454 research outputs found
Dynamic service composition for telecommunication services and its challenges
As communication networks have evolved towards IP (Internet Protocol) networks, telecommunication operators has expanded its reach to internet multimedia web content services while operating circuit-switch networks in parallel. With the adoption of SOA (Service Oriented Architecture) that enables service capability interfaces to be published and integrated with other service capabilities into new composite service, service composition allows telecommunication providers to accelerate more new services provisioning. From the perspective of telecommunication providers to deliver integrated composite service from different providers and different network protocols, this paper is aimed to present the current service composition based on middleware approaches; discuss the requirements of meeting the challenges; and compare the approaches
Familial homocystinuria
Two cases of siblings diagnosed as cases of familial homocystinuria are reported. Both the cases have classical presentation of familial homocystinuria including history of dislocation of lens of the right eye. Brother had history of psychomotor retardation while sister had a significant history of deep vein thrombosis. Levels of plasma homocysteine were elevated and urinary homocysteine was positive in both the cases
Focus prosody in Brahvi and Balochi
Previous research has shown that post-focus compression (PFC) - the reduction of F0 and intensity after a focused word, is present in some languages but absent in many others. It has been hypothesized that the cross-linguistic distribution of PFC parallels that of the Nostratic macro-family. The present study is a test of this Nostratic-origin hypothesis through a comparison of focus prosody in Brahvi, a Dravidian language, and Balochi, an Indo-Iranian language, both alleged members of the Nostratic macro-family. Twenty native speakers from each language produced declarative sentences with different focus conditions. Acoustic analysis showed that, in both languages, post-focus F0 peaks are significantly lower than those in baseline neutral-focus sentences. But post-focus lowering of F0 and intensity is greater in Balochi than in Brahvi. These results offer evidence that at least one of the Dravidian languages has PFC, which is consistent with the Nostratic-origin hypothesis. The weaker form of PFC in Brahvi, however, suggests that factors that may weaken PFC in a language need to be investigated, and other Dravidian languages also need to be studied for the presence of PFC
A Case Study of the Ritual Space Construction of the Chinese Festival Series Program
TV festival gala is one important form of ritual communication of traditional Chinese festivals. The Chinese Festival Series Program innovate the ritual construction path of the program while maintaining the sense of ritual of the traditional festival galas, making the Chinese Festival Series Program a representative work of Chinese festival galas in recent years. This study aims to explore the ritual space construction of the Chinese Festival Series Program. It adopted the case study approach by taking Chinese Festival Series Program as the research object, and analyzed the text of the programs mainly from the physical space, media space, narrative space and the associated space of history and reality. The analysis results demonstrated that breaking the single physical space and building diverse scenes can make the narrative more hierarchical, and allow the audiences to experience a more realistic program space. The addition of new technology also brings richness to the narrative space. The convenient interactivity of the new media platform creates an exclusive media interaction space for the audiences. Through the ritual space construction, the Chinese Festival Series Program associate the past space with the present space, allowing the audiences to develop memory-related activities in the ritual space
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Narratives on education for sustainable development in Malaysian universities
Higher education institutions are powerful forces in producing the human capital necessary to drive sustainable development. To support global aspirations to improve our planet, higher education institutions worldwide have been integrating the education for sustainable development agenda within the curriculum of a wide range of disciplines. This study aims to describe how Malaysian public universities have been implementing education for sustainable development. By adopting a qualitative research approach, this study gathered data through in-depth interviews and four focus group discussions with 16 sustainability experts from five public universities in Malaysia, renowned for their education provision and research in the field of sustainable development. Thematic analyses of the data reveal four prevailing approaches to implementing education for sustainable development at Malaysian higher education institutions. They are the organisational adoption approach, the competitive approach, the continuity approach, and the transformative approach. This study also projects the idea that the implementation of education for sustainable development (ESD) requires solid support from the institutions’ senior management to prioritise it in their managerial agenda
Comparison of Correction Techniques for the Spill in Effect in Emission Tomography
In positron emission tomography (PET) imaging, accurate clinical assessment is often affected by the partial volume effect (PVE) leading to overestimation (spill-in) or underestimation (spill-out) of activity in various small regions. The spill-in correction, in particular, can be very challenging when the target region is close to a hot background region. Therefore, this study evaluates and compares the performance of various recently developed spill-in correction techniques, namely: background correction (BC), local projection (LP), and hybrid kernelized (HKEM) methods. We used a simulated digital phantom and 18F-NaF PET data of three patients with abdominal aortic aneurysms (AAA) acquired with Siemens Biograph mMRTM and mCTTM scanners respectively. Region of Interest (ROI) analysis was performed and the extracted SUVmean, SUVmax and target-to-background ratio (TBR) scores were compared. Results showed substantial spill-in effects from hot regions to targeted regions, which are more prominent in small structures. The phantom experiment demonstrated the feasibility of spill-in correction with all methods. For the patient data, large differences in SUVmean, SUVmax and TBRmax scores were observed between the ROIs drawn over the entire aneurysm and ROIs excluding some regions close to the bone. Overall, BC yielded the best performance in spill-in correction in both phantom and patient studies
SPRTN protease-cleaved MRE11 decreases DNA repair and radiosensitises cancer cells
Funding Information: This work was funded by CRUK Programme Grant C5255/A23755. Acknowledgements Mass spectrometry analysis was performed in the MS laboratory at the Target discovery institute—NDM (Oxford) led by Benedikt M. Kessler. We thank Drs. Eva McGrowder and Blaz Groselj for processing of primary bladder tumour samples to produce cell-free extracts. Data availability The LC-MS/MS proteomics data have been deposited to the ProteomeXchange Consortium via the PRIDE48 partner repository with the dataset identifier PXD017964 and 10.6019/PXD017964.Peer reviewedPublisher PD
Modus Operandi Extraction in Police Report
Background: This paper analyzes the modus operandi extraction in Malay language using information retrieval technique. The similarity of modus operandi will be measured according to the cosine of the angle between query and document vectors. Our research focuses on phrase identification to find out the rules of forming modus operandi from free-text of police reports. Modus operandi is the most important aspect in a police investigation. The valuable data that relevant to the user's information needed in free-text report is a challenge and difficult to be detected or tracked by the police. It would be better if modus operandi from text reports such as location of crime and crime behavior could be identified automatically. This paper also shows that modus operandi extraction can improve the performance of similarity measurement using precision, recall and F-measures. It evaluates the accuracy of modus operandi extraction on each report from ten different police reports. The best F-measure is 0.960 with recall and precision at 1.0 and 0.933 respectively for retrieval performance of modus operandi extraction
Synergistic Antibacterial Effects of Metallic Nanoparticle Combinations
© The Author(s) 2019.Metallic nanoparticles have unique antimicrobial properties that make them suitable for use within medical and pharmaceutical devices to prevent the spread of infection in healthcare. The use of nanoparticles in healthcare is on the increase with silver being used in many devices. However, not all metallic nanoparticles can target and kill all disease-causing bacteria. To overcome this, a combination of several different metallic nanoparticles were used in this study to compare effects of multiple metallic nanoparticles when in combination than when used singly, as single elemental nanoparticles (SENPs), against two common hospital acquired pathogens (Staphylococcus aureus and Pseudomonas. aeruginosa). Flow cytometry LIVE/DEAD assay was used to determine rates of cell death within a bacterial population when exposed to the nanoparticles. Results were analysed using linear models to compare effectiveness of three different metallic nanoparticles, tungsten carbide (WC), silver (Ag) and copper (Cu), in combination and separately. Results show that when the nanoparticles are placed in combination (NPCs), antimicrobial effects significantly increase than when compared with SENPs (P < 0.01). This study demonstrates that certain metallic nanoparticles can be used in combination to improve the antimicrobial efficiency in destroying morphologically distinct pathogens within the healthcare and pharmaceutical industry.Peer reviewe
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