Deep Learning Techniques in Extreme Weather Events: A Review

Extreme weather events pose significant challenges, thereby demanding techniques for accurate analysis and precise forecasting to mitigate its impact. In recent years, deep learning techniques have emerged as a promising approach for weather forecasting and understanding the dynamics of extreme weather events. This review aims to provide a comprehensive overview of the state-of-the-art deep learning in the field. We explore the utilization of deep learning architectures, across various aspects of weather prediction such as thunderstorm, lightning, precipitation, drought, heatwave, cold waves and tropical cyclones. We highlight the potential of deep learning, such as its ability to capture complex patterns and non-linear relationships. Additionally, we discuss the limitations of current approaches and highlight future directions for advancements in the field of meteorology. The insights gained from this systematic review are crucial for the scientific community to make informed decisions and mitigate the impacts of extreme weather events

ANTIDIABETIC AND ANTIDYSLIPIDEMIC ACTIVITY OF ETHYL ACETATE FRACTIONS OF XYLOCARPUS GRANATUM AND XYLOCARPUS MOLLUCCENSIS ON HIGH FRUCTOSE HIGH FAT AND HIGH SUCROSE HIGH FAT FED-LOW DOSED STREPTOZOTOCIN TREATED DIABETIC RATS

Objectives: The present study was carried out to investigate the antidiabetic and antidyslipidemic effect of standardized fractions of X. granatum (CDR-134 F194) and X. molluccensis (CDR-267 F018) by measuring the status of blood glucose, serum insulin, lipid levels, hepatic and renal function markers of high fructose high fed streptozotocin treated rats and high sucrose high fat diet fed-low dosed Streptozotocin treated diabetic rats.Methods: Male rats of Sprague Dawley strain of body weight around 150 g when kept on high fructose high fat diet and high sucrose high fat diet for two weeks, respectively, showed abnormal glucose tolerance, dyslipidemia and obesity and at this stage when streptozotocin was given intraperitoneally at 45.0 mg/kg body weight caused persistent hyperglycemia in them addition to dyslipidemia along with impairment in their hepatic and renal functions.Results: The standardized fractions of X. granatum (CDR-134 F194) and X. molluccensis (CDR-267F018) when given to these high fructose high fat fed low dosed streptozotocin treated diabetic rats or high sucrose high fat diet fed-low dosed streptozotocin treated diabetic rats for 10 consecutive days showed significant improvement in their glucose intolerance, decline in their serum triglycerides and LDL-cholesterol levels. These CDR-134 F194 and CDR-267 F018 treated rats also showed elevation in their HDL-cholesterol levels and improvement in their hepatic and renal functions as evidenced by decline in SGOT, SGPT, urea, uric acid and creatinine levels.Conclusion: The present study thus concludes that the antidiabetic efficacy of standardized fractions of X. granatum (CDR-134 F194) and X. molluccensis (CDR-267F018) have favorable effect in bringing down the severity of hyperglycemia, hyperlipidemia, decline the increased level of renal and hepatic function markers and also improving glucose tolerance activity

ANTIHYPERGLYCEMIC AND ANTIDYSLIPIDEMIC ACTIVITY IN ETHYL ACETATE FRACTION OF THE FRUITS OF XYLOCARPUS GRANATUM AND XYLOCARPUS MOLUCCENSIS

Objectives: Although various species of Xylocarpus i. e. Granatum, moluccensis are known for their medicinal properties. Yet, its anti-diabetic activity remains to be defined. So the aim of this study was to evaluate the antihyperglycemic and antidyslipidemic activity in ethyl acetate fraction of the fruits of X. granatum and X. moluccensis on validated animal models as well as in-vitro glucose uptake stimulatory effect and their cytotoxicity effect in L6 skeletal muscle cells.Methods: The ethyl acetate fraction of the fruits of X. granatum and X. moluccensis were administered to diabetic groups daily up to 10 days for prolonged study. Biochemical parameters notably glucose tolerance, insulin level, lipid profile were assessed. The ethyl acetate fraction of the fruits of X. granatum and X. moluccensis were also tested for glucose uptake effect by skeletal muscle cells in the concentration dependent manner.Results: The present study show that the ethyl acetate fraction of the fruits of X. granatum as well as X. moluccensis are effective in improving glucose tolerance, declining blood glucose as well as serum cholesterol and triglycerides levels in low dosed streptozotocin-induced diabetic rats and dyslipidemic hamsters, respectively. These fractions were also found efficient in increasing glucose uptake by L6 skeletal muscle cells but did not show any effect on cell viability of L6 skeletal muscle cells.Conclusion: Based on the results, the present study revealed that ethyl acetate fraction of the fruits of X. granatum and X. moluccensis lowered blood glucose profile by increasing the glucose uptake by L-6 and this may be the possible mechanisms for the antidiabetic and antidyslipidemic action

ROLE OF DIET AND LIFESTYLE IN THE PREVENTION OF MADHUMEHA

Ayurveda is a natural health care system that originated in India since the beginning of civilization. It is described by Acharaya Charak that to achieve Purushartha Chatushtaya, Arogya is necessary. Ayurveda strongly emphasize on preventive and promotive aspects of health rather than curative. The concepts of Dincharya, Ritucharya, Sadvritta, and Achara Rasayana along with guidelines for healthy diet and lifestyle is well established in Ayurveda, but in current scenario, hardly anyone aptly follow it. As a result, there is tremendous rise in lifestyle disorders as pandemics, Diabetes being most menacing among them. Diabetes is the fourth leading cause of global death by disease. Type 2 DM is responsible for approximately 90% of cases. In Ayurveda, Madhumeha one of the types of Vataja Prameha is compared to Diabetes Mellitus because of having similarities of disease in respect to etiopathogenesis, clinical features and prognosis. The main causes of Madhumeha are lack of exercise, improper food habits, excessive intake of food having Snigdha and Guru Guna and food which causes vitiation of Kapha Dosha. Modern therapeutics has many limitations but Ayurvedic principles of management can help the patient to control blood glucose level and have better routine life. So Ayurvedic lifestyle guidelines of adopting a healthy dietary pattern together with physical activity are valuable tools in the prevention of Madhumeha

PHARMACOLOGICAL STUDY OF AMALAKI WITH SPECIAL REFERENCE TO ITS ANTIMICROBIAL ACTION

Emblica officinalis popularly known as Amalaki and Indian Goose Berry in English belongs to family Euphorbeaceae. Amalaki is gift of nature to mankind and is known as Amritphala in Sanskrit which means “Fruit of Heavenâ€. Amalaki is widely distributed in tropical and subtropical areas and has therapeuticpotential against deleterious diseases. Earlier it becomes a notable fruitfor its rich amount of vitamin C, polyphenols such as tannins, gallicacid, ellagic acid, flavonoids like quercetin and rutin. Emblica officinalis (Amla) are widely used in the Indian system of medicineand believed to increase defense against diseases. Emblica officinalis is a versatile plant due to its various medicinal properties. Emblica officinalis seeds, leaves and fruits are commonly used for medicinal purpose. The various medicinal properties of Emblica officinalis such as Antioxidant, Antipyretic, Analgesic, Cytoprotective, Anti-ulcer, Immune modulatory, Anti Inflammatory, Antitussive and Gastro-protective have been studied. Emblica officinalis having a strong Memory enhancing property, cholesterol lowering, applicable in ophthalmic disorder, are reviewed. The effects of Emblica officinalis also take account as an Antimicrobial action and in neutralizing snake venom are also included. It is used as a single remedy and as content in many medicinal preparations. The current review is to summarize Description, Phytochemistry, Therapeutic Activity, Pharmacological Activity of Emblica officinalis, which may be helpful to establish a Standard Natural drug as an Antimicrobial.

Serum Prolidase Activity and Oxidative Stress in Diabetic Nephropathy and End Stage Renal Disease: A Correlative Study with Glucose and Creatinine

Association of oxidative stress and serum prolidase activity (SPA) has been reported in many chronic diseases. The study was aimed at evaluating the correlation of glucose and creatinine to SPA and oxidative stress in patients with diabetic nephropathy (DN) and end stage renal disease (ESRD) concerned with T2DM. 50 healthy volunteers, 50 patients with T2DM, 86 patients with DN, and 43 patients with ESRD were considered as control-1, control-2, case-1, and case-2, respectively. Blood glucose, creatinine, SPA, total oxidant status (TOS), total antioxidant status (TAS), and oxidative stress index (OSI) were measured by colorimetric tests. SPA, TOS, and OSI were significantly increased in case-1 and case-2 than control-1 and control-2, while TAS was significantly decreased (P<0.001). Blood glucose was linearly correlated to SPA, TOS, TAS, and OSI in control-2, case-1 and case-2 (P<0.001). Serum creatinine was linearly correlated with SPA, TOS, TAS and OSI in control-2 and case-1 (P<0.001). In case-2, serum creatinine was significantly correlated with SPA only (P<0.001). Thus, the study concluded that SPA and oxidative stress significantly correlated with blood glucose and creatinine. SPA, TOS, TAS, and OSI can be used as biomarkers for diagnosis of kidney damage

Incoherent Effect of Fe and Ni Substitutions in the Ferromagnetic-Insulator La0.6Bi0.4MnO3+d

A comparative study of the effect of Fe and Ni doping on the bismuth based perovskite La0.6Bi0.4MnO3.1, a projected spintronics magnetic semiconductor has been carried out. The doped systems show an expressive change in magnetic ordering temperature. However, the shifts in ferromagnetic transition (TC) of these doped phases are in opposite direction with respect to the parent phase TC of 115 K. The Ni-doped phase shows an increase in TC ~200 K, whereas the Fe-doped phase exhibits a downward shift to TC~95 K. Moreover, the Fe-doped is hard-type whereas the Ni-doped compound is soft-type ferromagnet. It is observed that the materials are semiconducting in the ferromagnetic phase with activation energies of 77 & 82 meV for Fe & Ni-doped phases respectively. In the presence of external magnetic field of 7 Tesla, they exhibit minor changes in the resistivity behaviours and the maximum isothermal magnetoresistance is around -20 % at 125 K for the Ni-phase. The results are explained on the basis of electronic phase separation and competing ferromagnetic and antiferromagnetic interactions between the various mixed valence cations.Comment: 18 pages including figure

Effect of Training Programme on Knowledge and Adoption Behaviour of Farmers on Wheat Production Technologies

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