Realising Value: Study-Related Support-Seeking Experiences

The idea of ‘exchange’ in Service Dominant Logic’s (S-D logic) Foundational Premise (FP) 1 (service is ‘exchanged’ for service) has retained the residual transactional concept from Goods Dominant Logic (G-D logic) as the basis of understanding of service in S-D logic. This has limited the processual understanding in S-D logic; in particular, the need to understand value as a process rather than an output. This study meets that need in presenting a holistic understanding of the individual’s valuing process for S-D logic. An interdisciplinary search of literature beyond the discipline of marketing on the term ‘valuing’ was conducted in the fields of psychology, education, and systems thinking. This study investigates how students with disabilities realise value through study-related support-seeking experiences. Sixteen students with disabilities, who were enrolled in higher educational services in New Zealand, participated in this study. A phenomenographic approach was applied to understand the variations in ways that students with disabilities experienced and understood the support-seeking phenomenon. The variations and similarities in meanings were abstracted as categories of description. Four categories of description of Knowing, Understanding, Judging, and Acting represented participants’ conceptions of experiencing the support-seeking phenomenon. Each category of description outlined both the variations in meanings and the structural aspects of experiencing the phenomenon. The four categories of description were logically displayed in an outcome space - a hermeneutical spiral - to portray the different ways of experiencing the support-seeking phenomenon. The hermeneutic spiral provides a holistic understanding of the valuing process for S-D logic’s view of service as a process. Hence, value is not a perceptual state at an endpoint of time, rather it is a here-and-now snapshot ‘taking stock’ in a dynamic process. The second contribution this study makes to S-D logic relates to the processual understanding of value. In the process of valuing, the participants were experiencing and understanding the support-seeking phenomenon in relation to their mental acts, or structural awareness, at a moment of time. Thus, participants appreciate, and act upon their thoughts. This builds on the S-D logic’s Foundational Premise (FP) 10 that the beneficiary always uniquely and phenomenologically determines value. Specifically, the second contribution of this research relates directly to the insights revealed by the phenomenography method into variations in participants’ experiences of support-seeking. The research provides sound empirical support for valuing as a dynamic process, which extends the FP10 notion of value as a static valuation at a particular point in time. Along with the S-D logic contributions, this study contributes phenomenography as a research method that is little known in marketing. This method has the potential to understand the variations of individuals’ realities as experienced. The practical implication of this study adds to knowledge of support-seeking behaviour as an avenue for businesses to engage in people’s appreciation and be of service to them

Evaluating cell-mimicking giant unilamellar vesicles as simplified biological models using single molecule methods

One of the main drivers within the field of bottom-up synthetic biology is to develop artificial chemical machines, perhaps even living systems, that have programmable functionality. Bottom-up methods take an engineering approach to biology, with multiple downstream applications. Such applications that require very specific quantities of product e.g., antibodies, drug, or vaccines, necessitate the design of vesicles with total and precise control of a vesicle’s molecular machinery. There exists a wide range of toolkits to produce and engineer artificial cells with an ever-increasing array of functionality and capability. However, little attention has been given to the quality control of vesicle production; so, to date, there is a paucity of techniques that are able to measure their molecular constituents precisely upon formation and with absolute quantification. The work outlined here presents the development of a microfluidic-based methodology that is able to characterise artificial cells at the single vesicle level with single-molecule resolution. High content fluorescence microscopy was used to assess the properties of Giant unilamellar vesicles (GUVs) and their statistics at the population level. Since this technique is semi-quantitative, the relative concentration of protein across the GUV population was determined however the absolute concentration of protein within each GUV was not. To overcome this, a lab-on-a-chip approach was taken to determine the precise number of biomolecules within each GUV and across the population of GUVs. The pulldown-5 array single-molecule high-throughput (PASH) chip was developed and capable of determining the encapsulation efficiency of protein within GUVs produced by phase transfer of an inverted emulsion. Using this approach, it was possible to determine the variability of the encapsulation efficiency between GUVs across a population as well as between different populations while testing batch-to-batch variation. The encapsulation efficiency measured to be 11.4 ± 6.2% across all tested parameters. This has consequences for the use of GUVs as precise biological models as well as for their development in a variety of biotherapeutic applications. To determine whether GUVs with specific concentrations of biomolecules could be produced by phase transfer, changes in the concentration of the seeding materials and reagents were investigated; while inefficiencies in encapsulation could be overcome, the variation in concentration could not. The results presented in this thesis help to understand the limitation of the phase transfer technique applied to systems biology research. In biological systems, measuring changes in gene expression at the transcriptomic and proteomic level is important. When used to develop simplified models of protein expression, these results indicate that vesicles produced using phase transfer may only be confidently used to produce 10-fold changes in encapsulant protein. It is possible to distinguish different GUV populations with a precision down to a two-fold change in encapsulant protein but with significant population overlap. The understanding of the limitations of encapsulation efficiency provides insight into the potential relevance of such systems for a variety of therapeutic applications such as smart drug delivery.Open Acces

Differential Subordination And Coefficients Problems Of Certain Analytic Functions

Let A be the class of normalized analytic functions f on the unit disk D, in the form f(z) = z+ P1n =2 anzn: A function f in A is univalent if it is a one-to-one mapping. This thesis discussed ¯ve research problems. Lambangkan A sebagai kelas fungsi analisis ternormal pada cakera unit D berbentuk f(z) = z + P1n =2 anzn: Fungsi f dalam A adalah univalen jika fungsi tersebut ialah pemetaan satu ke satu. Tesis ini mengkaji lima masalah penye- lidikan

Bounds for the Second Hankel Determinant of Certain Univalent Functions

The estimates for the second Hankel determinant a_2a_4-a_3^2 of analytic function f(z)=z+a_2 z^2+a_3 z^3+...b for which either zf'(z)/f(z) or 1+zf"(z)/f'(z) is subordinate to certain analytic function are investigated. The estimates for the Hankel determinant for two other classes are also obtained. In particular, the estimates for the Hankel determinant of strongly starlike, parabolic starlike, lemniscate starlike functions are obtained

Convolution and coefficient problems for multivalent functions defined by subordination [QA1].

Dalam Bab 1, kelas-kelas teritlak bak-bintang multivalen, cembung, hampir-cembung dan kuasi-cembung diperkenalkan. Kelas-kelas tersebut memberi kaedah penyatuan untuk pelbagai subkelas yang diketahui sebelum ini. In Chapter 1, the general classes of multi-valent starlike, convex, close-to-convex and quasi-convex functions are introduced. These classes provide a unified treatment to various known subclasses

Support: Can it be a value creation strategy for positive marketing?

In pursuit of improving people's wellbeing and engaging in positive marketing, this paper addresses the application of Vickers' Appreciation System to deepen our understanding of how people comprehend their environment and respond to improve their situation. The paper highlights how companies can collaboratively engage in people's appreciation and support them in fulfilling their needs

Convolution And Coefficient Problems For Multivalent Functions Defined By Subordination

Andaikan C satah kompleks, U = {z E C : Izl < I} cakera unit terbuka dalam C dan H(U) kelas fungsi analisis dalam U. Andaikan juga A kelas fungsi analisis 1 dalam U yang ternormalkan dengan 1(0) = 0 dan 1'(0) = 1. Fungsi 1 E A mempunyai siri Taylor berbentuk 00 l(z) = z + L anzn, (z E U). n=2 Andaikan Ap (p EN) kelas fungsi analisis 1 berbentuk 00 1(z) = zP + L anzn, (z E U) n=p+1 dengan A := AI. Pertimbangkan dua fungsi dalam Ap. Hasil darab Hadamard (atau konvolusi) untuk 1 dan 9 ialah fungsi 1 * 9 berbentuk 00 (J * g)(z) = zP + L anbnzn. n=p+1 Let C be the complex plane and U := {z E C : Izl < I} be the open unit disk in C and H(U) be the class of analytic functions defined in U. Also let A denote the class of all functions I analytic in the open unit disk U := {z E C : Izl < I}, and normalized by 1(0) = 0, and 1'(0) = 1. A function I E A has the Taylor series expansion of the form 00 I(z) = z + ~ (LnZn (z E U). n=2 Let Ap (p EN) be the class of all analytic functions of the form 00 fez) = zP + ~ (LnZn n=p+l with A:= AI. Consider two functions in Ap. The Hadamard product (or convolution) of I and 9 is the function I * 9 defined by 00 (J * g)(z) = zP + ~ anbnzn . "=p+

Synthesis, Characterizations And Release Study Of Ibuprofen-Encapsulated Magnetic Nanocellulose Alginate Hydrogel Beads

Nanokristal selulosa magnetik (m-CNC) telah disintesis daripada nanokristal selulosa (CNC) yang telah diasingkan daripada sekam padi. m-CNC tersebut telah digabungkan kedalam manik hidrogel alginat untuk aplikasi pelepasan dadah ibuprofen Magnetic cellulose nanocrystals (m-CNC) were synthesized from cellulose nanocrystals (CNC) that were isolated from rice husk. m-CNC were incorporated into alginate hydrogel beads for ibuprofen release applicatio