1,838 research outputs found
Relay intercropping soybeans into wheat in non-traditional double-cropping areas of Kansas
Call number: LD2668 .T4 AGRN 1988 D86Master of ScienceAgronom
String Breaking in Quenched QCD
We present preliminary quenched results on a new operator for the
investigation of string-breaking within SU(2)-colour QCD. The ground-state of a
spatially-separated static-light meson-antimeson pair is a combination of a
state with two distinct mesons, expected to dominate for large separations, and
a state where the light-quarks have annihilated, which contributes for short
distances. The crossover between these two regimes provides a measure of the
string-breaking scale length.Comment: LATTICE98(confine), 3 pages, 4 figure
Nutritional and Phytochemical Content of High-Protein Crops
The authors acknowledge support from the Scottish Government’s Rural and Environment Science and Analytical Services Division (RESAS) via their strategic research and partnership programs.Peer reviewedPostprin
Polarized radio emission over the southern Galactic plane at 2.4 GHz
Polarimetric results from the Parkes 2.4-GHz survey of the southern Galactic plane are presented. These take the form of a series of images, detailing the polarized intensity and vector position angles over the survey area. The observations were made using the 64-m Parkes radio telescope, and cover the Galactic plane within the region 238°≤l≤5°, with a latitude range of at least |b|≤5°, with some coverage to b = +7° and b = -8°. The resolution of the images is 10.4 arcmin. The rms noise of the polarized intensity images is 11 mJy beam area-1 (5.3 mK), and the rms variation in the vector position angles is of the order of several dgrees. The images show many polarized structures, over a wide range of intensities and angular sizes. Bright, extended regions of polarized emission (of the order of 5° across) are detected, including the Vela supernova remnant and a large 'cap' structure appearing to the north of Sgr A. A quasi-uniform 'background' component of faint, patchy emission is seen over the length of the survey. This faint component appears to originate over a range of distances, out to greater than 5 kpc, and shows considerable structure in the orientations of the polarization vectors. Several bright H II complexes are seen to exhibit bipolar, depolarizing 'plumes', several degrees in length, which are interpreted as outflows of low-density thermal material (with densities in the range 1-10 cm-3)
Quantum Conductance Oscillations in Metal/Molecule/Metal Switches at Room Temperature
Conductance switching has been reported in many molecular junction devices,
but in most cases has not been convincingly explained. We investigate
conductance switching in Pt/stearic acid monolayer/Ti devices using
pressure-modulated conductance microscopy. For devices with conductance G>>G_Q
or G<<G_Q, where GQ=2e^2/h is the conductance quantum, pressure-induced
conductance peaks <30 nm in diameter are observed, indicating the formation of
nanoscale conducting pathways between the electrodes. For devices with G~ 1- 2
G_Q, in addition to conductance peaks we also observed conductance dips and
oscillations in response to localized pressure. These results can be modeled by
considering interfering electron waves along a quantum conductance channel
between two partially transmitting electrode surfaces. Our findings underscore
the possible use of these devices as atomic-scale switches
Emphysema Is-at the Most-Only a Mild Phenotype in the Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension.
Translational research is essential to develop strategies for the treatment of pulmonary arterial hypertension (PAH) using animal models which reproduce the severity, the progressive nature and resistance to treatment of human PAH, including severe arterial remodeling and progressive right ventricular (RV) failure. We read with interest the letter by Kojonazariov et al. who propose to have found “severe emphysema in the SU5416/Hypoxia (SuHx) rat model of pulmonary hypertension”. The authors report that Wistar-Kyoto rats exposed to the combination of VEGFR2 inhibition by SU5416 and chronic hypoxia had moderately increased RVSP and RV mass compared to normoxic untreated animals. They applied in vivo micro-computed tomography (CT) to demonstrate an increase in lung volume and decreased lung density, an unaltered amount of lung tissue, but an increased air-to-tissue ratio, and claim these findings were confirmed by histological analysis, including mean linear intercept as surrogate of emphysema. Indeed, SU5416 has been previously shown to induce emphysema in normoxia, but this required repetitive SU5416 dosing (3 times weekly over 3 weeks) and occurred more predominantly in rats younger than 4 weeks of age (Norbert Voelkel, personal communication). In addition, emphysema could be negated, at the cost of the development of severe angioproliferative hypertension, by concomitant exposure to hypoxia
Brief Report: Elastin Microfibril Interface 1 and Integrin-Linked Protein Kinase Are Novel Markers of Islet Regenerative Function in Human Multipotent Mesenchymal Stromal Cells
Multipotent mesenchymal stromal cell (MSC) transplantation is proposed as a novel therapy for treating diabetes by promoting the regeneration of damaged islets. The clinical promise of such treatments may be hampered by a high degree of donor-related variability in MSC function and a lack of standards for comparing potency. Here, we set out to identify markers of cultured human MSCs directly associated with islet regenerative function. Stromal cultures from nine separate bone marrow donors were demonstrated to have differing capacities to reduce hyperglycemia in the NOD/SCID streptozotocin-induced diabetic model. Regenerative (R) and non-regenerative (NR) MSC cultures were directly compared using isobaric tags for relative and absolute quantitation (iTRAQ)-based quantitative proteomics. A total of 1,410 proteins were quantified resulting in the identification of 612 upregulated proteins and 275 downregulated proteins by ± 1.2-fold in R-MSC cultures. Elastin microfibril interface 1 (EMILIN-1), integrin-linked protein kinase (ILK), and hepatoma-derived growth factor (HDGF) were differentially expressed in R-MSCs, and Ingenuity Pathway Analyses revealed each candidate as known regulators of integrin signaling. Western blot validation of EMILIN-1, ILK, and HDGF not only showed significantly higher abundance levels in R-MSCs, as compared with NR-MSCs, but also correlated with passage-induced loss of islet-regenerative potential. Generalized estimating equation modeling was applied to examine the association between each marker and blood glucose reduction. Both EMILIN-1 and ILK were significantly associated with blood glucose lowering function in vivo. Our study is the first to identify EMILIN-1 and ILK as prospective markers of islet regenerative function in human MSCs. Stem Cells 2016;34:2249–2255
An ancient river landscape preserved beneath the East Antarctic Ice Sheet
The East Antarctic Ice Sheet (EAIS) has its origins ca. 34 million years ago. Since then, the impact of climate change and past fluctuations in the EAIS margin has been reflected in periods of extensive vs. restricted ice cover and the modification of much of the Antarctic landscape. Resolving processes of landscape evolution is therefore critical for establishing ice sheet history, but it is rare to find unmodified landscapes that record past ice conditions. Here, we discover an extensive relic pre-glacial landscape preserved beneath the central EAIS despite millions of years of ice cover. The landscape was formed by rivers prior to ice sheet build-up but later modified by local glaciation before being dissected by outlet glaciers at the margin of a restricted ice sheet. Preservation of the relic surfaces indicates an absence of significant warm-based ice throughout their history, suggesting any transitions between restricted and expanded ice were rapid
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