12 research outputs found
The metabolism of progesterone
Section I. General Introduction • •
Section II. Method for the Quantitative Determination of small amounts of
Pregnanediol in Human Urine • •
Section III. Rapid Method for the Determination of Urinary Pregnanediol suitable
for routine clinical use • •
Section IV. The Conversion of Progesterone to Urinary Pregnanediol by Human
Subjects:
Introduction •
(1) Healthy Post -Menopausal Women •
(2) Healthy Young Men •
(3) Oestrogen pretreated Post-Menopausal Women •
(4) Hysterectomised Post-Menopausal Women •
(5) Hypertensive Cases •
(6) Administration of Pregnanediol or Sodium pregnanediol glucuronidate •
(7) Continued Daily Administration of Progesterone to Post-Menopausal Women and Young Men • •
Section V. Effect of Administration of Progesterone on Excretion of Pregnanediol during Normal Pregnancy • •
Section VI. Excretion of Urinary Pregnanediol after Excision of the Corpus Luteum of Pregnancy • •
Section VII. Effect of Diethylstilboestrol Administration on Excretion of Pregnanediol in Normal and Diabetic Pregnancy • •
Section VIII. Interpretation • •
References • •
Publication
Report and commentary on the following six cases: 1. Squamous epithelioma of maxillary sinus. 2. Squamous epithelioma of mandible. 3. Recurrent sq.epith. of tongue. 4. Recurrent sq.eapillomata of tongue with syphilitic glossitis and leucoplakia. 5. Recurrent squamous epithelioma of tonsil. 6. Leucoplakia and recurrent squamous epithelioma of vulva: Pattison Prize in Clinical Surgery, 1946
The cases in the Report, by illustrating
a series of definite aetioloical factors, suggest
a line of attack not usually available in the treatment
of neoplasms, namely, prophylaxis.Adequate treatment and follow up of cases of
a Syphilitic Globsitis; early recognition and treatment
of Buccal Leukoplakia (and especially of
Leukoplakia Vulvae); the avoidance of prolonged
dental trauma and serious consideration of resultant "simple" ulceration; the recognition of
treatment of nutritional anaemia, all these may
reduce the incidence of Succal Carcinoma despite
the ever increasing number of candidates in an
ageing population