Education for sustainable development and meat consumption among inhabitants of two Maltese districts - a qualitative study

Malta and Gozo, two small islands forming part of the Maltese archipelago, are so near yet so distinct. As the two islands possess differing geographical features, two districts were selected – the predominantly urban Northern Harbour District (NHD) in Malta and the fertile rural district of Gozo – the main aim being to determine whether there is a relation between the inhabitants’ geographical location, the extent of meat consumption and the possible links of education for sustainable development to a sustainable diet. In fact, global patterns of meat consumption differ between and within countries. In view of this, the role played by the geographical location together with other motivating factors affecting meat consumption were explored, as also the level of awareness related to the environmental impact of meat production. Awareness on how our dietary choices impact our health and the environment is vital and the key vehicle required for citizens to be informed is Education for Sustainable Development (ESD). The qualitative data was collected through four focus groups – two for each district – with the data collected being mainly analysed through thematic analysis. Based on the results emerging from the transcribed focus group texts, this study reveals that the absolute majority of participants in both districts are meat eaters although their meat consumption patterns differ. Gozitans are still more inclined to adhere to the traditional way of life, conforming to religious practices by including a variety of non-meat local produce in their menus. While taste and health are the two most determining factors for consuming meat, chicken is the preferred meat of both districts. The absolute majority are unaware of the negative environmental impact of meat production and consumption, although Gozitans are more knowledgeable about current farming systems. This study therefore reveals that geographical location does have an influential role in the dietary patterns of its inhabitants and that environmental attitudes are not a strong deciding factor. This study continues to uphold the vision that culture should be considered as one of the main pillars of ESD.peer-reviewe

A comparison of clinical paediatric murmur assessment with echocardiography

Objective: To compare the clinical acumen of paediatric cardiovascular examination between various hospital paediatrician grades. Design: Prospective data collection of clinical and echocardiography findings on paediatric echocardiography referrals. Setting and patients: All paediatric patients (birth - 14 years) referred for echocardiography, in a regional hospital catering for the island population of Malta. Echocardiography was carried out by three paediatricians with tertiary training in this technique. Main outcome measures: Pre-echocardiography clinical diagnoses were compared with echocardiography results according to grade of referring hospital doctor (ranging from houseman to consultant). Both normal and abnormal hearts at echocardiography were included. Results: Echocardiographers had the highest clinical accuracy and the highest attempts at reaching a clinical diagnosis. Accuracy and attempts at diagnosis decreased as doctor's hospital grade decreased, from consultant to houseman. Ventricular septal defect was the most easily diagnosed lesion. Atrial septal defect was often misdiagnosed as pulmonary stenosis.peer-reviewe

Cardiac arrest recognition and telephone CPR by emergency medical dispatchers

Emergency Medical Service (EMS) systems annually encounters about 275 000 out-of-hospital cardiac arrest (OHCA) patients in Europe and approximately 420,000 cases in the United States.1 Survival rates have been reported to be poor with approximately 10% survival to hospital discharge.2 The chance of surviving from an OHCA is highly associated with Emergency Medical Dispatchers’ (EMD) recognition of cardiac arrest, early bystander cardiopulmonary resuscitation (CPR), and early defibrillation.3-6 This study was a simulation based study. All emergency nurses who were eligible by training to answer 112 calls and activate the EMS were included in this study. The simulations were run by two experienced ED nurses who followed predefined scripts. The two key questions that the authors were after included ascertaining patient responsiveness and breathing status. EMDs who offered telephone assisted CPR (tCPR) were noted and observed. The mean percentage recognition of out of hospital cardiac arrest by the Maltese EMDs was 67%. 28% of EMDs who recognized cardiac arrest asked both questions regarding patient’s responsiveness and breathing whilst only 8% of EMDs who did not recognize cardiac arrest asked both questions. The mean percentage of telephone assisted CPR was 58%. Conclusion: When compared to other European countries, OHCA recognition by Maltese EMDs needs to improve. However, given that the local EMDs have no formal guidelines or algorithms for their use during 112 calls, results are encouraging to say the least especially in telephone assisted CPR. With educatiopeer-reviewe

Renal thromboembolism in tako-tsubo cardiomyopathy in spite of anticoagulation

SummaryAn elderly lady was admitted with chest pain and an electrocardiogram depicting ST segment elevation, indicative of a myocardial infarction. She was treated with intra-venous tissue plasminogen activator. On coronary angiography there was a dilated and akinetic left ventricular apex but no significant coronary artery disease. She was diagnosed with tako-tsubo cardiomyopathy. An echocardiogram performed two days later demonstrated a thrombus in the left ventricular apex. Despite immediate anticoagulation with intravenous unfractionated heparin, she sustained a renal thromboembolic phenomenon

Work hard, party harder:drug use and sexual behaviour in young British casual workers in Ibiza, Spain

Background: Every summer, young people flock to nightlife-focused holiday resorts around the world to find casual work. Despite being exposed to hedonistic environments, often for several months, little is known about their substance use, sexual activity and health service needs over this extended amount of time abroad. Methods: A short anonymous questionnaire examining alcohol and drug use, sexual behaviour and use of health services was administered to young British casual workers aged 16–35 in San Antonio, Ibiza (n = 171). Results: 97.7% of casual workers used alcohol in Ibiza, and the majority (85.3%) used drugs. Almost half (43.5%) of all participants used a drug in Ibiza that they had never used in the UK. Most casual workers arrived in Ibiza without a partner or spouse (86.5%). Of these, 86.9% had sex during their stay and 50.0% had unprotected sex; often while under the influence of alcohol. Only 14.3% of those having unprotected sex with a new partner sought a sexual health check-up in Ibiza, although 84.1% intended to do this on their return to the UK. Conclusion: Substance use and sexual risk taking is widespread among young British casual workers in Ibiza. Such international nightlife resorts represent key settings for substance-related health and social problems, and for the international spread of sexually transmitted infections. Addressing the health needs of casual workers and the environments that permit and promote their excessive behaviour requires collaboration between authorities in home and destination countries and the tourism industry

Mi-Learn : an evaluation of an m-learning management system

M-Learning is a novel concept concerned with delivering learning content over mobile devices, which today is being seen as a way to support for conventional and collaborative learning as well as for extending the scope of e-learning. This paper presents the work carried out on a research project named Mi-Learn, whose goal is that of gathering background knowledge within the field of m-learning, identification of related research problems, and creating an environment where solutions to these problems can be identified and evaluated. Pocket SCORM initiatives such as [ADL04] that are working towards a set of standards for m-learning have identified the restricted user interface and the requirement for offline learning sessions as the two major challenges in this area. The work presented in this paper forms part of the first phase of an m- learning research project and concentrates on the first of these challenges. By means of a pilot m-learning management system, an evaluation exercise was carried out in order to assess the impact of a restricted user interface on the learning experience. The evaluation carried out takes both the pedagogical and user interface aspects as the evaluation criteria. Evaluation results show that currently there seems to be a value for m-learning, but more as an extension for exiting e-learning programmes rather than a complete learning management system on its own. The results also helped in clarifying the research area and setting a direction for further research work.peer-reviewe

PMC42, a breast progenitor cancer cell line, has normal-like mRNA and microRNA transcriptomes.

INTRODUCTION: The use of cultured cell lines as model systems for normal tissue is limited by the molecular alterations accompanying the immortalisation process, including changes in the mRNA and microRNA (miRNA) repertoire. Therefore, identification of cell lines with normal-like expression profiles is of paramount importance in studies of normal gene regulation. METHODS: The mRNA and miRNA expression profiles of several breast cell lines of cancerous or normal origin were measured using printed slide arrays, Luminex bead arrays, and real-time reverse transcription-polymerase chain reaction. RESULTS: We demonstrate that the mRNA expression profiles of two breast cell lines are similar to that of normal breast tissue: HB4a, immortalised normal breast epithelium, and PMC42, a breast cancer cell line that retains progenitor pluripotency allowing in-culture differentiation to both secretory and myoepithelial fates. In contrast, only PMC42 exhibits a normal-like miRNA expression profile. We identified a group of miRNAs that are highly expressed in normal breast tissue and PMC42 but are lost in all other cancerous and normal-origin breast cell lines and observed a similar loss in immortalised lymphoblastoid cell lines compared with healthy uncultured B cells. Moreover, like tumour suppressor genes, these miRNAs are lost in a variety of tumours. We show that the mechanism leading to the loss of these miRNAs in breast cancer cell lines has genomic, transcriptional, and post-transcriptional components. CONCLUSION: We propose that, despite its neoplastic origin, PMC42 is an excellent molecular model for normal breast epithelium, providing a unique tool to study breast differentiation and the function of key miRNAs that are typically lost in cancer.RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are

Hip fractures in older persons in Malta : an epidemiological study

BACKGROUND: Hip fractures are a common cause of morbidity and mortality in older adults, and may sometimes be the result of the inability to cope with arising medical problems. The purpose of this study is dual; it is primarily a local epidemiological study of hip fractures in older persons in Malta. The secondary purpose of this study is to identify the number of patients who have had a significant hospital visit in the three months preceding the hip fracture.METHOD: Data was collected over a period of 6 months from the national general hospital of Malta; Mater Dei Hospital. Patients included were 70 years and older, and sustained a proximal hip fracture.RESULTS: The incidence of hip fractures in Malta in persons aged 70 and over is 7.29 per 1000 persons per year in females and 4.66 per 1000 persons per year in males. The 1 year mortality rate was found to be 22%. In over one quarter of the cases, there was a significant hospital visit within the 3 months prior to the hip fracture incident, one fifth of whom had a falls related visit.CONCLUSION: Hip fractures in older persons in Malta resulted in a high mortality rate and rate of admission to care homes. Incidence rate in Malta matched incidence rates in central Europe. While case prevention is still limited, we suggest an age and sex-matched control study to assess the significance of hospital visits occurring prior to hip fractures, in order to guide a direction for case prevention.peer-reviewe

The pitfalls of platform comparison: DNA copy number array technologies assessed

<p>Abstract</p> <p>Background</p> <p>The accurate and high resolution mapping of DNA copy number aberrations has become an important tool by which to gain insight into the mechanisms of tumourigenesis. There are various commercially available platforms for such studies, but there remains no general consensus as to the optimal platform. There have been several previous platform comparison studies, but they have either described older technologies, used less-complex samples, or have not addressed the issue of the inherent biases in such comparisons. Here we describe a systematic comparison of data from four leading microarray technologies (the Affymetrix Genome-wide SNP 5.0 array, Agilent High-Density CGH Human 244A array, Illumina HumanCNV370-Duo DNA Analysis BeadChip, and the Nimblegen 385 K oligonucleotide array). We compare samples derived from primary breast tumours and their corresponding matched normals, well-established cancer cell lines, and HapMap individuals. By careful consideration and avoidance of potential sources of bias, we aim to provide a fair assessment of platform performance.</p> <p>Results</p> <p>By performing a theoretical assessment of the reproducibility, noise, and sensitivity of each platform, notable differences were revealed. Nimblegen exhibited between-replicate array variances an order of magnitude greater than the other three platforms, with Agilent slightly outperforming the others, and a comparison of self-self hybridizations revealed similar patterns. An assessment of the single probe power revealed that Agilent exhibits the highest sensitivity. Additionally, we performed an in-depth visual assessment of the ability of each platform to detect aberrations of varying sizes. As expected, all platforms were able to identify large aberrations in a robust manner. However, some focal amplifications and deletions were only detected in a subset of the platforms.</p> <p>Conclusion</p> <p>Although there are substantial differences in the design, density, and number of replicate probes, the comparison indicates a generally high level of concordance between platforms, despite differences in the reproducibility, noise, and sensitivity. In general, Agilent tended to be the best aCGH platform and Affymetrix, the superior SNP-CGH platform, but for specific decisions the results described herein provide a guide for platform selection and study design, and the dataset a resource for more tailored comparisons.</p

A review of sensorless control in induction machines using HF injection, test vectors and PWM harmonics

This paper gives a review of sensorless methods developed for ac drives’ operation at very low and zero speed. The sensorless drives presented in this paper use reluctance spatial anisotropy to track the mechanical rotor position, allowing the use of vector control. To extract the position information additional test signals in form of active vector pulses or continuous high frequency signals are injected into the machine. This paper also presents a technique which does not make use of additional test signals, but only components resulting from the inverter PWM pattern. Practical results show that with all reviewed methods sensorless vector control at very low and zero speed is possible. However, disturbances (eg. coming from the inverter or magnetic saturation) affect the position signal significantly and require appropriate compensation.peer-reviewe