotensin-converting enzyme and angiotensin II receptor

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    Background: Hypertrophic cardiomyopathy (HCM) is a genetic-based disease. Several gene mutations leading to HCM development have been described.Aim: Detailed examination of phenotype and genotype of a family with HCM.Methods: Clinical and genetic examinations were performed in a family with HCM, in which 3 sick persons with different disease phenotype were found.Results: In all sick persons the same molecular substitution G->A (AGG->AAG) was noticed. It led to substitution Arg780-Lys in exon 21 β-myosin heavy chain gene, which was responsible for the development of the disease. Insertion- deletion polymorphism analysis in ACE gene revealed D/D (deletion/deletion) genotype in proband and D/I (deletion/ insertion) phenotype in his mother and sister, who were heterozygous. Polymorphism A1166C analysis in AT1 gene revealed the presence of genotype A/A in proband and A/C in his mother and sister. In proband and his sister a very similar phenotype was observed, whereas they had different polymorphism for ACE gene and angiotensin 1 receptor gene. In sick proband's mother, who had phenotype different to her children, the same polymorphism as in his daughter was noticed.Conclusions: In the described family with HCM, different phenotype and polymorphism of ACE and AT1 genes were found
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