New Isocyano and Isothiocyanato Terpene Metabolites from the Tropical Marine Sponge Acanthella cavernosa

Spectroscopic data are reported for 10-isothiocyanato-4-cadinene (4), for 8-hydroxy-isokalihinol F (8) and for two isocyanobifloradiene epoxides, (9) and (10), isolated from Great Barrier Reef specimens of Acanthella cavernosa. (C) 2000 Elsevier Science Ltd. All rights reserved

New chlorinated peptides from the tropical marine sponge Dysidea sp.

Five new chlorinated peptides (5)-(9) have been isolated from a Dysidea sp. and identified by two-dimensional NMR spectroscopy. The absolute stereochemistry of the metabolites was deduced by chemical correlation with S-(-)-4,4,4-trichloro-3-methylbutanoic acid (10) and with an alcohol (11). (C) 2001 Elsevier Science Ltd. All rights reserved